Literature DB >> 29242079

The PNPLA3 SNP rs738409:G allele is associated with increased liver disease-associated mortality but reduced overall mortality in a population-based cohort.

Peter J Meffert1, Katja D Repp1, Henry Völzke1, F Ulrich Weiss2, Georg Homuth3, Jens P Kühn4, Markus M Lerch5, Ali A Aghdassi2.   

Abstract

Entities:  

Keywords:  Fatty liver disease; Liver-related; Mortality; PNPLA3; Population-based; Study of Health in Pomerania; Variant

Mesh：

Year:  2017        PMID： 29242079     DOI： 10.1016/j.jhep.2017.11.038

Source DB:  PubMed          Journal:  J Hepatol        ISSN： 0168-8278            Impact factor:   25.083


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  6 in total

1.  The PNPLA3 rs738409 C>G variant interacts with changes in body weight over time to aggravate liver steatosis, but reduces the risk of incident type 2 diabetes.

Authors:  Ming-Feng Xia; Huan-Dong Lin; Ling-Yan Chen; Li Wu; Hui Ma; Qian Li; Qiqige Aleteng; Yu Hu; Wan-Yuan He; Jian Gao; Hua Bian; Xiao-Ying Li; Xin Gao
Journal:  Diabetologia       Date:  2019-01-23       Impact factor: 10.122

Review 2.  Genetic contributions to NAFLD: leveraging shared genetics to uncover systems biology.

Authors:  Mohammed Eslam; Jacob George
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2019-10-22       Impact factor: 46.802

Review 3.  NAFLD and Diabetes: Two Sides of the Same Coin? Rationale for Gene-Based Personalized NAFLD Treatment.

Authors:  Ming-Feng Xia; Hua Bian; Xin Gao
Journal:  Front Pharmacol       Date:  2019-08-06       Impact factor: 5.810

Review 4.  Management of late onset urea cycle disorders-a remaining challenge for the intensivist?

Authors:  S Redant; A Empain; A Mugisha; P Kamgang; R Attou; P M Honoré; D De Bels
Journal:  Ann Intensive Care       Date:  2021-01-06       Impact factor: 6.925

5.  PNPLA3 rs738409 C>G Variant Influences the Association Between Visceral Fat and Significant Fibrosis in Biopsy-proven Nonalcoholic Fatty Liver Disease.

Authors:  Gang Li; Liang-Jie Tang; Pei-Wu Zhu; Ou-Yang Huang; Rafael S Rios; Kenneth I Zheng; Sui-Dan Chen; Hong-Lei Ma; Giovanni Targher; Christopher D Byrne; Xiao-Yan Pan; Ming-Hua Zheng
Journal:  J Clin Transl Hepatol       Date:  2021-10-22

6.  Genetic variants associated with metabolic dysfunction-associated fatty liver disease in western China.

Authors:  Shenling Liao; Kang An; Zhi Liu; He He; Zhenmei An; Qiaoli Su; Shuangqing Li
Journal:  J Clin Lab Anal       Date:  2022-07-26       Impact factor: 3.124
  6 in total

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