Simon Nennstiel1, Annkathrin Machanek1, Stefan von Delius1, Bruno Neu2, Bernhard Haller3, Mohamed Abdelhafez1, Roland M Schmid1, Christoph Schlag1. 1. Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany. 2. Medizinische Klinik II, Krankenhaus Landshut-Achdorf, Academic Teaching Hospital, Technische Universität München, Landshut, Germany. 3. Institut für Medizinische Statistik und Epidemiologie, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany.
Abstract
BACKGROUND: In obscure gastrointestinal bleeding, angioectasias are common findings in video capsule endoscopy (VCE). OBJECTIVE: The objective of this study was to identify predictors and characteristics of small bowel angioectasias. METHODS: Video capsule examinations between 1 July 2001 and 31 July 2011 were retrospectively reviewed. Patients with obscure gastrointestinal bleeding were identified, and those with small bowel angioectasia were compared with patients without a definite bleeding source. Univariate and multivariable statistical analyses for possible predictors of small bowel angioectasia were performed. RESULTS: From a total of 717 video capsule examinations, 512 patients with obscure gastrointestinal bleeding were identified. Positive findings were reported in 350 patients (68.4%) and angioectasias were documented in 153 of these patients (43.7%). These angioectasias were mostly located in the proximal small intestine (n = 86, 56.6%). Patients' age >65 years (odds ratio (OR) 2.15, 95% confidence interval (CI) 1.36-3.38, p = .001) and overt bleeding type (OR 1.89, 95% CI 1.22-2.94, p = .004) were identified as significant independent predictors of small bowel angioectasia. CONCLUSION: Angioectasias are the most common finding in VCE in patients with obscure gastrointestinal bleeding. They are mostly located in the proximal small bowel and are associated with higher age and an overt bleeding type.
BACKGROUND: In obscure gastrointestinal bleeding, angioectasias are common findings in video capsule endoscopy (VCE). OBJECTIVE: The objective of this study was to identify predictors and characteristics of small bowel angioectasias. METHODS: Video capsule examinations between 1 July 2001 and 31 July 2011 were retrospectively reviewed. Patients with obscure gastrointestinal bleeding were identified, and those with small bowel angioectasia were compared with patients without a definite bleeding source. Univariate and multivariable statistical analyses for possible predictors of small bowel angioectasia were performed. RESULTS: From a total of 717 video capsule examinations, 512 patients with obscure gastrointestinal bleeding were identified. Positive findings were reported in 350 patients (68.4%) and angioectasias were documented in 153 of these patients (43.7%). These angioectasias were mostly located in the proximal small intestine (n = 86, 56.6%). Patients' age >65 years (odds ratio (OR) 2.15, 95% confidence interval (CI) 1.36-3.38, p = .001) and overt bleeding type (OR 1.89, 95% CI 1.22-2.94, p = .004) were identified as significant independent predictors of small bowel angioectasia. CONCLUSION: Angioectasias are the most common finding in VCE in patients with obscure gastrointestinal bleeding. They are mostly located in the proximal small bowel and are associated with higher age and an overt bleeding type.
Entities:
Keywords:
Angioectasia; gastrointestinal bleeding; obscure gastrointestinal bleeding; potential small bowel bleeding; video capsule endoscopy
Authors: Tiago Ribeiro; Miguel Mascarenhas Saraiva; João P S Ferreira; Hélder Cardoso; João Afonso; Patrícia Andrade; Marco Parente; Renato Natal Jorge; Guilherme Macedo Journal: Ann Gastroenterol Date: 2021-07-02
Authors: Bruno Rosa; Reuma Margalit-Yehuda; Kelly Gatt; Martina Sciberras; Carlo Girelli; Jean-Christophe Saurin; Pablo Cortegoso Valdivia; Jose Cotter; Rami Eliakim; Flavio Caprioli; Gunnar Baatrup; Martin Keuchel; Pierre Ellul; Ervin Toth; Anastasios Koulaouzidis Journal: Endosc Int Open Date: 2021-05-27