BACKGROUND: The influence of aging on video capsule endoscopy (VCE) in obscure gastrointestinal bleeding (OGIB) has never been prospectively assessed. AIMS: To demonstrate if age is a risk factor for incomplete VCE examination in a setting of ongoing hospitalization for OGIB and if it affects the yield of VCE. METHODS: Forty-eight consecutive patients referred to our unit for obscure-overt GI bleeding from March 2007 to September 2009 were prospectively evaluated. Patients were divided into two groups according to their age: ≤65 years (group A) and >65 years (group B). The VCE completion rate and clinically significant findings were studied. RESULTS: The cecum was reached in 73% of patients. There was no difference between the two groups of patients in the VCE completion rate (78% vs. 68%, P=0.4). The overall diagnostic yield was 61%. A significant difference in the diagnostic yield between group A and group B (45% vs. 75%, P=0.04) was shown. Angiodysplasia was diagnosed in 13 out of 24 (54%) patients of group B, whereas mucosal breaks, such as erosions or ulcers, accounted for over a quarter of the group A findings. CONCLUSIONS: Old age is not a risk factor for incomplete VCE examination and it is associated with increased VCE yield.
BACKGROUND: The influence of aging on video capsule endoscopy (VCE) in obscure gastrointestinal bleeding (OGIB) has never been prospectively assessed. AIMS: To demonstrate if age is a risk factor for incomplete VCE examination in a setting of ongoing hospitalization for OGIB and if it affects the yield of VCE. METHODS: Forty-eight consecutive patients referred to our unit for obscure-overt GI bleeding from March 2007 to September 2009 were prospectively evaluated. Patients were divided into two groups according to their age: ≤65 years (group A) and >65 years (group B). The VCE completion rate and clinically significant findings were studied. RESULTS: The cecum was reached in 73% of patients. There was no difference between the two groups of patients in the VCE completion rate (78% vs. 68%, P=0.4). The overall diagnostic yield was 61%. A significant difference in the diagnostic yield between group A and group B (45% vs. 75%, P=0.04) was shown. Angiodysplasia was diagnosed in 13 out of 24 (54%) patients of group B, whereas mucosal breaks, such as erosions or ulcers, accounted for over a quarter of the group A findings. CONCLUSIONS: Old age is not a risk factor for incomplete VCE examination and it is associated with increased VCE yield.
Authors: Stuart L Triester; Jonathan A Leighton; Grigoris I Leontiadis; Suryakanth R Gurudu; David E Fleischer; Amy K Hara; Russell I Heigh; Arthur D Shiff; Virender K Sharma Journal: Am J Gastroenterol Date: 2006-05 Impact factor: 10.864
Authors: Cemal Yazici; John Losurdo; Michael D Brown; Scott Oosterveen; Robert Rahimi; Ali Keshavarzian; Leila Bozorgnia; Ece Mutlu Journal: World J Gastroenterol Date: 2012-09-28 Impact factor: 5.742
Authors: Simon Nennstiel; Annkathrin Machanek; Stefan von Delius; Bruno Neu; Bernhard Haller; Mohamed Abdelhafez; Roland M Schmid; Christoph Schlag Journal: United European Gastroenterol J Date: 2017-04-07 Impact factor: 4.623
Authors: Diana E Yung; Emanuele Rondonotti; Andry Giannakou; Tomer Avni; Bruno Rosa; Ervin Toth; Alfredo J Lucendo; Reena Sidhu; Hanneke Beaumont; Pierre Ellul; Lucian Negreanu; Victoria Alejandra Jiménez-Garcia; Deidre McNamara; Uri Kopylov; Luca Elli; Konstantinos Triantafyllou; Fahmi Shibli; Maria Elena Riccioni; Mauro Bruno; Xavier Dray; John N Plevris; A Koulaouzidis; Federico Argüelles-Arias; Aymeric Becq; Federica Branchi; María Ángeles Tejero-Bustos; Jose Cotter; Rami Eliakim; Francesca Ferretti; Ian M Gralnek; Juan Manuel Herrerias-Gutierrez; Mary Hussey; Maarten Jacobs; Gabriele Wurm Johansson; Mark McAlindon; Sara Montiero; Artur Nemeth; Marco Pennazio; Deepa Rattehalli; Ana Stemate; Annalisa Tortora; Georgios Tziatzios Journal: United European Gastroenterol J Date: 2017-02-01 Impact factor: 4.623