Literature DB >> 29237357

Understanding of the significance and health implications of asplenia in a cohort of patients with haemaglobinopathy: possible benefits of a spleen registry.

Chamath Premawardena1, Donald Bowden1,2, Zane Kaplan1,2, Claire Dendle1,3, Ian John Woolley1,3.   

Abstract

OBJECTIVES: Asplenia and hyposplenism carry a significant risk of ongoing morbidity and mortality which can be reduced by education, vaccination and antibiotic use. We aimed to assess education and other methods of prevention in a cohort of patients with haemoglobinopathy in a tertiary referral centre, which also had access to a post-splenectomy registry created to reduce post-splenectomy infection risk.
METHODS: A standardized questionnaire was used on patients who attended the service for regular therapy. Patients were also asked about standard post-splenectomy preventive therapies including antibiotics and vaccinations.
RESULTS: There were 49 patients who had either had a splenectomy or knew their spleen to be non-functional. Of these, nearly half knew themselves to be on the Victorian Spleen Registry (51.0%). The median knowledge score was 12 (range 4-17) out of a possible 18. Most significantly the benefits of the registry were not seen in terms of knowledge but in delivery of recommended vaccines and the use of a medical alert card.
CONCLUSION: This study examined knowledge and attitudes about splenectomy in a cohort of haemoglobinopathy patients in an Australian tertiary referral centre. The majority had good or fair knowledge with a strong association of some elements of post-splenectomy care with being placed on a spleen registry and having received targeted education. Implementation of systematic approaches by medical staff is likely to be the main benefit of a clinical registry approach in this setting.

Entities:  

Keywords:  Post-splenectomy; asplenia; cohort; education; implementation; infection; registry; vaccination

Mesh:

Year:  2017        PMID: 29237357     DOI: 10.1080/10245332.2017.1414910

Source DB:  PubMed          Journal:  Hematology        ISSN: 1024-5332            Impact factor:   2.269


  4 in total

1.  Impact of a spleen registry on optimal post-splenectomy vaccination and care.

Authors:  Sarah Luu; Claire Dendle; Penelope Jones; Samar Ojaimi; Ian J Woolley
Journal:  Hum Vaccin Immunother       Date:  2018-08-27       Impact factor: 3.452

Review 2.  Post-splenectomy sepsis: preventative strategies, challenges, and solutions.

Authors:  Sarah Luu; Denis Spelman; Ian J Woolley
Journal:  Infect Drug Resist       Date:  2019-09-12       Impact factor: 4.003

Review 3.  Post-splenectomy Sepsis: A Review of the Literature.

Authors:  Faryal Tahir; Jawad Ahmed; Farheen Malik
Journal:  Cureus       Date:  2020-02-06

4.  The development of a quality improvement project to improve infection prevention and management in patients with asplenia or hyposplenia.

Authors:  Natalya Elizabeth O'Neill; Jillian Baker; Richard Ward; Colleen Johnson; Linda Taggart; Michelle Sholzberg
Journal:  BMJ Open Qual       Date:  2020-08
  4 in total

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