Literature DB >> 29233939

No reason to reconsider HIF-2 as an oncogene in neuroblastoma and other cancer forms.

Sofie Mohlin1, Kristoffer von Stedingk1, Alexander Pietras2, Sven Påhlman3.   

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Year:  2017        PMID： 29233939      PMCID： PMC5754808          DOI： 10.1073/pnas.1716644115

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  10 in total

1.  The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages.

Authors:  K L Talks; H Turley; K C Gatter; P H Maxwell; C W Pugh; P J Ratcliffe; A L Harris
Journal:  Am J Pathol       Date:  2000-08       Impact factor: 4.307

Review 2.  Hypoxia-inducible factors in physiology and medicine.

Authors:  Gregg L Semenza
Journal:  Cell       Date:  2012-02-03       Impact factor: 41.582

3.  Combined epigenetic and differentiation-based treatment inhibits neuroblastoma tumor growth and links HIF2α to tumor suppression.

Authors:  Isabelle Westerlund; Yao Shi; Konstantinos Toskas; Stuart M Fell; Shuijie Li; Olga Surova; Erik Södersten; Per Kogner; Ulrika Nyman; Susanne Schlisio; Johan Holmberg
Journal:  Proc Natl Acad Sci U S A       Date:  2017-07-10       Impact factor: 11.205

4.  Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma.

Authors:  Lauren Fishbein; Ignaty Leshchiner; Vonn Walter; Ludmila Danilova; A Gordon Robertson; Amy R Johnson; Tara M Lichtenberg; Bradley A Murray; Hans K Ghayee; Tobias Else; Shiyun Ling; Stuart R Jefferys; Aguirre A de Cubas; Brandon Wenz; Esther Korpershoek; Antonio L Amelio; Liza Makowski; W Kimryn Rathmell; Anne-Paule Gimenez-Roqueplo; Thomas J Giordano; Sylvia L Asa; Arthur S Tischler; Karel Pacak; Katherine L Nathanson; Matthew D Wilkerson
Journal:  Cancer Cell       Date:  2017-02-02       Impact factor: 31.743

5.  Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype.

Authors:  Linda Holmquist-Mengelbier; Erik Fredlund; Tobias Löfstedt; Rosa Noguera; Samuel Navarro; Helén Nilsson; Alexander Pietras; Johan Vallon-Christersson; Ake Borg; Katarina Gradin; Lorenz Poellinger; Sven Påhlman
Journal:  Cancer Cell       Date:  2006-11       Impact factor: 31.743

6.  Kinetics and concentration effects of TPA-induced differentiation of cultured human neuroblastoma cells.

Authors:  S Påhlman; A I Ruusala; L Abrahamsson; L Odelstad; K Nilsson
Journal:  Cell Differ       Date:  1983-03

7.  The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development.

Authors:  H Tian; R E Hammer; A M Matsumoto; D W Russell; S L McKnight
Journal:  Genes Dev       Date:  1998-11-01       Impact factor: 11.361

Review 8.  Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway.

Authors:  William G Kaelin; Peter J Ratcliffe
Journal:  Mol Cell       Date:  2008-05-23       Impact factor: 17.970

9.  High levels of HIF-2alpha highlight an immature neural crest-like neuroblastoma cell cohort located in a perivascular niche.

Authors:  A Pietras; D Gisselsson; I Ora; R Noguera; S Beckman; S Navarro; S Påhlman
Journal:  J Pathol       Date:  2008-03       Impact factor: 7.996

10.  Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.

Authors:  Gabriela Bindea; Bernhard Mlecnik; Marie Tosolini; Amos Kirilovsky; Maximilian Waldner; Anna C Obenauf; Helen Angell; Tessa Fredriksen; Lucie Lafontaine; Anne Berger; Patrick Bruneval; Wolf Herman Fridman; Christoph Becker; Franck Pagès; Michael R Speicher; Zlatko Trajanoski; Jérôme Galon
Journal:  Immunity       Date:  2013-10-17       Impact factor: 31.745
  10 in total
  2 in total

1.  Reply to Mohlin et al.: High levels of EPAS1 are closely associated with key features of low-risk neuroblastoma.

Authors:  Isabelle Westerlund; Yao Shi; Konstantinos Toskas; Stuart M Fell; Shuijie Li; Erik Södersten; Susanne Schlisio; Johan Holmberg
Journal:  Proc Natl Acad Sci U S A       Date:  2017-12-12       Impact factor: 11.205

Review 2.  Targeting the HIF2-VEGF axis in renal cell carcinoma.

Authors:  Toni K Choueiri; William G Kaelin
Journal:  Nat Med       Date:  2020-10-05       Impact factor: 53.440
  2 in total

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