Gongbo Chen1, Yuming Guo1, Michael J Abramson1, Gail Williams2, Shanshan Li3. 1. School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia. 2. School of Public Health, The University of Queensland, Brisbane, Queensland, Australia. 3. School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia; School of Public Health, The University of Queensland, Brisbane, Queensland, Australia. Electronic address: Shanshan.Li@monash.edu.
Abstract
BACKGROUND: It's unclear whether exposures to low-level air pollution have adverse effects on birth outcomes, and which trimester-specific pregnant exposure is sensitive. OBJECTIVES: To investigate the effects of maternal exposure during each trimester and the whole pregnancy to particles with aerodynamic diameter<2.5μm (PM2.5), sulfur dioxide (SO2), nitrogen dioxide (NO2), and ozone (O3) on preterm birth (PTB) and low birth weight (LBW). METHODS: Daily data on birth records, air quality, and weather conditions were collected in Brisbane, Australia during 2003-2013. Mean concentrations of air pollutants were calculated for each trimester of pregnancy. Cox proportional hazards models were used to examine the associations between air pollution and birth outcomes. Multi-pollutant models and stratified analyses by ambient temperature were performed. RESULTS: Exposures to PM2.5, SO2, NO2, and O3 during the whole pregnancy were associated with increased risk of PTB [IQR HRs (hazard ratios with an interquartile range increase in air pollutants) and 95% confidence intervals (CIs): 1.05 (1.02, 1.08), 1.12 (1.09, 1.16), 1.07 (1.01, 1.13), and 1.13 (1.10, 1.16), respectively] and LBW [IQR HRs and 95% CIs: 1.06 (1.02, 1.10), 1.12 (1.08, 1.16), 1.11 (1.03, 1.18), and 1.13 (1.09, 1.17), respectively]. Highest HRs were observed during trimester 3, and lowest in trimester 1. For each air pollutant, stronger effects on PTB and LBW were present for exposure to low and moderate temperatures than exposure to high ambient temperature. CONCLUSIONS: Exposures to low-level air pollutants are related to adverse birth outcomes. More effective policies for air quality control could contribute to improving neonatal health.
BACKGROUND: It's unclear whether exposures to low-level air pollution have adverse effects on birth outcomes, and which trimester-specific pregnant exposure is sensitive. OBJECTIVES: To investigate the effects of maternal exposure during each trimester and the whole pregnancy to particles with aerodynamic diameter<2.5μm (PM2.5), sulfur dioxide (SO2), nitrogen dioxide (NO2), and ozone (O3) on preterm birth (PTB) and low birth weight (LBW). METHODS: Daily data on birth records, air quality, and weather conditions were collected in Brisbane, Australia during 2003-2013. Mean concentrations of air pollutants were calculated for each trimester of pregnancy. Cox proportional hazards models were used to examine the associations between air pollution and birth outcomes. Multi-pollutant models and stratified analyses by ambient temperature were performed. RESULTS: Exposures to PM2.5, SO2, NO2, and O3 during the whole pregnancy were associated with increased risk of PTB [IQR HRs (hazard ratios with an interquartile range increase in air pollutants) and 95% confidence intervals (CIs): 1.05 (1.02, 1.08), 1.12 (1.09, 1.16), 1.07 (1.01, 1.13), and 1.13 (1.10, 1.16), respectively] and LBW [IQR HRs and 95% CIs: 1.06 (1.02, 1.10), 1.12 (1.08, 1.16), 1.11 (1.03, 1.18), and 1.13 (1.09, 1.17), respectively]. Highest HRs were observed during trimester 3, and lowest in trimester 1. For each air pollutant, stronger effects on PTB and LBW were present for exposure to low and moderate temperatures than exposure to high ambient temperature. CONCLUSIONS: Exposures to low-level air pollutants are related to adverse birth outcomes. More effective policies for air quality control could contribute to improving neonatal health.
Authors: William Mueller; Kraichat Tantrakarnapa; Helinor Jane Johnston; Miranda Loh; Susanne Steinle; Sotiris Vardoulakis; John W Cherrie Journal: J Expo Sci Environ Epidemiol Date: 2021-02-18 Impact factor: 5.563
Authors: Maya A Deyssenroth; Maria José Rosa; Melissa N Eliot; Karl T Kelsey; Itai Kloog; Joel D Schwartz; Gregory A Wellenius; Shouneng Peng; Ke Hao; Carmen J Marsit; Jia Chen Journal: Environ Res Date: 2021-05-18 Impact factor: 8.431
Authors: Silvia Regina Dias Medici Saldiva; Ligia Vizeu Barrozo; Clea Rodrigues Leone; Marcelo Antunes Failla; Eliana de Aquino Bonilha; Regina Tomie Ivata Bernal; Regiani Carvalho de Oliveira; Paulo Hilário Nascimento Saldiva Journal: Int J Environ Res Public Health Date: 2018-10-12 Impact factor: 3.390
Authors: Yan Zhuang; Danlu Chen; Ruiyuan Li; Ziyue Chen; Jun Cai; Bin He; Bingbo Gao; Nianliang Cheng; Yueni Huang Journal: Int J Environ Res Public Health Date: 2018-07-17 Impact factor: 3.390