| Literature DB >> 29222778 |
Laura Facci1, Massimo Barbierato1, Stephen D Skaper2.
Abstract
Glial cell activation plays an important role in the pathogenesis of various neurodegenerative disorders as well as in chronic and neuropathic pain. This chapter describes a model which allows one to assess the individual and combined contributions of astrocytes and microglia in response to a pro-inflammatory stimulus, with emphasis on ionotropic purinergic receptors.Entities:
Keywords: Astrocytes; Cell culture; Coculture; Microglia; Neuroinflammation; Rat
Mesh:
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Year: 2018 PMID: 29222778 DOI: 10.1007/978-1-4939-7571-6_10
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745