Literature DB >> 29216044

Reply to The small molecule CLP257 does not modify activity of the K+-Cl- co-transporter KCC2 but does potentiate GABAA receptor activity.

Martin Gagnon1,2, Marc J Bergeron1,3, Jimena Perez-Sanchez1,4, Isabel Plasencia-Fernández1,4, Louis-Etienne Lorenzo1, Antoine G Godin1, Annie Castonguay1, Robert P Bonin1,5, Yves De Koninck1,3,4.   

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Year:  2017        PMID： 29216044     DOI： 10.1038/nm.4449

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


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  18 in total

1.  Molecular cloning and functional characterization of KCC3, a new K-Cl cotransporter.

Authors:  J E Race; F N Makhlouf; P J Logue; F H Wilson; P B Dunham; E J Holtzman
Journal:  Am J Physiol       Date:  1999-12

2.  Functional comparison of the K+-Cl- cotransporters KCC1 and KCC4.

Authors:  A Mercado; L Song; N Vazquez; D B Mount; G Gamba
Journal:  J Biol Chem       Date:  2000-09-29       Impact factor: 5.157

3.  Visualization of synaptic inhibition with an optogenetic sensor developed by cell-free protein engineering automation.

Authors:  Joshua S Grimley; Li Li; Weina Wang; Lei Wen; Lorena S Beese; Homme W Hellinga; George J Augustine
Journal:  J Neurosci       Date:  2013-10-09       Impact factor: 6.167

4.  Development and validation of a thallium flux-based functional assay for the sodium channel NaV1.7 and its utility for lead discovery and compound profiling.

Authors:  Yu Du; Emily Days; Ian Romaine; Kris K Abney; Kristian Kaufmann; Gary Sulikowski; Shaun Stauffer; Craig W Lindsley; C David Weaver
Journal:  ACS Chem Neurosci       Date:  2015-04-30       Impact factor: 4.418

5.  Differences in the large extracellular loop between the K(+)-Cl(-) cotransporters KCC2 and KCC4.

Authors:  Anna-Maria Hartmann; Meike Wenz; Adriana Mercado; Christof Störger; David B Mount; Eckhard Friauf; Hans Gerd Nothwang
Journal:  J Biol Chem       Date:  2010-06-01       Impact factor: 5.157

6.  Efficacy of synaptic inhibition depends on multiple, dynamically interacting mechanisms implicated in chloride homeostasis.

Authors:  Nicolas Doyon; Steven A Prescott; Annie Castonguay; Antoine G Godin; Helmut Kröger; Yves De Koninck
Journal:  PLoS Comput Biol       Date:  2011-09-08       Impact factor: 4.475

7.  APP modulates KCC2 expression and function in hippocampal GABAergic inhibition.

Authors:  Ming Chen; Jinzhao Wang; Jinxiang Jiang; Xingzhi Zheng; Nicholas J Justice; Kun Wang; Xiangqian Ran; Yi Li; Qingwei Huo; Jiajia Zhang; Hongmei Li; Nannan Lu; Ying Wang; Hui Zheng; Cheng Long; Li Yang
Journal:  Elife       Date:  2017-01-05       Impact factor: 8.140

8.  Enhancing KCC2 function counteracts morphine-induced hyperalgesia.

Authors:  Francesco Ferrini; Louis-Etienne Lorenzo; Antoine G Godin; Miorie Le Quang; Yves De Koninck
Journal:  Sci Rep       Date:  2017-06-20       Impact factor: 4.379

9.  The origin of phenotypic heterogeneity in a clonal cell population in vitro.

Authors:  Daniel Stockholm; Rachid Benchaouir; Julien Picot; Philippe Rameau; Thi My Anh Neildez; Gabriel Landini; Corinne Laplace-Builhé; Andras Paldi
Journal:  PLoS One       Date:  2007-04-25       Impact factor: 3.240

10.  Chloride extrusion enhancers as novel therapeutics for neurological diseases.

Authors:  Martin Gagnon; Marc J Bergeron; Guillaume Lavertu; Annie Castonguay; Sasmita Tripathy; Robert P Bonin; Jimena Perez-Sanchez; Dominic Boudreau; Bin Wang; Lionel Dumas; Isabelle Valade; Karine Bachand; Mariève Jacob-Wagner; Christian Tardif; Irenej Kianicka; Paul Isenring; Giorgio Attardo; Jeffrey A M Coull; Yves De Koninck
Journal:  Nat Med       Date:  2013-10-06       Impact factor: 53.440
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  7 in total

1.  Targeting ischemia-induced KCC2 hypofunction rescues refractory neonatal seizures and mitigates epileptogenesis in a mouse model.

Authors:  Brennan J Sullivan; Pavel A Kipnis; Brandon M Carter; Li-Rong Shao; Shilpa D Kadam
Journal:  Sci Signal       Date:  2021-11-09       Impact factor: 8.192

Review 2.  Molecular Mechanisms of Epilepsy: The Role of the Chloride Transporter KCC2.

Authors:  Giorgio Belperio; Claudia Corso; Carlos B Duarte; Miranda Mele
Journal:  J Mol Neurosci       Date:  2022-07-12       Impact factor: 2.866

Review 3.  The role of GABAergic signalling in neurodevelopmental disorders.

Authors:  Xin Tang; Rudolf Jaenisch; Mriganka Sur
Journal:  Nat Rev Neurosci       Date:  2021-03-26       Impact factor: 34.870

4.  Enhancing KCC2 activity decreases hyperreflexia and spasticity after chronic spinal cord injury.

Authors:  Jadwiga N Bilchak; Kyle Yeakle; Guillaume Caron; Dillon Malloy; Marie-Pascale Côté
Journal:  Exp Neurol       Date:  2021-01-13       Impact factor: 5.330

5.  Discovery of Small Molecule KCC2 Potentiators Which Attenuate In Vitro Seizure-Like Activity in Cultured Neurons.

Authors:  Francis J Prael Iii; Kwangho Kim; Yu Du; Brittany D Spitznagel; Gary A Sulikowski; Eric Delpire; C David Weaver
Journal:  Front Cell Dev Biol       Date:  2022-06-24

6.  Discovery of a Small Molecule Drug Candidate for Selective NKCC1 Inhibition in Brain Disorders.

Authors:  Annalisa Savardi; Marco Borgogno; Roberto Narducci; Giuseppina La Sala; Jose Antonio Ortega; Maria Summa; Andrea Armirotti; Rosalia Bertorelli; Andrea Contestabile; Marco De Vivo; Laura Cancedda
Journal:  Chem       Date:  2020-08-06       Impact factor: 22.804

7.  The Expanding Therapeutic Potential of Neuronal KCC2.

Authors:  Bor Luen Tang
Journal:  Cells       Date:  2020-01-17       Impact factor: 6.600
  7 in total

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