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Literature DB >> 29212889

Stem Cell Differentiation is Regulated by Extracellular Matrix Mechanics.

Lucas R Smith¹, Sangkyun Cho¹, Dennis E Discher¹.

Abstract

Stem cells mechanosense the stiffness of their microenvironment, which impacts differentiation. Although tissue hydration anti-correlates with stiffness, extracellular matrix (ECM) stiffness is clearly transduced into gene expression via adhesion and cytoskeleton proteins that tune fates. Cytoskeletal reorganization of ECM can create heterogeneity and influence fates, with fibrosis being one extreme.

Entities: Disease

Mesh：

Year: 2018 PMID： 29212889 PMCID： PMC5866410 DOI： 10.1152/physiol.00026.2017

Source DB: PubMed Journal: Physiology (Bethesda) ISSN： 1548-9221

95 in total

1. Defined three-dimensional microenvironments boost induction of pluripotency.

Authors: Massimiliano Caiazzo; Yuya Okawa; Adrian Ranga; Alessandra Piersigilli; Yoji Tabata; Matthias P Lutolf
Journal: Nat Mater Date: 2016-01-11 Impact factor: 43.841

Review 2. Tissue cells feel and respond to the stiffness of their substrate.

Authors: Dennis E Discher; Paul Janmey; Yu-Li Wang
Journal: Science Date: 2005-11-18 Impact factor: 47.728

3. Rapid disorganization of mechanically interacting systems of mammary acini.

Authors: Quanming Shi; Rajarshi P Ghosh; Hanna Engelke; Chris H Rycroft; Luke Cassereau; James A Sethian; Valerie M Weaver; Jan T Liphardt
Journal: Proc Natl Acad Sci U S A Date: 2013-12-30 Impact factor: 11.205

4. Long-range force transmission in fibrous matrices enabled by tension-driven alignment of fibers.

Authors: Hailong Wang; A S Abhilash; Christopher S Chen; Rebecca G Wells; Vivek B Shenoy
Journal: Biophys J Date: 2014-12-02 Impact factor: 4.033

5. Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate.

Authors: Nathaniel Huebsch; Praveen R Arany; Angelo S Mao; Dmitry Shvartsman; Omar A Ali; Sidi A Bencherif; José Rivera-Feliciano; David J Mooney
Journal: Nat Mater Date: 2010-04-25 Impact factor: 43.841

Review 6. Concise review: maturation phases of human pluripotent stem cell-derived cardiomyocytes.

Authors: Claire Robertson; David D Tran; Steven C George
Journal: Stem Cells Date: 2013-05 Impact factor: 6.277

7. Heart-specific stiffening in early embryos parallels matrix and myosin expression to optimize beating.

Authors: Stephanie Majkut; Timon Idema; Joe Swift; Christine Krieger; Andrea Liu; Dennis E Discher
Journal: Curr Biol Date: 2013-11-21 Impact factor: 10.834

8. Matrix rigidity regulates a switch between TGF-β1-induced apoptosis and epithelial-mesenchymal transition.

Authors: Jennifer L Leight; Michele A Wozniak; Sophia Chen; Michelle L Lynch; Christopher S Chen
Journal: Mol Biol Cell Date: 2012-01-11 Impact factor: 4.138

Review 9. Integrin-mediated mechanotransduction.

Authors: Zhiqi Sun; Shengzhen S Guo; Reinhard Fässler
Journal: J Cell Biol Date: 2016-11-08 Impact factor: 10.539

10. Mechanically patterned neuromuscular junctions-in-a-dish have improved functional maturation.

Authors: Cassandra L Happe; Kevin P Tenerelli; Anastasia K Gromova; Frederic Kolb; Adam J Engler
Journal: Mol Biol Cell Date: 2017-05-11 Impact factor: 4.138

56 in total

1. [Effects of the injectable glycol-chitosan based hydrogel on the proliferation and differentiation of human dental pulp cells].

Authors: C L Cao; C C Yang; X Z Qu; B Han; X Y Wang
Journal: Beijing Da Xue Xue Bao Yi Xue Ban Date: 2020-02-18

2. Emergent membrane morphologies in relaxed and tense membranes in presence of reversible adhesive pinning interactions.

Authors: Sreeja Kutti Kandy; Ravi Radhakrishnan
Journal: Phys Biol Date: 2019-10-21 Impact factor: 2.583

3. Analysis of fibroblast migration dynamics in idiopathic pulmonary fibrosis using image-based scaffolds of the lung extracellular matrix.

Authors: Marisa Tisler; Samuel Alkmin; Hsin-Yu Chang; Jon Leet; Ksenija Bernau; Nathan Sandbo; Paul J Campagnola
Journal: Am J Physiol Lung Cell Mol Physiol Date: 2019-11-27 Impact factor: 5.464

4. Elevated BMP and Mechanical Signaling Through YAP1/RhoA Poises FOP Mesenchymal Progenitors for Osteogenesis.

Authors: Alexandra Stanley; Su-Jin Heo; Robert L Mauck; Foteini Mourkioti; Eileen M Shore
Journal: J Bone Miner Res Date: 2019-08-19 Impact factor: 6.741

Review 5. Chitosan films for regenerative medicine: fabrication methods and mechanical characterization of nanostructured chitosan films.

Authors: Alessia De Masi; Ilaria Tonazzini; Cecilia Masciullo; Roberta Mezzena; Federica Chiellini; Dario Puppi; Marco Cecchini
Journal: Biophys Rev Date: 2019-09-16

6. Hydrogels with enhanced protein conjugation efficiency reveal stiffness-induced YAP localization in stem cells depends on biochemical cues.

Authors: Soah Lee; Alice E Stanton; Xinming Tong; Fan Yang
Journal: Biomaterials Date: 2019-02-23 Impact factor: 12.479

Review 7. The matrix in cancer.

Authors: Thomas R Cox
Journal: Nat Rev Cancer Date: 2021-02-15 Impact factor: 60.716

8. Dynamic Click Hydrogels for Xeno-Free Culture of Induced Pluripotent Stem Cells.

Authors: Matthew R Arkenberg; Nathan H Dimmitt; Hunter C Johnson; Karl R Koehler; Chien-Chi Lin
Journal: Adv Biosyst Date: 2020-09-13

9. Optimizing The Cell Seeding Protocol to Human Decellularized Ovarian Scaffold: Application of Dynamic System for Bio-Engineering.

Authors: Leila Mirzaeian; Farideh Eivazkhani; Maryam Hezavehei; Ashraf Moini; Fereshteh Esfandiari; Mojtaba Rezazadeh Valojerdi; Rouhollah Fathi
Journal: Cell J Date: 2019-10-14 Impact factor: 2.479

Review 10. Lessons from the Embryo: an Unrejected Transplant and a Benign Tumor.

Authors: Alaleh Rezalotfi; Angelos Varotsos Vrynas; Maryam Dehghanian; Nima Rezaei
Journal: Stem Cell Rev Rep Date: 2020-11-23 Impact factor: 5.739