Literature DB >> 29212694

Minimising aseptic loosening in extreme bone resections: custom-made tumour endoprostheses with short medullary stems and extra-cortical plates.

J D Stevenson1, C Wigley2, H Burton2, S Ghezelayagh2, G Morris3, S Evans3, M Parry1, L Jeys4.   

Abstract

AIMS: Following the resection of an extensive amount of bone in the treatment of a tumour, the residual segment may be insufficient to accept a standard length intramedullary cemented stem. Short-stemmed endoprostheses conceivably have an increased risk of aseptic loosening. Extra-cortical plates have been added to minimise this risk by supplementing fixation. The aim of this study was to investigate the survivorship of short-stemmed endoprostheses and extra-cortical plates. PATIENTS AND METHODS: The study involved 37 patients who underwent limb salvage surgery for a primary neoplasm of bone between 1998 and 2013. Endoprosthetic replacement involved the proximal humerus in nine, the proximal femur in nine, the distal femur in 13 and the proximal tibia in six patients. There were 12 primary (32%) and 25 revision procedures (68%). Implant survivorship was compared with matched controls. The amount of bone that was resected was > 70% of its length and statistically greater than the standard control group at each anatomical site.
RESULTS: The mean follow-up was seven years (one to 17). The mean length of the stem was 33 mm (20 to 60) in the humerus and 79 mm (34 to 100) in the lower limb. Kaplan-Meier analysis of survival of the implant according to anatomical site confirmed that there was no statistically significant difference between the short-stemmed endoprostheses and the standard stemmed controls at the proximal humeral (p = 0.84), proximal femoral (p = 0.57), distal femoral (p = 0.21) and proximal tibial (p = 0.61) sites. In the short-stemmed group, no implants with extra-cortical plate osseointegration suffered loosening at a mean of 8.5 years (range 2 to 16 years). Three of ten (30%) without osseointegration suffered aseptic loosening at a mean of 7.7 years (range 2 to 11.5 years).
CONCLUSION: When extensive resections of bone are required in the surgical management of tumours, and in revision cases, the addition of extra-cortical plates to short medullary stems has shown non-inferiority to standard length medullary stems and minimises aseptic failure. Cite this article: Bone Joint J 2017;99-B:1689-95. ©2017 The British Editorial Society of Bone & Joint Surgery.

Entities:  

Keywords:  Endoprosthesis; Extra-cortical plates; Limb salvage; Oncology; Short stem

Mesh:

Year:  2017        PMID: 29212694     DOI: 10.1302/0301-620X.99B12.BJJ-2017-0213.R1

Source DB:  PubMed          Journal:  Bone Joint J        ISSN: 2049-4394            Impact factor:   5.082


  12 in total

1.  Case Report: 3D-Printed Prosthesis for Limb Salvage and Joint Preservation After Tibial Sarcoma Resection.

Authors:  Zehao Guo; Ran Zhang; Yukang Que; Bo Hu; Shenglin Xu; Yong Hu
Journal:  Front Surg       Date:  2022-05-27

2.  Interlocking reconstruction-mode stem-sideplates preserve at-risk hips with short residual proximal femora.

Authors:  Alexander B Christ; Tomohiro Fujiwara; Mohamed A Yakoub; John H Healey
Journal:  Bone Joint J       Date:  2021-02       Impact factor: 5.082

3.  What Is the Survival of the Telescope Allograft Technique to Augment a Short Proximal Femur Segment in Children After Resection and Distal Femur Endoprosthesis Reconstruction for a Bone Sarcoma?

Authors:  Suraj Hindiskere; Eric Staals; Davide Maria Donati; Marco Manfrini
Journal:  Clin Orthop Relat Res       Date:  2021-08-01       Impact factor: 4.755

Review 4.  Advances in tumour endoprostheses: a systematic review.

Authors:  Maria A Smolle; Dimosthenis Andreou; Per-Ulf Tunn; Andreas Leithner
Journal:  EFORT Open Rev       Date:  2019-07-02

5.  Is double-strut fibula ankle arthrodesis a reliable reconstruction for bone defect after distal tibia tumor resection?-a finite element study based on promising clinical outcomes.

Authors:  Zhiqing Zhao; Taiqiang Yan; Wei Guo; Rongli Yang; Xiaodong Tang
Journal:  J Orthop Surg Res       Date:  2021-03-29       Impact factor: 2.359

6.  Hip-Preserved Reconstruction Using a Customized Cementless Intercalary Endoprosthesis With an Intra-Neck Curved Stem in Patients With an Ultrashort Proximal Femur: Midterm Follow-Up Outcomes.

Authors:  Qi You; Minxun Lu; Li Min; Yuqi Zhang; Jie Wang; Yitian Wang; Chuanxi Zheng; Yong Zhou; Chongqi Tu
Journal:  Front Bioeng Biotechnol       Date:  2022-02-28

7.  Radiographic Assessment of Aseptic Loosening of Tumor-Type Knee Prosthesis in Distal Femur.

Authors:  Zi-Ming Li; Xiu-Chun Yu; Kai Zheng
Journal:  Orthop Surg       Date:  2022-05-07       Impact factor: 2.279

8.  Distal femoral replacement - Cemented or cementless? Current concepts and review of the literature.

Authors:  Alexander B Christ; Francis J Hornicek; Nicola Fabbri
Journal:  J Clin Orthop Trauma       Date:  2021-05-08

9.  Is three-dimensional-printed custom-made ultra-short stem with a porous structure an acceptable reconstructive alternative in peri-knee metaphysis for the tumorous bone defect?

Authors:  Jie Wang; Jingjing An; Li Min; Chongqi Tu; Minxun Lu; Yuqi Zhang; Jingqi Lin; Yi Luo; Yong Zhou
Journal:  World J Surg Oncol       Date:  2021-08-08       Impact factor: 2.754

Review 10.  Implant Survival, Clinical Outcome and Complications of Megaprosthetic Reconstructions Following Sarcoma Resection.

Authors:  Christoph Theil; Jan Schwarze; Georg Gosheger; Burkhard Moellenbeck; Kristian Nikolaus Schneider; Niklas Deventer; Sebastian Klingebiel; George Grammatopoulos; Friedrich Boettner; Tom Schmidt-Braekling
Journal:  Cancers (Basel)       Date:  2022-01-11       Impact factor: 6.639

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