Vicki B Benard1, Meg Watson1, Mona Saraiya1, Rhea Harewood2, Julie S Townsend1, Antoinette M Stroup3,4, Hannah K Weir1, Claudia Allemani2. 1. Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia. 2. Cancer Survival Group, Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom. 3. Department of Epidemiology, Rutgers School of Public Health, Piscataway, New Jersey. 4. Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey.
Abstract
BACKGROUND: Overall, cervical cancer survival in the United States has been reported to be among the highest in the world, despite slight decreases over the last decade. Objective of the current study was to describe cervical cancer survival trends among US women and examine differences by race and stage. METHODS: This study used data from the CONCORD-2 study to compare survival among women (aged 15-99 years) diagnosed in 37 states covering 80% of the US population. Survival was adjusted for background mortality (net survival) with state- and race-specific life tables and was age-standardized with the International Cancer Survival Standard weights. Five-year survival was compared by race (all races, blacks, and whites). Two time periods, 2001-2003 and 2004-2009, were considered because of changes in how the staging variable was collected. RESULTS: From 2001 to 2009, 90,620 women were diagnosed with invasive cervical cancer. The proportion of cancers diagnosed at a regional or distant stage increased over time in most states. Overall, the 5-year survival was 63.5% in 2001-2003 and 62.8% in 2004-2009. The survival was lower for black women versus white women in both calendar periods and in most states; black women had a higher proportion of distant-stage cancers. CONCLUSIONS: The stability of the overall survival over time and the persistent differences in survival between white and black women in all US states suggest that there is a need for targeted interventions and improved access to screening, timely treatment, and follow-up care, especially among black women. Cancer 2017;123:5119-37. Published 2017. This article is a U.S. Government work and is in the public domain in the USA. Published 2017. This article is a U.S. Government work and is in the public domain in the USA.
BACKGROUND: Overall, cervical cancer survival in the United States has been reported to be among the highest in the world, despite slight decreases over the last decade. Objective of the current study was to describe cervical cancer survival trends among US women and examine differences by race and stage. METHODS: This study used data from the CONCORD-2 study to compare survival among women (aged 15-99 years) diagnosed in 37 states covering 80% of the US population. Survival was adjusted for background mortality (net survival) with state- and race-specific life tables and was age-standardized with the International Cancer Survival Standard weights. Five-year survival was compared by race (all races, blacks, and whites). Two time periods, 2001-2003 and 2004-2009, were considered because of changes in how the staging variable was collected. RESULTS: From 2001 to 2009, 90,620 women were diagnosed with invasive cervical cancer. The proportion of cancers diagnosed at a regional or distant stage increased over time in most states. Overall, the 5-year survival was 63.5% in 2001-2003 and 62.8% in 2004-2009. The survival was lower for black women versus white women in both calendar periods and in most states; black women had a higher proportion of distant-stage cancers. CONCLUSIONS: The stability of the overall survival over time and the persistent differences in survival between white and black women in all US states suggest that there is a need for targeted interventions and improved access to screening, timely treatment, and follow-up care, especially among black women. Cancer 2017;123:5119-37. Published 2017. This article is a U.S. Government work and is in the public domain in the USA. Published 2017. This article is a U.S. Government work and is in the public domain in the USA.
Entities:
Keywords:
cervical neoplasms; population-based survival; prevention and control; trends
Authors: Wendy A Leyden; M Michele Manos; Ann M Geiger; Sheila Weinmann; Judy Mouchawar; Kimberly Bischoff; Marianne Ulcickas Yood; Joyce Gilbert; Stephen H Taplin Journal: J Natl Cancer Inst Date: 2005-05-04 Impact factor: 13.506
Authors: Vicki B Benard; Christie R Eheman; Herschel W Lawson; Donald K Blackman; Christa Anderson; William Helsel; Sandra F Thames; Nancy C Lee Journal: Obstet Gynecol Date: 2004-03 Impact factor: 7.661
Authors: Donatus U Ekwueme; Vladislav J Uzunangelov; Thomas J Hoerger; Jacqueline W Miller; Mona Saraiya; Vicki B Benard; Ingrid J Hall; Janet Royalty; Chunyu Li; Evan R Myers Journal: Am J Prev Med Date: 2014-07-08 Impact factor: 5.043
Authors: Lauri E Markowitz; Eileen F Dunne; Mona Saraiya; Harrell W Chesson; C Robinette Curtis; Julianne Gee; Joseph A Bocchini; Elizabeth R Unger Journal: MMWR Recomm Rep Date: 2014-08-29
Authors: Vicki B Benard; Cheryll C Thomas; Jessica King; Greta M Massetti; V Paul Doria-Rose; Mona Saraiya Journal: MMWR Morb Mortal Wkly Rep Date: 2014-11-07 Impact factor: 17.586
Authors: Claudia Allemani; Rhea Harewood; Christopher J Johnson; Helena Carreira; Devon Spika; Audrey Bonaventure; Kevin Ward; Hannah K Weir; Michel P Coleman Journal: Cancer Date: 2017-12-15 Impact factor: 6.860
Authors: Thomas B Richards; S Jane Henley; Mary C Puckett; Hannah K Weir; Bin Huang; Thomas C Tucker; Claudia Allemani Journal: Cancer Date: 2017-12-15 Impact factor: 6.860
Authors: M Shayne Gallaway; S Jane Henley; C Brooke Steele; Behnoosh Momin; Cheryll C Thomas; Ahmed Jamal; Katrina F Trivers; Simple D Singh; Sherri L Stewart Journal: MMWR Surveill Summ Date: 2018-11-02
Authors: Tia N Borger; Gabriella E Puleo; Jessica N Rivera Rivera; Devin Montgomery; William R Bowling; Jessica L Burris Journal: Psychol Addict Behav Date: 2021-03-25
Authors: Vicki B Benard; J Elizabeth Jackson; April Greek; Virginia Senkomago; Warner K Huh; Cheryll C Thomas; Lisa C Richardson Journal: Cancer Med Date: 2021-05-21 Impact factor: 4.452