Literature DB >> 29203983

Role of Hepatic Resection for HCC in the era of Transplantation; an Experience of Two Tertiary Egyptian Centers.

Ahhmed Senbel1, Youssef Elmahdy2, Sameh Roshdy1, Ashraf Khater1,3, Fayez Shehatoo1, Omar Farouk1, Adel Fathi1, Emad Hamed1, Sherif Kotb1, Adel Denwer1.   

Abstract

The surgical treatments of hepatocellular carcinoma (HCC) in a cirrhotic liver include both hepatic resection and liver transplant. While the liver transplant is considered as a golden therapy, it has some obstacles including shortage of organs especially living donors, economic circumstances, and the progression of a tumor while waiting for the transplant so the second choice which is resection should have a role. In this study, 84 patients with HCC (who were legible for transplant according to Milan and extended selection criteria) were enrolled for hepatic resection. The outcome including complication and the oncologic outcome was evaluated. We followed our patients for 15 months as a median follow-up (range from 3 to 50 months); we noticed 10 tumor relapse (11.7%) and seven lost (8.3%). We also noticed no recurrence. Patients' overall survival showed a median of 15 and 50 months, respectively. We can conclude that there is reasonability for HR as an effective optional treatment for patients with HCC who are legible for transplant particularly for patients with a Child-A scoring.

Entities:  

Keywords:  Donors; Hepatocellular carcinoma; Resection; Transplantation

Year:  2017        PMID: 29203983      PMCID: PMC5705513          DOI: 10.1007/s13193-017-0679-5

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  14 in total

1.  How I manage my patients with hepatocellular carcinoma.

Authors:  Massimo Colombo; Angelo Sangiovanni
Journal:  Liver Int       Date:  2011-01       Impact factor: 5.828

Review 2.  Hepatocellular carcinoma: interventional bridging to liver transplantation.

Authors:  Andreas Lubienski
Journal:  Transplantation       Date:  2005-09-27       Impact factor: 4.939

3.  Outcomes and recurrence of initially resectable hepatocellular carcinoma meeting milan criteria: Rationale for partial hepatectomy as first strategy.

Authors:  Shinji Tanaka; Norio Noguchi; Takanori Ochiai; Atsushi Kudo; Noriaki Nakamura; Koji Ito; Toru Kawamura; Kenichi Teramoto; Shigeki Arii
Journal:  J Am Coll Surg       Date:  2006-11-28       Impact factor: 6.113

4.  Improved results of liver resection for hepatocellular carcinoma on cirrhosis give the procedure added value.

Authors:  G L Grazi; G Ercolani; F Pierangeli; M Del Gaudio; M Cescon; A Cavallari; A Mazziotti
Journal:  Ann Surg       Date:  2001-07       Impact factor: 12.969

5.  Treatment of centrally located hepatocellular carcinoma with central hepatectomy.

Authors:  Rey-Heng Hu; Po-Huang Lee; Yue-Cune Chang; Ming-Chih Ho; Sen-Chang Yu
Journal:  Surgery       Date:  2003-03       Impact factor: 3.982

6.  Resection and liver transplantation for HCC.

Authors:  Jacques Belghiti
Journal:  J Gastroenterol       Date:  2009-01-16       Impact factor: 7.527

7.  Liver transplantation for hepatocellular carcinoma: analysis of survival according to the intention-to-treat principle and dropout from the waiting list.

Authors:  Francis Y Yao; Nathan M Bass; Bev Nikolai; Timothy J Davern; Robert Kerlan; Victor Wu; Nancy L Ascher; John P Roberts
Journal:  Liver Transpl       Date:  2002-10       Impact factor: 5.799

Review 8.  Liver resection for hepatocellular carcinoma.

Authors:  Richard Bryant; Alexis Laurent; Claude Tayar; Jeanne Tran van Nhieu; Alain Luciani; Daniel Cherqui
Journal:  Surg Oncol Clin N Am       Date:  2008-07       Impact factor: 3.495

Review 9.  Novel advancements in the management of hepatocellular carcinoma in 2008.

Authors:  Josep M Llovet; Jordi Bruix
Journal:  J Hepatol       Date:  2008-02-12       Impact factor: 25.083

10.  Liver resection for transplantable hepatocellular carcinoma: long-term survival and role of secondary liver transplantation.

Authors:  Daniel Cherqui; Alexis Laurent; Nicolas Mocellin; Claude Tayar; Alain Luciani; Jeanne Tran Van Nhieu; Thomas Decaens; Monika Hurtova; Riccardo Memeo; Ariane Mallat; Christophe Duvoux
Journal:  Ann Surg       Date:  2009-11       Impact factor: 12.969

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  1 in total

Review 1.  Unique situation of hepatocellular carcinoma in Egypt: A review of epidemiology and control measures.

Authors:  Reem Ezzat; Mohamed Eltabbakh; Mohamed El Kassas
Journal:  World J Gastrointest Oncol       Date:  2021-12-15
  1 in total

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