| Literature DB >> 29203506 |
Clarabelle T Pham1, Catherine L Gibb2,3, Robert A Fitridge3, Jonathan D Karnon1.
Abstract
OBJECTIVE: Clinics have been established to provide preoperative medical consultations, and enable the anaesthetist and surgeon to deliver the best surgical outcome for patients. However, there is uncertainty regarding the effect of such clinics on surgical, in-hospital and long-term outcomes. A systematic review of the literature was conducted to determine the effectiveness of preoperative medical consultations by internal medicine physicians for patients listed for elective surgery.Entities:
Keywords: elective surgery; internal medicine physicians; preoperative medical consult; systematic review
Mesh:
Year: 2017 PMID: 29203506 PMCID: PMC5736040 DOI: 10.1136/bmjopen-2017-018632
Source DB: PubMed Journal: BMJ Open ISSN: 2044-6055 Impact factor: 2.692
Figure 1Summary of search results and study selection.
Assessment of risk of bias in included studies
| Source of bias | Macpherson and Lofgren | Auerbach | Katz | Vazirani |
| Selection bias | ||||
| Randomisation (RCT) | Permuted blocks of size 2 and 4, stratified by quartiles of anticipated LoS | – | – | – |
| Allocation concealment (RCT) | Not reported | – | – | – |
| Control for confounders (NRS) | – | Patients sampled at random; propensity score weighting | Consecutive patients | Regression methods |
| External validity (RCT and NRS) | Uncertain as study setting was more restrictive than a non-experimental setting | Potential unobserved confounding | Potential unobserved confounding | Potential unobserved confounding |
| Performance bias | ||||
| Blinding of participants and/or investigators (RCT) | No | – | – | – |
| Measurement of exposure (NRS) | – | No blinding but 5% of medical record abstractions were reviewed for data validity | No blinding | No blinding |
| Detection bias | ||||
| Blinded outcome assessment (RCT and NRS) | No blinding but 100% interobserver and intraobserver agreement* | Not reported | Not reported | Not reported |
| Attrition bias | ||||
| Completeness of follow-up (RCT and NRS) | Yes | Yes | 35 (8.3%) patients with missing medical records | Yes |
Ellipses indicate not applicable.
*A researcher re-abstracted length of stay data on 10 randomly selected records, and a physician not associated with the study abstracted length of stay from the same 10 records.
LoS, length of stay; NRS, non-randomised studies; RCT, randomised controlled trials.
Figure 2The timing of the preoperative medical consultation in each included study. *Macpherson and Lofgren7 compared preadmission medical consultations (outpatient clinic) to postadmission preoperative medical consultations (inpatient) and Auerbach et al 8 compared a medical consultation on the day before, day of or day after surgery with a medical or other specialty consultation on days other than the intervention (ie, two or more days before surgery).
Characteristics of included studies
| Study and setting | Study type | Population | Intervention | Comparator | n (patients) |
| Macpherson and Lofgren | Level II, randomised controlled trial | >50 years of age, referred from a surgeon, lived within 100 miles of study hospital | Medical preoperative evaluation clinic (outpatient) | Internal medicine evaluation, if necessary (inpatient) | 176 (intervention) |
| Auerbach | Level III 2, prospective observational cohort study with concurrent controls | >18 years of age, underwent one of the following surgeries (emergency or elective): colon surgery, cardiac bypass or valve procedures, hip or knee arthroplasty, hysterectomy, vascular surgery | Medical consultation on day before, day of or first day after surgery | Medical consultation on days other than intervention or from non-internal medicine services | 117 (intervention) |
| Katz | Level III 2, retrospective observational cohort study with concurrent controls | >50 years of age, underwent elective non-cardiac surgery | Medical consultation (as noted in patients’ medical records) | No medical consultation noted in patients’ medical records | 138* (intervention) |
| Vazirani | Level III 3, pre-post retrospective comparative study | All patients in the Veterans Health Administration database covering the following surgical specialties: ophthalmology, orthopaedics, urology, general surgery | Hospitalist-run preoperative clinic (outpatient) | Preoperative anaesthetic clinic (outpatient) | 2565 (intervention) |
*146 consultations.
Summary of effectiveness of physician-led preoperative assessment by outcome
| Outcome and study | Intervention | Comparator | Difference* |
| Macpherson and Lofgren | |||
| All patients | |||
| Preadmission for surgery | 1.6 | 2.9 | −1.3 (−0.8 to −1.8) |
| Admission for surgery | 3.6 | 3.0 | 0.6 (−0.6 to 1.8) |
| Total | 5.5 | 6.0 | −0.5 (−2.0 to 1.1) |
| Patients who had surgery | |||
| Preadmission for surgery | 1.9 | 3.0 | −1.1 (-0.5 to −1.6) |
| Admission for surgery | 4.8 | 3.9 | 0.9 (−0.6 to 2.4) |
| Total | 7.1 | 7.0 | 0.1 (−1.7 to 2.0) |
| Auerbach | |||
| Before adjustment | 10 (7–18) | 6 (4–9) | 87% (63% to 115%)† |
| After adjustment | NR | NR | 13% (2% to 26%)† |
| Vazirani | |||
| Mean (SD) | 5.28 (9.24) | 9.87 (25.4) | NR |
| ASA classification | |||
| No disturbance | NR | NR | −1.31 (SE 5.90), P=0.82 |
| Mild | NR | NR | −2.52 (SE 1.39), P=0.07 |
| Severe | NR | NR | −4.22 (SE 0.96), P<0.01 |
| Life-threatening | NR | NR | −19.70 (SE 3.81), P<0.01 |
| Auerbach | |||
| Before adjustment | 1 55 020 (101 473–292 951) | 74 237 (53 824–126 927) | 116% (88% to 148%)† |
| After adjustment | NR | NR | 24% (14% to 36%)† |
| Auerbach | |||
| Before adjustment | 60 (51.3) | 322 (27.6) | OR 2.76 (1.88 to 4.04) |
| After adjustment | NR | NR | OR 1.51 (0.98 to 2.32) |
| Katz | |||
| Unexpected ICU/death | 2 (1.4) | 4 (1.6) | P=0.9046 |
| Vazirani | 4 (0.4) | 14 (1.3) | OR 0.31 (0.10 to 0.99) |
| Macpherson and Lofgren | |||
| During admission | 10 (5.7) | 22 (12.3) | −6.6% (−0.5% to −12.7%) |
| Did not undergo surgery | 43 (24.4) | 42 (23.5) | NR |
| Vazirani | |||
| Total | 368 (14.3) | 400 (15.0) | NR |
| Medically avoidable‡ | 18 (4.9) | 34 (8.5) | P=0.065 |
| Macpherson and Lofgren | |||
| MOS SF-22 (higher score indicates better health) | |||
| Health perceptions | 38.8 | 33.1 | NS |
| Pain | 55.3 | 59.8 | NS |
| Physical function | 45.7 | 44.1 | NS |
| Social function | 62.3 | 61.2 | NS |
| Mental health | 63.0 | 58.0 | NS |
| Questionnaire adapted from RAND§ (%) | |||
| Satisfaction with care | 73 | 66 | NS |
| Dissatisfaction with care | 39 | 47 | NS |
| Rated care as very good or excellent | 64 | 54 | NS |
| Rated care as better than most or best | 62 | 54 | NS |
| Overall, very or extremely satisfied | 66 | 58 | NS |
*Difference reported as mean difference (95% CI of the difference) unless otherwise specified.
†Cost and length of stay data were log transformed to normalise data with percentage differences attributable to consultation calculated using the following equation: 100x(eβ−1).
‡As opposed to unavoidable, patient-related causes.
§Patient satisfaction questionnaire adapted from RAND.
ASA, American Society of Anesthesiologists; ICU, intensive care unit; MOS SF-22, Medical Outcomes Study Short Form-22; NR, not reported; NS, not significant, actual P value not reported; USD, United States Dollar.