Nathan Duong1, Hailey Davis1, Paula D Robinson2, Sapna Oberoi2, Danielle Cataudella3, S Nicole Culos-Reed4, Faith Gibson5, Miriam Götte6, Pamela Hinds7, Sanne L Nijhof8, Deborah Tomlinson1, Patrick van der Torre8, Elena Ladas9, Sandra Cabral2, L Lee Dupuis10, Lillian Sung11. 1. Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada. 2. Pediatric Oncology Group of Ontario, Toronto, ON, Canada. 3. Department of Pediatric Psychology, Children's Hospital, London Health Sciences Centre, London, ON, Canada. 4. Faculty of Kinesiology, University of Calgary, Calgary, AB, Canada. 5. Centre for Outcomes and Experiences Research in Children's Health, Illness, and Disability, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK; School of Health Sciences, University of Surrey, Guildford, UK. 6. University Hospital Essen, Center for Child and Adolescent Medicine, Department of Pediatric Hematology/Oncology, Essen, Germany. 7. Department of Nursing Science, Professional Practice, and Quality, Children's National Health System, WA, District of Columbia, USA; Department of Pediatrics, George Washington University, WA, District of Columbia, USA. 8. Division of Pediatrics, Wilhelmina Children's Hospital (part of UMC Utrecht), Utretch, Netherlands. 9. Division of Pediatric Hematology/Oncology/Stem Cell Transplant, Institute of Human Nutrition, and Mailman School of Public Health, Department of Epidemiology,Columbia University Medical Center, New York, NY, USA. 10. Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada; Department of Pharmacy, The Hospital for Sick Children, and Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada. 11. Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada; Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada. Electronic address: lillian.sung@sickkids.ca.
Abstract
PURPOSE: To determine whether non-physical activity mind and body practices reduce the severity of fatigue in patients with cancer or hematopoietic stem cell transplant (HSCT) recipients compared to control interventions. METHODS: We included randomized trials which compared non-physical activity mind and body practices compared with control interventions for the management of fatigue in cancer and HSCT patients. RESULTS: Among 55 trials (4975 patients), interventions were acupuncture or acupressure (n=12), mindfulness (n=11), relaxation techniques (n=10), massage (n=6), energy therapy (n=5), energizing yogic breathing (n=3) and others (n=8). When combined, all interventions significantly reduced fatigue severity compared to all controls (standardized mean difference -0.51, 95% confidence interval -0.73 to -0.29). More specifically, mindfulness and relaxation significantly reduced fatigue severity. CONCLUSIONS: Mindfulness and relaxation were effective at reducing fatigue severity in patients with cancer and HSCT recipients. Future studies should evaluate how to translate these findings into clinical practice across different patient groups.
PURPOSE: To determine whether non-physical activity mind and body practices reduce the severity of fatigue in patients with cancer or hematopoietic stem cell transplant (HSCT) recipients compared to control interventions. METHODS: We included randomized trials which compared non-physical activity mind and body practices compared with control interventions for the management of fatigue in cancer and HSCT patients. RESULTS: Among 55 trials (4975 patients), interventions were acupuncture or acupressure (n=12), mindfulness (n=11), relaxation techniques (n=10), massage (n=6), energy therapy (n=5), energizing yogic breathing (n=3) and others (n=8). When combined, all interventions significantly reduced fatigue severity compared to all controls (standardized mean difference -0.51, 95% confidence interval -0.73 to -0.29). More specifically, mindfulness and relaxation significantly reduced fatigue severity. CONCLUSIONS: Mindfulness and relaxation were effective at reducing fatigue severity in patients with cancer and HSCT recipients. Future studies should evaluate how to translate these findings into clinical practice across different patient groups.
Authors: Alexander Haussmann; Martina E Schmidt; Mona L Illmann; Marleen Schröter; Thomas Hielscher; Holger Cramer; Imad Maatouk; Markus Horneber; Karen Steindorf Journal: Cancers (Basel) Date: 2022-04-15 Impact factor: 6.575
Authors: Shelley A Johns; Will L Tarver; Ekin Secinti; Catherine E Mosher; Patrick V Stutz; Jennifer L Carnahan; Tasneem L Talib; Mackenzie L Shanahan; Micah T Faidley; Kelley M Kidwell; Kevin L Rand Journal: Crit Rev Oncol Hematol Date: 2021-03-04 Impact factor: 6.312
Authors: Sapna Oberoi; Jiayu Yang; Roberta L Woodgate; Saroj Niraula; Shantanu Banerji; Sara J Israels; Gary Altman; Sara Beattie; Rasheda Rabbani; Nicole Askin; Abha Gupta; Lillian Sung; Ahmed M Abou-Setta; Ryan Zarychanski Journal: JAMA Netw Open Date: 2020-08-03