Ahmet Veysel Polat1, Mesut Ozturk2, Behic Akyuz3, Cetin Celenk4, Mehmet Kefeli5, Cafer Polat6. 1. Department of Radiology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey. veyselp@hotmail.com. 2. Department of Radiology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey. dr.mesutozturk@gmail.com. 3. Department of Radiology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey. behicakyuz@gmail.com. 4. Department of Radiology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey. ccelenk@hotmail.com. 5. Department of Pathology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey. mehmetkefeli@gmail.com. 6. Department of General Surgery, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey. caferpolat@omu.edu.tr.
Abstract
AIMS: The aim of this study was to prospectively assess the feasibility of the Virtual Touch tissue imaging quantification (VTIQ) method of shear wave elastography (SWE) for the discrimination of parathyroid lesions and to compare the lesions' stiffness with that of cervical lymph nodes. MATERIALS AND METHODS: SWE using VTIQ was performed on 66 patients with 87 histopathologically proven parathyroid lesions (54 parathyroid adenomas and 33 parathyroid hyperplasia) and 29 patients with 31 inflammatory cervical lymph nodes. The mean SWVs of the lesions were compared and receiver operating characteristic (ROC) curve analysis was used to evaluate diagnostic performance. RESULTS: The mean SWV of parathyroid adenomas (2.16±0.33 m/s) differed significantly from those of parathyroid hyperplasia and lymph nodes (1.75±0.28 m/s and 1.86±0.37 m/s respectively, p<0.001). Selecting a cutoff value of 1.92 m/s for diagnosing adenoma led to 80% sensitivity and 82% specificity (area under the curve [AUC]: 0.832 [95% confidence interval (CI): 0.742-0.921], p< 0.001). CONCLUSIONS: The VTIQ method of SWE can contribute to the differentiation of parathyroid adenoma from parathyroid hyperplasia and cervical lymphnodes.
AIMS: The aim of this study was to prospectively assess the feasibility of the Virtual Touch tissue imaging quantification (VTIQ) method of shear wave elastography (SWE) for the discrimination of parathyroid lesions and to compare the lesions' stiffness with that of cervical lymph nodes. MATERIALS AND METHODS: SWE using VTIQ was performed on 66 patients with 87 histopathologically proven parathyroid lesions (54 parathyroid adenomas and 33 parathyroid hyperplasia) and 29 patients with 31 inflammatory cervical lymph nodes. The mean SWVs of the lesions were compared and receiver operating characteristic (ROC) curve analysis was used to evaluate diagnostic performance. RESULTS: The mean SWV of parathyroid adenomas (2.16±0.33 m/s) differed significantly from those of parathyroid hyperplasia and lymph nodes (1.75±0.28 m/s and 1.86±0.37 m/s respectively, p<0.001). Selecting a cutoff value of 1.92 m/s for diagnosing adenoma led to 80% sensitivity and 82% specificity (area under the curve [AUC]: 0.832 [95% confidence interval (CI): 0.742-0.921], p< 0.001). CONCLUSIONS: The VTIQ method of SWE can contribute to the differentiation of parathyroid adenoma from parathyroid hyperplasia and cervical lymphnodes.
Authors: Laura Cotoi; Daniela Amzar; Ioan Sporea; Andreea Borlea; Dan Navolan; Flore Varcus; Dana Stoian Journal: Int J Endocrinol Date: 2020-03-17 Impact factor: 3.257
Authors: Jacek Baj; Robert Sitarz; Marek Łokaj; Alicja Forma; Marcin Czeczelewski; Amr Maani; Gabriella Garruti Journal: Molecules Date: 2020-04-09 Impact factor: 4.411