| Literature DB >> 291943 |
Abstract
A mathematical model for the evolutionary change of restriction sites in mitochondrial DNA is developed. Formulas based on this model are presented for estimating the number of nucleotide substitutions between two populations or species. To express the degree of polymorphism in a population at the nucleotide level, a measure called "nucleotide diversity" is proposed.Mesh:
Substances:
Year: 1979 PMID: 291943 PMCID: PMC413122 DOI: 10.1073/pnas.76.10.5269
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205