Haimei Jia1, Meng Zhang2, Maoyu Chen3, Zhiwen Yang4, Jiansen Li5, Guo Huang6, Dawei Guan7, Xiaoli Cen8, Lijie Zhang9, Qiwen Feng10, Jianron Yi7, Haojie Zhong11, Huilai Ma12, Tie Song13. 1. Fuzhou Center for Disease Control and Prevention, Fuzhou Prefecture 350004 Fujian, China; Chinese Field Epidemiology Training Program (CFETP), Chinese Center for Disease Control and Prevention, Beijing 100050, China. Electronic address: haimei1103@126.com. 2. Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, Guangdong, China. Electronic address: 409782078@qq.com. 3. Jiangmen Center for Disease Control and Prevention, Jiangmen 529000 Guangdong, China. Electronic address: 359774390@qq.com. 4. Enping Center for Disease Control and Prevention, Jiangmen 529400, Guangdong, China. Electronic address: 51040754@qq.com. 5. Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, Guangdong, China. Electronic address: 16890389@qq.com. 6. Jiangmen Center for Disease Control and Prevention, Jiangmen 529000 Guangdong, China. Electronic address: 13902883459@163.com. 7. Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, Guangdong, China. Electronic address: 89407992@qq.com. 8. Enping Center for Disease Control and Prevention, Jiangmen 529400, Guangdong, China. Electronic address: 13632073883@163.com. 9. Chinese Field Epidemiology Training Program (CFETP), Chinese Center for Disease Control and Prevention, Beijing 100050, China. Electronic address: cfetpzlj@126.com. 10. Jiangmen Center for Disease Control and Prevention, Jiangmen 529000 Guangdong, China. Electronic address: 114599470@qq.com. 11. Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, Guangdong, China. Electronic address: 1151514908@qq.com. 12. Chinese Field Epidemiology Training Program (CFETP), Chinese Center for Disease Control and Prevention, Beijing 100050, China. Electronic address: mahl@chinacdc.cn. 13. Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, Guangdong, China. Electronic address: tsong@cdcp.org.cn.
Abstract
BACKGROUND: Zika virus (ZIKV) is a mosquito-borne virus spreading rapidly in the Americas, Africa, and Asia. No indigenous ZIKV infection had been seen in China. We monitored ZIKV infection among travelers returning to Enping county from ZIKV transmitting countries from 1 March to 10 April 2016. METHODS: We analyzed data including interviews; conducted laboratory test on blood, urine, saliva, conjunctival swab or semen specimens for evidence of ZIKV infection; evaluated household for presence of Aedes mosquitoes or larvae. RESULTS: A total of 925 individuals were screened, 507 (54.8%) were interviewed, 400 (43.2%) provided samples, of which 13 (3.3%) tested positive for ZIKV including 3 asymptomatic. Rash, conjunctivitis, sore throat, fever were the common symptoms; rash was more pronounced in adults than in children. ZIKV RNA was detected for 1-4 days in blood, but longer in urine and saliva (3-32 days and 2-10 days). Among interviewed, 57.0% had good knowledge about ZIKV, 45.8% were worried about ZIKV, 99.2% would go to hospital if they had infection. Aedes mosquitoes or larvae were detected in townships of infected returners. CONCLUSIONS: ZIKV was imported to China. Screening by symptoms alone is inadequate for detecting ZIKV infection. ZIKV surveillance, health-education, and vector control are necessary to decrease risk of ZIKV transmission.
BACKGROUND:Zika virus (ZIKV) is a mosquito-borne virus spreading rapidly in the Americas, Africa, and Asia. No indigenous ZIKV infection had been seen in China. We monitored ZIKV infection among travelers returning to Enping county from ZIKV transmitting countries from 1 March to 10 April 2016. METHODS: We analyzed data including interviews; conducted laboratory test on blood, urine, saliva, conjunctival swab or semen specimens for evidence of ZIKV infection; evaluated household for presence of Aedes mosquitoes or larvae. RESULTS: A total of 925 individuals were screened, 507 (54.8%) were interviewed, 400 (43.2%) provided samples, of which 13 (3.3%) tested positive for ZIKV including 3 asymptomatic. Rash, conjunctivitis, sore throat, fever were the common symptoms; rash was more pronounced in adults than in children. ZIKV RNA was detected for 1-4 days in blood, but longer in urine and saliva (3-32 days and 2-10 days). Among interviewed, 57.0% had good knowledge about ZIKV, 45.8% were worried about ZIKV, 99.2% would go to hospital if they had infection. Aedes mosquitoes or larvae were detected in townships of infected returners. CONCLUSIONS:ZIKV was imported to China. Screening by symptoms alone is inadequate for detecting ZIKV infection. ZIKV surveillance, health-education, and vector control are necessary to decrease risk of ZIKV transmission.
Authors: Jeanette J Rainey; Casey Siesel; Xiafang Guo; Lina Yi; Yuzhi Zhang; Shuyu Wu; Adam L Cohen; Jie Liu; Eric Houpt; Barry Fields; Zhonghua Yang; Changwen Ke Journal: PLoS One Date: 2022-06-28 Impact factor: 3.752