Literature DB >> 29174842

Oligonucleotide Therapies for the Lung: Ready to Return to the Clinic?

Manish Kumar1, Sterghios A Moschos2.   

Abstract

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Year:  2017        PMID： 29174842      PMCID： PMC5768660          DOI： 10.1016/j.ymthe.2017.11.002

Source DB:  PubMed          Journal:  Mol Ther        ISSN： 1525-0016            Impact factor:   11.454


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  20 in total

1.  Structure and nuclease resistance of 2',4'-constrained 2'-O-methoxyethyl (cMOE) and 2'-O-ethyl (cEt) modified DNAs.

Authors:  Pradeep S Pallan; Charles R Allerson; Andres Berdeja; Punit P Seth; Eric E Swayze; Thazha P Prakash; Martin Egli
Journal:  Chem Commun (Camb)       Date:  2012-05-22       Impact factor: 6.222

2.  Challenges and Future Prospects for the Delivery of Biologics: Oral Mucosal, Pulmonary, and Transdermal Routes.

Authors:  Javier O Morales; Kristin R Fathe; Ashlee Brunaugh; Silvia Ferrati; Song Li; Miguel Montenegro-Nicolini; Zeynab Mousavikhamene; Jason T McConville; Mark R Prausnitz; Hugh D C Smyth
Journal:  AAPS J       Date:  2017-02-13       Impact factor: 4.009

Review 3.  Clinical potential of oligonucleotide-based therapeutics in the respiratory system.

Authors:  Sterghios A Moschos; Louise Usher; Mark A Lindsay
Journal:  Pharmacol Ther       Date:  2016-10-19       Impact factor: 12.310

Review 4.  Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework.

Authors:  David Cook; Dearg Brown; Robert Alexander; Ruth March; Paul Morgan; Gemma Satterthwaite; Menelas N Pangalos
Journal:  Nat Rev Drug Discov       Date:  2014-05-16       Impact factor: 84.694

5.  Inhaled ENaC antisense oligonucleotide ameliorates cystic fibrosis-like lung disease in mice.

Authors:  Jeff R Crosby; Chenguang Zhao; Chong Jiang; Dong Bai; Melanie Katz; Sarah Greenlee; Hiroshi Kawabe; Michael McCaleb; Daniela Rotin; Shuling Guo; Brett P Monia
Journal:  J Cyst Fibros       Date:  2017-05-20       Impact factor: 5.482

Review 6.  Does epithelial sodium channel hyperactivity contribute to cystic fibrosis lung disease?

Authors:  Carey A Hobbs; Chong Da Tan; Robert Tarran
Journal:  J Physiol       Date:  2013-07-22       Impact factor: 5.182

7.  Resident alveolar macrophages suppress, whereas recruited monocytes promote, allergic lung inflammation in murine models of asthma.

Authors:  Zbigniew Zasłona; Sally Przybranowski; Carol Wilke; Nico van Rooijen; Seagal Teitz-Tennenbaum; John J Osterholzer; John E Wilkinson; Bethany B Moore; Marc Peters-Golden
Journal:  J Immunol       Date:  2014-09-15       Impact factor: 5.422

8.  Correction of a Cystic Fibrosis Splicing Mutation by Antisense Oligonucleotides.

Authors:  Susana Igreja; Luka A Clarke; Hugo M Botelho; Luís Marques; Margarida D Amaral
Journal:  Hum Mutat       Date:  2015-12-02       Impact factor: 4.878

9.  Challenges for inhaled drug discovery and development: Induced alveolar macrophage responses.

Authors:  Ben Forbes; Raegan O'Lone; Philippa Pribul Allen; Anthony Cahn; Chris Clarke; Mark Collinge; Lea Ann Dailey; Louise E Donnelly; Joseph Dybowski; David Hassall; Deon Hildebrand; Rhys Jones; Joanne Kilgour; Jan Klapwijk; Curtis C Maier; Tim McGovern; Kristen Nikula; Joel D Parry; Matthew D Reed; Ian Robinson; Lindsay Tomlinson; Alison Wolfreys
Journal:  Adv Drug Deliv Rev       Date:  2014-02-13       Impact factor: 15.470

10.  Nucleic Acid Immunity.

Authors:  G Hartmann
Journal:  Adv Immunol       Date:  2016-12-15       Impact factor: 3.543
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  2 in total

Review 1.  Beyond GalNAc! Drug delivery systems comprising complex oligosaccharides for targeted use of nucleic acid therapeutics.

Authors:  Joseph O'Sullivan; Jose Muñoz-Muñoz; Graeme Turnbull; Neil Sim; Stuart Penny; Sterghios Moschos
Journal:  RSC Adv       Date:  2022-07-14       Impact factor: 4.036

2.  Antisense oligonucleotide-based drug development for Cystic Fibrosis patients carrying the 3849+10 kb C-to-T splicing mutation.

Authors:  Yifat S Oren; Michal Irony-Tur Sinai; Anita Golec; Ofra Barchad-Avitzur; Venkateshwar Mutyam; Yao Li; Jeong Hong; Efrat Ozeri-Galai; Aurélie Hatton; Chen Leibson; Liran Carmel; Joel Reiter; Eric J Sorscher; Steve D Wilton; Eitan Kerem; Steven M Rowe; Isabelle Sermet-Gaudelus; Batsheva Kerem
Journal:  J Cyst Fibros       Date:  2021-07-02       Impact factor: 5.482
  2 in total

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