Kei Wagatsuma1, Kenta Miwa2, Muneyuki Sakata1, Keiichi Oda3, Haruka Ono4, Masashi Kameyama5, Jun Toyohara1, Kenji Ishii1. 1. Research Team for Neuroimaging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan. 2. School of Health Science, International University of Health and Welfare, Ohtawara, Japan. Electronic address: kenta5710@gmail.com. 3. Research Team for Neuroimaging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan; Faculty of Health Science, Hokkaido University of Science, Sapporo, Japan. 4. School of Health Science, International University of Health and Welfare, Ohtawara, Japan. 5. Department of Diagnostic Radiology, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan.
Abstract
PURPOSE: This study aimed to determine whether the SiPM-PET/CT, Discovery MI (DMI) performs better than the PMT-PET/CT system, Discovery 710 (D710). METHODS: The physical performance of both systems was evaluated using NEMA NU 2 standards. Contrast (%), uniformity and image noise (%) are criteria proposed by the Japanese Society of Nuclear Medicine (JSNM) for phantom tests and were determined in images acquired from Hoffman and uniform phantoms using the DMI and D710. Brain and whole-body [18F]FDG images were also acquired from a healthy male using the DMI and D710. RESULTS: The spatial resolution at 1.0cm off-center in the DMI and D710 was 3.91 and 4.52mm, respectively. The sensitivity of the DMI and D710 was 12.62 and 7.50cps/kBq, respectively. The observed peak noise-equivalent count rates were 185.6kcps at 22.5kBq/mL and 137.0kcps at 29.0kBq/mL, and the scatter fractions were 42.1% and 37.9% in the DMI and D710, respectively. The D710 had better contrast recovery and lower background variability. Contrast, uniformity and image noise in the DMI were 61.0%, 0.0225, and 7.85%, respectively. These outcomes were better than those derived from the D710 and satisfied the JSNM criteria. Brain images acquired by the DMI had better grey-to-white matter contrast and lower image noise at the edge of axial field of view. CONCLUSIONS: The DMI offers better sensitivity, performance under conditions of high count rates and image quality than the conventional PMT-PET/CT system, D710.
PURPOSE: This study aimed to determine whether the SiPM-PET/CT, Discovery MI (DMI) performs better than the PMT-PET/CT system, Discovery 710 (D710). METHODS: The physical performance of both systems was evaluated using NEMA NU 2 standards. Contrast (%), uniformity and image noise (%) are criteria proposed by the Japanese Society of Nuclear Medicine (JSNM) for phantom tests and were determined in images acquired from Hoffman and uniform phantoms using the DMI and D710. Brain and whole-body [18F]FDG images were also acquired from a healthy male using the DMI and D710. RESULTS: The spatial resolution at 1.0cm off-center in the DMI and D710 was 3.91 and 4.52mm, respectively. The sensitivity of the DMI and D710 was 12.62 and 7.50cps/kBq, respectively. The observed peak noise-equivalent count rates were 185.6kcps at 22.5kBq/mL and 137.0kcps at 29.0kBq/mL, and the scatter fractions were 42.1% and 37.9% in the DMI and D710, respectively. The D710 had better contrast recovery and lower background variability. Contrast, uniformity and image noise in the DMI were 61.0%, 0.0225, and 7.85%, respectively. These outcomes were better than those derived from the D710 and satisfied the JSNM criteria. Brain images acquired by the DMI had better grey-to-white matter contrast and lower image noise at the edge of axial field of view. CONCLUSIONS: The DMI offers better sensitivity, performance under conditions of high count rates and image quality than the conventional PMT-PET/CT system, D710.
Authors: Tinsu Pan; Samuel A Einstein; Srinivas Cheenu Kappadath; Kira S Grogg; Cristina Lois Gomez; Adam M Alessio; William C Hunter; Georges El Fakhri; Paul E Kinahan; Osama R Mawlawi Journal: Med Phys Date: 2019-05-31 Impact factor: 4.071
Authors: Konstantinos G Zeimpekis; Fotis A Kotasidis; Martin Huellner; Alexandra Nemirovsky; Philipp A Kaufmann; Valerie Treyer Journal: Eur J Nucl Med Mol Imaging Date: 2022-03-14 Impact factor: 10.057