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Literature DB >> 29160298

TDP2, TOP2, and SUMO: what is ZATT about?

Guido Zagnoli-Vieira¹, Keith W Caldecott¹.

Abstract

Recently, ZATT (also known as ZNF451 or Zpf451) was reported by Schellenberg et al. to aid the removal of Topoisomerase II cleavage complexes by stimulating the phosphodiesterase activity of Tyrosyl DNA Phosphodiesterase 2. Although the full implication of this discovery is unknown, it will help us understand how cells respond to topoisomerase-induced genome damage and chemotherapeutic topoisomerase 'poisons'.

Entities: Disease Gene

Mesh：

Substances：

Year: 2017 PMID： 29160298 PMCID： PMC5717409 DOI： 10.1038/cr.2017.147

Source DB: PubMed Journal: Cell Res ISSN： 1001-0602 Impact factor: 25.617

11 in total

1. PIASy mediates SUMO-2 conjugation of Topoisomerase-II on mitotic chromosomes.

Authors: Yoshiaki Azuma; Alexei Arnaoutov; Tadashi Anan; Mary Dasso
Journal: EMBO J Date: 2005-06-02 Impact factor: 11.598

2. TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function.

Authors: Fernando Gómez-Herreros; Janneke H M Schuurs-Hoeijmakers; Mark McCormack; Marie T Greally; Stuart Rulten; Rocío Romero-Granados; Timothy J Counihan; Elijah Chaila; Judith Conroy; Sean Ennis; Norman Delanty; Felipe Cortés-Ledesma; Arjan P M de Brouwer; Gianpiero L Cavalleri; Sherif F El-Khamisy; Bert B A de Vries; Keith W Caldecott
Journal: Nat Genet Date: 2014-03-23 Impact factor: 38.330

Review 3. Endogenous DNA Damage as a Source of Genomic Instability in Cancer.

Authors: Anthony Tubbs; André Nussenzweig
Journal: Cell Date: 2017-02-09 Impact factor: 41.582

4. Proteolytic degradation of topoisomerase II (Top2) enables the processing of Top2·DNA and Top2·RNA covalent complexes by tyrosyl-DNA-phosphodiesterase 2 (TDP2).

Authors: Rui Gao; Matthew J Schellenberg; Shar-Yin N Huang; Monica Abdelmalak; Christophe Marchand; Karin C Nitiss; John L Nitiss; R Scott Williams; Yves Pommier
Journal: J Biol Chem Date: 2014-05-07 Impact factor: 5.157

5. Novel TDP2-ubiquitin interactions and their importance for the repair of topoisomerase II-mediated DNA damage.

Authors: Timsi Rao; Rui Gao; Saeko Takada; Muthana Al Abo; Xiang Chen; Kylie J Walters; Yves Pommier; Hideki Aihara
Journal: Nucleic Acids Res Date: 2016-08-19 Impact factor: 16.971

6. A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly.

Authors: Nathalie Eisenhardt; Viduth K Chaugule; Stefanie Koidl; Mathias Droescher; Esen Dogan; Jan Rettich; Päivi Sutinen; Susumu Y Imanishi; Kay Hofmann; Jorma J Palvimo; Andrea Pichler
Journal: Nat Struct Mol Biol Date: 2015-11-02 Impact factor: 15.369

7. A human 5'-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage.

Authors: Felipe Cortes Ledesma; Sherif F El Khamisy; Maria C Zuma; Kay Osborn; Keith W Caldecott
Journal: Nature Date: 2009-10-01 Impact factor: 49.962

Review 8. Roles of eukaryotic topoisomerases in transcription, replication and genomic stability.

Authors: Yves Pommier; Yilun Sun; Shar-Yin N Huang; John L Nitiss
Journal: Nat Rev Mol Cell Biol Date: 2016-09-21 Impact factor: 113.915

9. Topoisomerase II beta interacts with cohesin and CTCF at topological domain borders.

Authors: Liis Uusküla-Reimand; Huayun Hou; Payman Samavarchi-Tehrani; Matteo Vietri Rudan; Minggao Liang; Alejandra Medina-Rivera; Hisham Mohammed; Dominic Schmidt; Petra Schwalie; Edwin J Young; Jüri Reimand; Suzana Hadjur; Anne-Claude Gingras; Michael D Wilson
Journal: Genome Biol Date: 2016-08-31 Impact factor: 13.583

10. TDP2 suppresses chromosomal translocations induced by DNA topoisomerase II during gene transcription.

Authors: Fernando Gómez-Herreros; Guido Zagnoli-Vieira; Ioanna Ntai; María Isabel Martínez-Macías; Rhona M Anderson; Andrés Herrero-Ruíz; Keith W Caldecott
Journal: Nat Commun Date: 2017-08-10 Impact factor: 14.919

8 in total

1. Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity.

Authors: Andres Canela; Yaakov Maman; Shar-Yin N Huang; Gordana Wutz; Wen Tang; Guido Zagnoli-Vieira; Elsa Callen; Nancy Wong; Amanda Day; Jan-Michael Peters; Keith W Caldecott; Yves Pommier; André Nussenzweig
Journal: Mol Cell Date: 2019-06-12 Impact factor: 17.970

2. The repair of topoisomerase 2 cleavage complexes in Arabidopsis.

Authors: Leonie Hacker; Annika Dorn; Janina Enderle; Holger Puchta
Journal: Plant Cell Date: 2022-01-20 Impact factor: 12.085

Review 3. Debulking of topoisomerase DNA-protein crosslinks (TOP-DPC) by the proteasome, non-proteasomal and non-proteolytic pathways.

Authors: Yilun Sun; Liton Kumar Saha; Sourav Saha; Ukhyun Jo; Yves Pommier
Journal: DNA Repair (Amst) Date: 2020-07-10