Literature DB >> 29159686

New cyclic sulfides extracted from Allium sativum: garlicnins P, J2, and Q.

Toshihiro Nohara1, Masateru Ono2, Naho Nishioka2, Fuka Masuda2, Yukio Fujiwara3, Tsuyoshi Ikeda4, Daisuke Nakano5, Junei Kinjo5.   

Abstract

Two atypical cyclic-type sulfides, garlicnin P (1) and garlicnin J2 (2), and one thiabicyclic-type sulfide, garlicnin Q (3), were isolated from the acetone extracts of garlic, Allium sativum, bulbs cultivated in the Kumamoto city area, and their structures characterized. Their production pathways are also discussed.

Entities:  

Keywords:  Allium sativum; Atypical cyclic-type sulfide; Garlicnin J2; Garlicnin P; Garlicnin Q; Thiabicyclic-type sulfide

Mesh：

Substances：

Year:  2017        PMID： 29159686     DOI： 10.1007/s11418-017-1151-0

Source DB:  PubMed          Journal:  J Nat Med        ISSN： 1340-3443            Impact factor:   2.343


  16 in total

1.  Isolation and characterization of new onionins A2 and A3 from Allium cepa, and of onionins A1, A2, and A3 from Allium fistulosum.

Authors:  Toshihiro Nohara; Yukio Fujiwara; Rino Kudo; Koki Yamaguchi; Tsuyoshi Ikeda; Kotaro Murakami; Masateru Ono; Tetsuya Kajimoto; Motohiro Takeya
Journal:  Chem Pharm Bull (Tokyo)       Date:  2014       Impact factor: 1.645

2.  Onionin A from Allium cepa inhibits macrophage activation.

Authors:  Mona El-Aasr; Yukio Fujiwara; Motohiro Takeya; Tsuyoshi Ikeda; Sachiko Tsukamoto; Masateru Ono; Daisuke Nakano; Masafumi Okawa; Junei Kinjo; Hitoshi Yoshimitsu; Toshihiro Nohara
Journal:  J Nat Prod       Date:  2010-07-23       Impact factor: 4.050

3.  Onionin A, a sulfur-containing compound isolated from onions, impairs tumor development and lung metastasis by inhibiting the protumoral and immunosuppressive functions of myeloid cells.

Authors:  Yukio Fujiwara; Hasita Horlad; Daisuke Shiraishi; Junko Tsuboki; Rino Kudo; Tsuyoshi Ikeda; Toshihiro Nohara; Motohiro Takeya; Yoshihiro Komohara
Journal:  Mol Nutr Food Res       Date:  2016-08-16       Impact factor: 5.914

4.  Acyclic sulfides, garlicnins L-1-L-4, E, and F, from Allium sativum.

Authors:  Toshihiro Nohara; Yukio Fujiwara; Tsuyoshi Ikeda; Koki Yamaguchi; Hideyuki Manabe; Kotaro Murakami; Masateru Ono; Daisuke Nakano; Junei Kinjo
Journal:  Chem Pharm Bull (Tokyo)       Date:  2014       Impact factor: 1.645

5.  Garlicnin A from the fraction regulating macrophage activation of Allium sativum.

Authors:  Mona El-Aasr; Yukio Fujiwara; Motohiro Takeya; Masateru Ono; Daisuke Nakano; Masafumi Okawa; Junei Kinjo; Tsuyoshi Ikeda; Hiroyuki Miyashita; Hitoshi Yoshimitsu; Toshihiro Nohara
Journal:  Chem Pharm Bull (Tokyo)       Date:  2011       Impact factor: 1.645

6.  Garlicnins B(1), C(1), and D, from the fraction regulating macrophage activation of Allium sativum.

Authors:  Toshihiro Nohara; Yuka Kiyota; Toyonobu Sakamoto; Hideyuki Manabe; Masateru Ono; Tsuyoshi Ikeda; Yukio Fujiwara; Daisuke Nakano; Junei Kinjo
Journal:  Chem Pharm Bull (Tokyo)       Date:  2012       Impact factor: 1.645

Review 7.  Antitumor Allium Sulfides.

Authors:  Toshihiro Nohara; Yukio Fujiwara; Mona El-Aasr; Tsuyoshi Ikeda; Masateru Ono; Daisuke Nakano; Junei Kinjo
Journal:  Chem Pharm Bull (Tokyo)       Date:  2017       Impact factor: 1.645

Review 8.  Clarifying the real bioactive constituents of garlic.

Authors:  Harunobu Amagase
Journal:  J Nutr       Date:  2006-03       Impact factor: 4.798

9.  Cyclic sulfoxides garlicnins B2, B3, B4, C2, and C3 from Allium sativum.

Authors:  Toshihiro Nohara; Yukio Fujiwara; Tsuyoshi Ikeda; Kohtaro Murakami; Masateru Ono; Daisuke Nakano; Junei Kinjo
Journal:  Chem Pharm Bull (Tokyo)       Date:  2013       Impact factor: 1.645

10.  Onionin A inhibits ovarian cancer progression by suppressing cancer cell proliferation and the protumour function of macrophages.

Authors:  Junko Tsuboki; Yukio Fujiwara; Hasita Horlad; Daisuke Shiraishi; Toshihiro Nohara; Shingo Tayama; Takeshi Motohara; Yoichi Saito; Tsuyoshi Ikeda; Kiyomi Takaishi; Hironori Tashiro; Yukihiro Yonemoto; Hidetaka Katabuchi; Motohiro Takeya; Yoshihiro Komohara
Journal:  Sci Rep       Date:  2016-07-12       Impact factor: 4.379
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  1 in total

Review 1.  Thiolane-type sulfides from garlic, onion, and Welsh onion.

Authors:  Toshihiro Nohara; Yukio Fujiwara; Mona El-Aasr; Tsuyoshi Ikeda; Masateru Ono; Daisuke Nakano; Junei Kinjo
Journal:  J Nat Med       Date:  2021-06-03       Impact factor: 2.343
  1 in total

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