Mary P Kotlarczyk1, Subashan Perera1,2, David A Nace1, Neil M Resnick1, Susan L Greenspan1,3. 1. Division of Geriatric Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania. 2. Department of Biostatistics, University of Pittsburgh, Pittsburgh, Pennsylvania. 3. Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Abstract
OBJECTIVES: To establish the prevalence of sarcopenia in a long-term care population, assess agreement among different consensus sarcopenia diagnostic criteria, and examine agreement of a self-reported questionnaire with consensus guidelines. DESIGN: Cross-sectional secondary analysis. SETTING: Long-term care communities in the greater Pittsburgh, Pennsylvania, area. PARTICIPANTS: Women aged 65 and older (mean 83.6) undergoing eligibility screening for a fracture reduction trial (N = 141). MEASUREMENTS: We measured appendicular lean muscle mass using dual-energy X-ray absorptiometry. Hand grip strength and usual gait speed were also evaluated. Sarcopenia status was determined according to European Working Group on Sarcopenia in Older People (EWGSOP) and the Foundation for the National Institutes of Health (FNIH) Sarcopenia Project criteria and the SARC-F questionnaire. RESULTS: Eleven participants were sarcopenic (7.8%) according to the EWGSOP criteria, six (4.3%) according to FNIH conservative cut-point guidelines, and 32.6% (n = 46) according to FNIH intermediate cut-points. Only 2 of 141 participants met criteria for sarcopenia according to all three guidelines. Sarcopenia was identified in 30 (21.3%) participants according to the SARC-F questionnaire. Sensitivity of the SARC-F with consensus panel definitions ranged from 18.2% to 33.3%. Specificity ranged from 78.7% to 81.1%. CONCLUSION: Current consensus criteria from the EWGSOP and FNIH Sarcopenia Project do not agree and have little overlap in older female long-term care residents. The SARC-F questionnaire is a simple tool that could be implemented in long-term care, but it has low sensitivity compared with current consensus guidelines in the identification of sarcopenic individuals.
OBJECTIVES: To establish the prevalence of sarcopenia in a long-term care population, assess agreement among different consensus sarcopenia diagnostic criteria, and examine agreement of a self-reported questionnaire with consensus guidelines. DESIGN: Cross-sectional secondary analysis. SETTING: Long-term care communities in the greater Pittsburgh, Pennsylvania, area. PARTICIPANTS: Women aged 65 and older (mean 83.6) undergoing eligibility screening for a fracture reduction trial (N = 141). MEASUREMENTS: We measured appendicular lean muscle mass using dual-energy X-ray absorptiometry. Hand grip strength and usual gait speed were also evaluated. Sarcopenia status was determined according to European Working Group on Sarcopenia in Older People (EWGSOP) and the Foundation for the National Institutes of Health (FNIH) Sarcopenia Project criteria and the SARC-F questionnaire. RESULTS: Eleven participants were sarcopenic (7.8%) according to the EWGSOP criteria, six (4.3%) according to FNIH conservative cut-point guidelines, and 32.6% (n = 46) according to FNIH intermediate cut-points. Only 2 of 141 participants met criteria for sarcopenia according to all three guidelines. Sarcopenia was identified in 30 (21.3%) participants according to the SARC-F questionnaire. Sensitivity of the SARC-F with consensus panel definitions ranged from 18.2% to 33.3%. Specificity ranged from 78.7% to 81.1%. CONCLUSION: Current consensus criteria from the EWGSOP and FNIH Sarcopenia Project do not agree and have little overlap in older female long-term care residents. The SARC-F questionnaire is a simple tool that could be implemented in long-term care, but it has low sensitivity compared with current consensus guidelines in the identification of sarcopenic individuals.
Authors: L P Fried; C M Tangen; J Walston; A B Newman; C Hirsch; J Gottdiener; T Seeman; R Tracy; W J Kop; G Burke; M A McBurnie Journal: J Gerontol A Biol Sci Med Sci Date: 2001-03 Impact factor: 6.053
Authors: Alfonso J Cruz-Jentoft; Jean Pierre Baeyens; Jürgen M Bauer; Yves Boirie; Tommy Cederholm; Francesco Landi; Finbarr C Martin; Jean-Pierre Michel; Yves Rolland; Stéphane M Schneider; Eva Topinková; Maurits Vandewoude; Mauro Zamboni Journal: Age Ageing Date: 2010-04-13 Impact factor: 10.668
Authors: Thuy-Tien Dam; Katherine W Peters; Maren Fragala; Peggy M Cawthon; Tamara B Harris; Robert McLean; Michelle Shardell; Dawn E Alley; Anne Kenny; Luigi Ferrucci; Jack Guralnik; Douglas P Kiel; Steve Kritchevsky; Maria T Vassileva; Stephanie Studenski Journal: J Gerontol A Biol Sci Med Sci Date: 2014-05 Impact factor: 6.053
Authors: Robert R McLean; Michelle D Shardell; Dawn E Alley; Peggy M Cawthon; Maren S Fragala; Tamara B Harris; Anne M Kenny; Katherine W Peters; Luigi Ferrucci; Jack M Guralnik; Stephen B Kritchevsky; Douglas P Kiel; Maria T Vassileva; Qian-Li Xue; Subashan Perera; Stephanie A Studenski; Thuy-Tien L Dam Journal: J Gerontol A Biol Sci Med Sci Date: 2014-05 Impact factor: 6.053
Authors: Dawn E Alley; Michelle D Shardell; Katherine W Peters; Robert R McLean; Thuy-Tien L Dam; Anne M Kenny; Maren S Fragala; Tamara B Harris; Douglas P Kiel; Jack M Guralnik; Luigi Ferrucci; Stephen B Kritchevsky; Stephanie A Studenski; Maria T Vassileva; Peggy M Cawthon Journal: J Gerontol A Biol Sci Med Sci Date: 2014-05 Impact factor: 6.053
Authors: Denise L Orwig; Jay Magaziner; Roger A Fielding; Hao Zhu; Ellen F Binder; Peggy M Cawthon; Shalender Bhasin; Rosaly Correa-de-Araujo; Todd Manini; Sheena Patel; Michelle Shardell; Thomas G Travison Journal: J Gerontol A Biol Sci Med Sci Date: 2020-06-18 Impact factor: 6.053
Authors: Gregory J Grosicki; Thomas G Travison; Hao Zhu; Jay Magaziner; Ellen F Binder; Marco Pahor; Rosaly Correa-de-Araujo; Peggy M Cawthon; Shalender Bhasin; Denise Orwig; Susan Greenspan; Todd Manini; Joe Massaro; Adam Santanasto; Sheena Patel; Roger A Fielding Journal: J Am Geriatr Soc Date: 2020-07-07 Impact factor: 5.562
Authors: Anna H Wu; V Wendy Setiawan; Unhee Lim; Chiu-Cheng Tseng; Kami K White; John Shepherd; Heinz Josef Lenz; Iona Cheng; Daniel O Stram; Christopher Haiman; Lynne R Wilkens; Loïc Le Marchand Journal: J Cachexia Sarcopenia Muscle Date: 2022-01-30 Impact factor: 12.910