Literature DB >> 29150846

Cancer stem cells as targets for immunotherapy.

Amy S Codd1, Takayuki Kanaseki2, Toshihiko Torigo2, Zsuzsanna Tabi1.   

Abstract

Current cancer therapies target the bulk of the tumour, while a population of highly resistant tumour cells may be able to repopulate the tumour and metastasize to new sites. Cancer cells with such stem cell-like characteristics can be identified based on their phenotypical and/or functional features which may open up ways for their targeted elimination. In this review we discuss potential off-target effects of inhibiting cancer stem-cell self-renewal pathways on immune cells, and summarize some recent immunological studies specifically targeting cancer stem cells based on their unique antigen expression.
© 2017 John Wiley & Sons Ltd.

Entities:  

Keywords:  T-cell; antigens/peptides/epitopes; immunotherapy; stem cell; tumour immunology

Mesh：

Substances：

Year:  2017        PMID： 29150846      PMCID： PMC5795182          DOI： 10.1111/imm.12866

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  135 in total

1.  TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells.

Authors:  Tanapat Palaga; Lucio Miele; Todd E Golde; Barbara A Osborne
Journal:  J Immunol       Date:  2003-09-15       Impact factor: 5.422

2.  Do Cancer Cell Lines Have Fixed or Fluctuating Stem Cell Phenotypes? - Studies with the NTera2 Cell Line.

Authors:  Zachariah P Sellers; Gabriela Schneider; Kamila Bujko; Malwina Suszynska; Daniel Pedziwiatr
Journal:  Stem Cell Rev Rep       Date:  2017-10       Impact factor: 5.739

3.  HSP DNAJB8 controls tumor-initiating ability in renal cancer stem-like cells.

Authors:  Satoshi Nishizawa; Yoshihiko Hirohashi; Toshihiko Torigoe; Akari Takahashi; Yasuaki Tamura; Takashi Mori; Takayuki Kanaseki; Kenjiro Kamiguchi; Hiroko Asanuma; Rena Morita; Alice Sokolovskaya; Junichi Matsuzaki; Ren Yamada; Reona Fujii; Harm H Kampinga; Toru Kondo; Tadashi Hasegawa; Isao Hara; Noriyuki Sato
Journal:  Cancer Res       Date:  2012-05-02       Impact factor: 12.701

Review 4.  Dendritic cell metabolism.

Authors:  Edward J Pearce; Bart Everts
Journal:  Nat Rev Immunol       Date:  2015-01       Impact factor: 53.106

5.  Cancer vaccination drives Nanog-dependent evolution of tumor cells toward an immune-resistant and stem-like phenotype.

Authors:  Kyung Hee Noh; Young-Ho Lee; Ju-Hong Jeon; Tae Heung Kang; Chih-Ping Mao; T-C Wu; Tae Woo Kim
Journal:  Cancer Res       Date:  2012-02-14       Impact factor: 12.701

6.  Characterization of HLA-A3-restricted cytotoxic T lymphocytes reactive against the widely expressed tumor antigen telomerase.

Authors:  R H Vonderheide; K S Anderson; W C Hahn; M O Butler; J L Schultze; L M Nadler
Journal:  Clin Cancer Res       Date:  2001-11       Impact factor: 12.531

7.  Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content.

Authors:  Salvatore Pece; Daniela Tosoni; Stefano Confalonieri; Giovanni Mazzarol; Manuela Vecchi; Simona Ronzoni; Loris Bernard; Giuseppe Viale; Pier Giuseppe Pelicci; Pier Paolo Di Fiore
Journal:  Cell       Date:  2010-01-08       Impact factor: 41.582

8.  Enhancement of T cell responses as a result of synergy between lower doses of radiation and T cell stimulation.

Authors:  Lisa K Spary; Saly Al-Taei; Josephine Salimu; Alexander D Cook; Ann Ager; H Angharad Watson; Aled Clayton; John Staffurth; Malcolm D Mason; Zsuzsanna Tabi
Journal:  J Immunol       Date:  2014-03-05       Impact factor: 5.422

9.  HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers.

Authors:  Marc L Mendillo; Sandro Santagata; Martina Koeva; George W Bell; Rong Hu; Rulla M Tamimi; Ernest Fraenkel; Tan A Ince; Luke Whitesell; Susan Lindquist
Journal:  Cell       Date:  2012-08-03       Impact factor: 41.582

10.  Numb-like (NumbL) downregulation increases tumorigenicity, cancer stem cell-like properties and resistance to chemotherapy.

Authors:  José M García-Heredia; Eva M Verdugo Sivianes; Antonio Lucena-Cacace; Sonia Molina-Pinelo; Amancio Carnero
Journal:  Oncotarget       Date:  2016-09-27
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  25 in total

Review 1.  Targeting signalling pathways and the immune microenvironment of cancer stem cells - a clinical update.

Authors:  Joseph A Clara; Cecilia Monge; Yingzi Yang; Naoko Takebe
Journal:  Nat Rev Clin Oncol       Date:  2019-12-02       Impact factor: 66.675

Review 2.  Drug resistance mechanisms of cancer stem-like cells and their therapeutic potential as drug targets.

Authors:  Takahiko Murayama; Noriko Gotoh
Journal:  Cancer Drug Resist       Date:  2019-09-19

3.  KIF4A facilitates cell proliferation via induction of p21-mediated cell cycle progression and promotes metastasis in colorectal cancer.

Authors:  Ping-Fu Hou; Tao Jiang; Fang Chen; Pei-Cong Shi; Hai-Qing Li; Jin Bai; Jun Song
Journal:  Cell Death Dis       Date:  2018-05-01       Impact factor: 8.469

4.  Expression levels of a gene signature in hiPSC associated with lung adenocarcinoma stem cells and its capability in eliciting specific antitumor immune-response in a humanized mice model.

Authors:  Jingbo Wang; Lijuan Shao; Liujing Wu; Wei Ma; Yuanyuan Zheng; Chaofeng Hu; Furong Li
Journal:  Thorac Cancer       Date:  2020-04-20       Impact factor: 3.500

Review 5.  Cancer stem cells and tumorigenesis.

Authors:  Pingping Zhu; Zusen Fan
Journal:  Biophys Rep       Date:  2018-08-29

6.  Immune Curbing of Cancer Stem Cells by CTLs Directed to NANOG.

Authors:  Christina Wefers; Gerty Schreibelt; Leon F A G Massuger; I Jolanda M de Vries; Ruurd Torensma
Journal:  Front Immunol       Date:  2018-06-19       Impact factor: 7.561

Review 7.  Recent Advances in Cancer Stem Cell-Targeted Immunotherapy.

Authors:  Narayanasamy Badrinath; So Young Yoo
Journal:  Cancers (Basel)       Date:  2019-03-05       Impact factor: 6.639

8.  Array expression meta-analysis of cancer stem cell genes identifies upregulation of PODXL especially in DCC low expression meningiomas.

Authors:  Hans-Juergen Schulten; Deema Hussein
Journal:  PLoS One       Date:  2019-05-13       Impact factor: 3.240

Review 9.  Concise Reviews: Cancer Stem Cell Targeted Therapies: Toward Clinical Success.

Authors:  Amar Desai; Yan Yan; Stanton L Gerson
Journal:  Stem Cells Transl Med       Date:  2018-10-17       Impact factor: 6.940

Review 10.  Recent Progress of Stem Cell Therapy in Cancer Treatment: Molecular Mechanisms and Potential Applications.

Authors:  Dinh-Toi Chu; Tiep Tien Nguyen; Nguyen Le Bao Tien; Dang-Khoa Tran; Jee-Heon Jeong; Pham Gia Anh; Vo Van Thanh; Dang Tien Truong; Thien Chu Dinh
Journal:  Cells       Date:  2020-02-28       Impact factor: 6.600
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