| Literature DB >> 29149609 |
Raquel Salvador-Gallego1, Melissa J Hoyer1, Gia K Voeltz1.
Abstract
The endoplasmic reticulum (ER) consists of the nuclear envelope and a reticulated interconnected network of tubules and sheets. ER sheets are studded with ribosomes and provide the entryway for proteins into the secretory pathway. ER tubules move dynamically on microtubules and form membrane contact sites with other organelles, where membranes are tethered, but not fused. This Snapshot reviews key biological processes that take place at ER contact sites with the Golgi, endosomes, and mitochondria.Mesh:
Substances:
Year: 2017 PMID: 29149609 DOI: 10.1016/j.cell.2017.11.005
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582