Literature DB >> 29149370

[Hematological diagnosis in the corneal consultation].

J Wasielica-Poslednik1, A Gericke2, M Munder3, N Pfeiffer2, W Lisch2.   

Abstract

This case report describes a diagnostic chain in a patient with atypical bilateral corneal opacity, which led to the diagnosis of a hematological disorder. The patient's medical history, clinical appearance and findings in confocal microscopy gave rise to the suspicion of a paraproteinemic keratopathy. The hematological laboratory diagnostics revealed a monoclonal gammopathy of the IgG kappa type. The bone marrow puncture led to the diagnosis of a lymphoplasmacytic lymphoma, which belongs to the group of B‑cell non-Hodgkin's lymphomas. This case demonstrates that paraproteinemic keratopathy can be associated with potentially life-threatening hematological diseases.

Entities:  

Keywords:  Confocal microscopy; Immunotactoid keratopathy; Lymphoplasmacytic lymphoma; Monoclonal gammopathy; Paraproteinemic keratopathy

Mesh:

Year:  2018        PMID: 29149370     DOI: 10.1007/s00347-017-0615-7

Source DB:  PubMed          Journal:  Ophthalmologe        ISSN: 0941-293X            Impact factor:   1.059


  4 in total

Review 1.  Waldenström macroglobulinemia: What a hematologist needs to know.

Authors:  Prashant Kapoor; Jonas Paludo; Nishanth Vallumsetla; Philip R Greipp
Journal:  Blood Rev       Date:  2015-03-24       Impact factor: 8.250

2.  [Paraproteinemic Keratopathy as a Clinical Sign of Monoclonal Gammopathy].

Authors:  J Wasielica-Poslednik; A Gericke; N Pfeiffer; W Lisch
Journal:  Klin Monbl Augenheilkd       Date:  2017-04-05       Impact factor: 0.700

3.  The Hematologic Definition of Monoclonal Gammopathy of Undetermined Significance in Relation to Paraproteinemic Keratopathy (An American Ophthalmological Society Thesis).

Authors:  Walter Lisch; Joanna Wasielica-Poslednik; Tero Kivelä; Ursula Schlötzer-Schrehardt; Jens M Rohrbach; Walter Sekundo; Uwe Pleyer; Christina Lisch; Alexander Desuki; Heidi Rossmann; Jayne S Weiss
Journal:  Trans Am Ophthalmol Soc       Date:  2016-08

4.  In vivo confocal microscopic characteristics of crystalline keratopathy in patients with monoclonal gammopathy: report of two cases.

Authors:  Sibel Kocabeyoglu; Mehmet C Mocan; Ibrahim C Haznedaroglu; Aysegul Uner; Enes Uzunosmanoglu; Murat Irkec
Journal:  Indian J Ophthalmol       Date:  2014-09       Impact factor: 1.848

  4 in total
  2 in total

1.  Multimodal imaging in paraproteinemic keratopathy.

Authors:  Neel D Pasricha; Michele D Lee; Gerami D Seitzman
Journal:  Indian J Ophthalmol       Date:  2020-08       Impact factor: 1.848

2.  Recurrence of paraproteinemic keratopathy after penetrating keratoplasty and its assessment with confocal microscopy.

Authors:  J Wasielica-Poslednik; A Gericke; A Desuki; U Schlötzer-Schrehardt; N Pfeiffer; W Lisch
Journal:  Am J Ophthalmol Case Rep       Date:  2018-06-20
  2 in total

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