Literature DB >> 291432

A lod score method for detecting linkage on the X chromosone between a marker locus and a major gene locus for a quantitative.

R D Bock, R Perline.   

Abstract

A sequential lod-score method is proposed for detecting linkage on the X chromosome between a marker locus and the locus of a major gene influencing a quantitative trait, The method uses information from sons of doubly heterozygous mothers. The average number of families required to detect linkage is substantially less than that of the fixed sample-size method proposed by Hill.

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Year:  1979        PMID： 291432     DOI： 10.1007/bf01071297

Source DB:  PubMed          Journal:  Behav Genet        ISSN： 0001-8244            Impact factor:   2.805


  14 in total

1.  Sequential tests for the detection of linkage.

Authors:  N E MORTON
Journal:  Am J Hum Genet       Date:  1955-09       Impact factor: 11.025

2.  A non-parametric test for linkage with a quantitative character.

Authors:  C A Smith
Journal:  Ann Hum Genet       Date:  1975-05       Impact factor: 1.670

3.  Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies.

Authors:  J Ott
Journal:  Am J Hum Genet       Date:  1974-09       Impact factor: 11.025

4.  Linkage between marker loci and those affecting a quantitative trait.

Authors:  A Robertson
Journal:  Behav Genet       Date:  1973-12       Impact factor: 2.805

5.  A general model for the genetic analysis of pedigree data.

Authors:  R C Elston; J Stewart
Journal:  Hum Hered       Date:  1971       Impact factor: 0.444

6.  [Distribution of frequecies, interpretation of genetic determinism of quantitative characteristics and research of "major genes"].

Authors:  P Mérat
Journal:  Biometrics       Date:  1968-06       Impact factor: 2.571

7.  On the detection and estimation of linkage between a locus influencing a quantitative character and a marker locus.

Authors:  S D Jayakar
Journal:  Biometrics       Date:  1970-09       Impact factor: 2.571

8.  Intrafamilial correlations and heritability estimates for spatial ability in a Minnesota sample.

Authors:  M G McGee
Journal:  Behav Genet       Date:  1978-01       Impact factor: 2.805

9.  Heritability estimates and genetic and environmental correlations for the human immunoglobulins G, M, and A.

Authors:  F J Grundbacher
Journal:  Am J Hum Genet       Date:  1974-01       Impact factor: 11.025

10.  The investigation of linkage between a quantitative trait and a marker locus.

Authors:  J K Haseman; R C Elston
Journal:  Behav Genet       Date:  1972-03       Impact factor: 2.805
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