Literature DB >> 29138782

Vasorelaxant activity of twenty-one physiologically relevant (poly)phenolic metabolites on isolated mouse arteries.

E Van Rymenant1, C Grootaert, K Beerens, P W Needs, P A Kroon, A Kerimi, G Williamson, R García-Villalba, A González-Sarrías, F Tomas-Barberan, J Van Camp, J Van de Voorde.   

Abstract

Polyphenols are beneficial for health, but are metabolised after consumption. We compared the vasorelaxant capacity of twenty-one physiologically relevant polyphenol metabolites in isolated mouse arteries. Hesperetin, urolithins and ferulic acid-4-O-sulfate - not their glucuronidated forms or ferulic acid - caused vasorelaxation. Therefore, we advise the use of relevant conjugates in future mechanistic research.

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Year:  2017        PMID: 29138782     DOI: 10.1039/c7fo01273j

Source DB:  PubMed          Journal:  Food Funct        ISSN: 2042-6496            Impact factor:   5.396


  5 in total

1.  Sulfated phenolic acids in plants.

Authors:  Klara Supikova; Andrea Kosinova; Martin Vavrusa; Lucie Koplikova; Anja François; Jiri Pospisil; Marek Zatloukal; Ron Wever; Aloysius Hartog; Jiri Gruz
Journal:  Planta       Date:  2022-05-13       Impact factor: 4.116

2.  The Effects of Anthocyanins and Their Microbial Metabolites on the Expression and Enzyme Activities of Paraoxonase 1, an Important Marker of HDL Function.

Authors:  Hassan T Aboufarrag; Paul W Needs; Gerald Rimbach; Paul A Kroon
Journal:  Nutrients       Date:  2019-11-24       Impact factor: 5.717

3.  An Integrative Pharmacology-Based Strategy to Uncover the Mechanism of Xiong-Pi-Fang in Treating Coronary Heart Disease with Depression.

Authors:  Lihong Zhang; Yu Zhang; Mingdan Zhu; Limin Pei; Fangjun Deng; JinHong Chen; Shaoqiang Zhang; Zidong Cong; Wuxun Du; Xuefeng Xiao
Journal:  Front Pharmacol       Date:  2021-04-01       Impact factor: 5.810

Review 4.  Effect of Gut Microbiota Biotransformation on Dietary Tannins and Human Health Implications.

Authors:  Ibrahim E Sallam; Amr Abdelwareth; Heba Attia; Ramy K Aziz; Masun Nabhan Homsi; Martin von Bergen; Mohamed A Farag
Journal:  Microorganisms       Date:  2021-04-29

5.  Inhibition of 5-Lipoxygenase-Derived Leukotrienes and Hemiketals as a Novel Anti-Inflammatory Mechanism of Urolithins.

Authors:  Juan Antonio Giménez-Bastida; Antonio González-Sarrías; Juan Carlos Espín; Claus Schneider
Journal:  Mol Nutr Food Res       Date:  2020-05-04       Impact factor: 6.575

  5 in total

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