| Literature DB >> 29138197 |
Anjali Shah1, Andrew Judge1,2,3, Antonella Delmestri1, Katherine Edwards1, Nigel K Arden1,2, Daniel Prieto-Alhambra1, Tim A Holt4, Rafael A Pinedo-Villanueva1, Sally Hopewell5, Sarah E Lamb1, Amar Rangan1,6,7, Andrew J Carr1, Gary S Collins1, Jonathan L Rees1.
Abstract
OBJECTIVE: This cohort study evaluates the unknown age-specific and gender-specific incidence of primary shoulder dislocations in the UK.Entities:
Keywords: clinical practice research datalink; cprd; incidence; shoulder dislocation
Mesh:
Year: 2017 PMID: 29138197 PMCID: PMC5695490 DOI: 10.1136/bmjopen-2017-016112
Source DB: PubMed Journal: BMJ Open ISSN: 2044-6055 Impact factor: 2.692
Figure 1Shoulder dislocation exclusion flow chart for patients aged 16–70 years during 1995–2015 within the CPRD, UK. CPRD, Clinical Practice Research Datalink; GP, general practitioner.
Demographic characteristics of patients with shoulder dislocation aged 16–35 years recorded within the CPRD dataset during 1 April 1997–31 March 2015 in England and responders and non-responders to the CPRD GP validation questionnaire
| Demographic characteristic | Whole cohort* | All GP questionnaires* | Responders* | Non-responders* |
| Cohort size | 6046 | 172 | 97 | 75 |
| Gender | ||||
| Men | 4991 (83%) | 137 (80%) | 81 (84%) | 56 (75%) |
| Women | 1055 (17%) | 35 (20%) | 16 (16%) | 19 (25%) |
| Median age, years (IQR) | 24 (20–34) | 24 (20–29) | 24 (20–29) | 24 (19–29) |
| Median BMI, kg/m2 (IQR) | 24 (22–27) | 24 (21–27) | 25 (22–28) | 23 (21–26) |
| Median Charlson Comorbidity Index (IQR) | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) |
| Region | ||||
| East Midlands | 263 (4%) | 0 (0%) | 0 (0%) | 0 (0%) |
| East of England | 673 (11%) | 21 (12%) | 17 (18%) | 4 (5%) |
| London | 695 (12%) | 23 (13%) | 11 (11%) | 12 (16%) |
| North East | 133 (2%) | 4 (2%) | 3 (3%) | 1 (1%) |
| North West | 951 (16%) | 29 (17%) | 13 (13%) | 16 (21%) |
| South Central | 965 (16%) | 32 (19%) | 17 (18%) | 15 (20%) |
| South East Coast | 702 (12%) | 25 (15%) | 12 (12%) | 13 (17%) |
| South West | 743 (12%) | 17 (10%) | 17 (18%) | 0 (0%) |
| West Midlands | 667 (11%) | 15 (9%) | 7 (7%) | 8 (11%) |
| Yorkshire and the Humber | 254 (4%) | 6 (3%) | 0 (0%) | 6 (8%) |
| Index of Multiple Deprivation 2004 | ||||
| Affluent | 1279 (21%) | 53 (31%) | 28 (29%) | 26 (35%) |
| 2 | 1077 (18%) | 35 (20%) | 20 (21%) | 15 (20%) |
| 3 | 958 (16%) | 24 (14%) | 16 (16%) | 8 (11%) |
| 4 | 876 (14%) | 38 (22%) | 19 (20%) | 18 (24%) |
| Deprived | 624 (10%) | 22 (13%) | 14 (14%) | 8 (11%) |
| Missing | 1232 (20%) | 0 (0%) | 0 (0%) | 0 (0%) |
*Number and percentage (%) are presented unless otherwise stated.
BMI, body mass index; CPRD, Clinical Practice Research Datalink; GP, general practitioner.
Validation of shoulder dislocations coded within the CPRD dataset: responses to GP questionnaires (n=95*)
| n | % | |
| GP confirmation of shoulder dislocation | 85 | 89 |
| Patients who had a confirmed ‘primary’ shoulder dislocation | 72 | 76 |
| Patients who had a further dislocation within 2 yearsof the primary dislocation† | 27 | 32 |
| Confirmation that this was a further dislocation episode and not a review of the problem | 21 | 78 |
| Patients with further dislocations that have notbeen coded within CPRD† | 9 | 11 |
*An additional two questionnaires were received from GPs stating that the patient had transferred out of the practice and that no data were available for them. We have omitted these two patients from the denominator used for this table.
†The denominator is 85 because these patients were confirmed to have had a shoulder dislocation and could then potentially have a redislocation.
CPRD, Clinical Practice Research Datalink; GP, general practitioner.
Baseline characteristics of patients with primary shoulder dislocation aged 16–70 years within the Clinical Practice Research Datalink dataset during 1995–2015, UK
| Characteristic | n | % |
| Total | 16 763 | 100 |
| Gender | ||
| Men | 12 148 | 72 |
| Women | 4615 | 28 |
| Age at shoulder dislocation (years) | ||
| 16–20 | 2561 | 15 |
| 21–30 | 4266 | 25 |
| 31–40 | 3021 | 18 |
| 41–70 | 6915 | 41 |
| Body mass index (kg/m2) | ||
| <18.5 | 180 | 1 |
| 18.5–24.9 | 3392 | 20 |
| 25.0–29.9 | 3020 | 18 |
| 30.0–34.9 | 1292 | 8 |
| ≥35.0 | 768 | 5 |
| Missing | 8111 | 48 |
| Smoking | ||
| Non-smoker | 6674 | 40 |
| Current smoker | 3388 | 20 |
| Ex-smoker | 2014 | 12 |
| Missing | 4687 | 28 |
| Drinking | ||
| Current drinker | 6854 | 41 |
| Non-drinker | 1113 | 7 |
| Ex-drinker | 188 | 1 |
| Missing | 8608 | 51 |
| Charlson Comorbidity Index | ||
| 0 | 14 834 | 88 |
| 1 | 950 | 6 |
| 2 | 523 | 3 |
| ≥3 | 456 | 3 |
| Region | ||
| East Midlands | 600 | 4 |
| East of England | 1444 | 9 |
| London | 1484 | 9 |
| North East | 279 | 2 |
| North West | 2071 | 12 |
| Northern Ireland | 602 | 4 |
| Scotland | 1626 | 10 |
| South Central | 2005 | 12 |
| South East Coast | 1572 | 9 |
| South West | 1462 | 9 |
| Wales | 1591 | 9 |
| West Midlands | 1470 | 9 |
| Yorkshire and the Humber | 557 | 3 |
| Index of Multiple Deprivation 2004 (quintile of deprivation) | ||
| Affluent | 2790 | 17 |
| 2 | 2345 | 14 |
| 3 | 2001 | 12 |
| 4 | 1793 | 11 |
| Deprived | 1309 | 8 |
| Missing | 6525 | 39 |
Figure 2Percentage of patients with primary shoulder dislocation by age (16–70 years) and gender recorded within the Clinical Practice Research Datalink during 1995–2015, UK. Blue bars represent male patients, and red bars represent female patients. 95% CIs are included in this figure, but they are so close to the main data points that they cannot be seen.
The number, incidence rates and incidence rate ratios of primary shoulder dislocation by age and gender within the Clinical Practice Research Datalink dataset during 1995–2015, UK
| Demographic category | n | Person-years* | Incidence rate† | 95% CI | Demographic comparison | Incidence rate ratio | 95% CI | P value |
| Gender | ||||||||
| Male | 12 148 | 30 074 078 | 40.4 | 40.4–40.4 | Male versus female | 2.60 | 2.52–2.69 | <0.001 |
| Female | 4615 | 29 741 559 | 15.5 | 15.5–15.5 | ||||
| Age (years) | ||||||||
| 16–20 | 2561 | 5 245 428 | 48.8 | 48.8–48.9 | ||||
| 21–30 | 4266 | 11 006 586 | 38.8 | 38.7–38.8 | 16–20 vs 21–30 | 1.26 | 1.20–1.32 | <0.001 |
| 31–40 | 3021 | 12 362 061 | 24.4 | 24.4–24.5 | 16–20 vs 31–40 | 2.00 | 1.90–2.11 | <0.001 |
| 41–50 | 2472 | 12 244 890 | 20.2 | 20.2–20.2 | 16–20 vs 41–50 | 2.42 | 2.29–2.56 | <0.001 |
| 51–60 | 2091 | 10 583 309 | 19.8 | 19.7–19.8 | 16–20 vs 51–60 | 2.47 | 2.33–2.62 | <0.001 |
| 61–70 | 2352 | 8 373 363 | 28.1 | 28.1–28.1 | 16–20 vs 61–70 | 1.74 | 1.64–1.84 | <0.001 |
| Age, gender (male) | ||||||||
| 16–20 | 2137 | 2 653 062 | 80.5 | 80.5–80.6 | ||||
| 21–30 | 3588 | 5 463 830 | 65.7 | 65.6–65.7 | 16–20 vs 21–30 | 1.23 | 1.16–1.29 | <0.001 |
| 31–40 | 2316 | 6 265 348 | 37.0 | 36.9–37.0 | 16–20 vs 31–40 | 2.18 | 2.05–2.31 | <0.001 |
| 41–50 | 1733 | 6 243 377 | 27.8 | 27.7–27.8 | 16–20 vs 41–50 | 2.90 | 2.72–3.09 | <0.001 |
| 51–60 | 1244 | 5 342 095 | 23.3 | 23.3–23.3 | 16–20 vs 51–60 | 3.46 | 3.22–3.71 | <0.001 |
| 61–70 | 1130 | 4 106 366 | 27.5 | 27.5–27.5 | 16–20 vs 61–70 | 2.93 | 2.72–3.15 | <0.001 |
| Age, gender (female) | ||||||||
| 16–20 | 424 | 2 592 366 | 16.4 | 16.3–16.4 | ||||
| 21–30 | 678 | 5 542 756 | 12.2 | 12.2–12.2 | 16–20 vs 21–30 | 1.34 | 1.18–1.51 | <0.001 |
| 31–40 | 705 | 6 069 714 | 11.6 | 11.6–11.6 | 16–20 vs 31–40 | 1.41 | 1.25–1.60 | <0.001 |
| 41–50 | 739 | 6 001 514 | 12.3 | 12.3–12.3 | 16–20 vs 41–50 | 1.33 | 1.18–1.50 | <0.001 |
| 51–60 | 847 | 5 241 214 | 16.2 | 16.1–16.2 | 16–20 vs 51–60 | 1.01 | 0.90–1.14 | 0.840 |
| 61–70 | 1222 | 4 266 996 | 28.6 | 28.6–28.7 | 16–20 vs 61–70 | 0.57 | 0.51–0.64 | <0.001 |
| Age, gender (male vs female) | ||||||||
| 16–20 vs 16–20 | 4.92 | 4.44–5.47 | <0.001 | |||||
| 21–30 vs 21–30 | 5.37 | 4.95–5.83 | <0.001 | |||||
| 31–40 vs 31–40 | 3.20 | 2.94–3.48 | <0.001 | |||||
| 41–50 vs 41–50 | 2.25 | 2.07–2.46 | <0.001 | |||||
| 51–60 vs 51–60 | 1.44 | 1.32–1.57 | <0.001 | |||||
| 61–70 vs 61–70 | 0.96 | 0.89–1.04 | 0.334 |
*Person-years used as the denominator for incidence rates, as obtained for patients aged 16–70 years during 1995–2015 in the CPRD dataset.
†The incidence rate per 100 000 person-years.
CPRD, Clinical Practice Research Datalink.
Figure 3Shoulder dislocation incidence rates by age and gender during 1995–2015 in the UK, using data from the Clinical Practice Research Datalink.