BACKGROUND: This retrospective study is designed to evaluate factors affecting survival in a population of patients receiving pulmonary metastasectomy after gynecologic cancers. METHODS: Nineteen patients with isolated lung metastases (one or two) were surgically treated with R0 resection. Four of them underwent lobectomies. RESULTS: Six patients (31.6%) received adjuvant therapy and 11 (58%) experienced recurrences after metastasectomy. Five- and ten-year survival were 40.9% and 31.4%, respectively. Five-year survival in patients receiving adjuvant therapy was 52.4%. At multivariate analysis factors negatively influencing survival were a disease-free interval (DFI) of less than 24 months and recurrence after pulmonary metastasectomy. CONCLUSIONS: Pulmonary resection for metastatic gynecologic cancer is feasible and effective; adequate selection of patients is mandatory to achieve satisfactory results and long-term survival.
BACKGROUND: This retrospective study is designed to evaluate factors affecting survival in a population of patients receiving pulmonary metastasectomy after gynecologic cancers. METHODS: Nineteen patients with isolated lung metastases (one or two) were surgically treated with R0 resection. Four of them underwent lobectomies. RESULTS: Six patients (31.6%) received adjuvant therapy and 11 (58%) experienced recurrences after metastasectomy. Five- and ten-year survival were 40.9% and 31.4%, respectively. Five-year survival in patients receiving adjuvant therapy was 52.4%. At multivariate analysis factors negatively influencing survival were a disease-free interval (DFI) of less than 24 months and recurrence after pulmonary metastasectomy. CONCLUSIONS: Pulmonary resection for metastatic gynecologic cancer is feasible and effective; adequate selection of patients is mandatory to achieve satisfactory results and long-term survival.
Authors: J C Lin; R J Wiechmann; M F Szwerc; S R Hazelrigg; P F Ferson; K S Naunheim; R J Keenan; A P Yim; E Rendina; T DeGiacomo; G F Coloni; F Venuta; R S Macherey; S Bartley; R J Landreneau Journal: Surgery Date: 1999-10 Impact factor: 3.982
Authors: P Girard; L Spaggiari; P Baldeyrou; T Le Chevalier; A Le Cesne; B Escudier; M Filaire; D Grunenwald Journal: Eur J Cardiothorac Surg Date: 1997-09 Impact factor: 4.191
Authors: E Sun Paik; Aera Yoon; Yoo Young Lee; Tae Joong Kim; Jeong Won Lee; Duk Soo Bae; Byoung Gie Kim Journal: J Gynecol Oncol Date: 2015-07-17 Impact factor: 4.401