| Literature DB >> 29116784 |
Gabriel J Lovinger1, James P Morken1.
Abstract
The catalytic enantioselective conjunctive coupling of C(sp3) electrophiles can be accomplished with Ni catalysis. The enantioselectivity of the reaction is dependent on reaction mechanism with many substrates able to engage in an asymmetric process with Pybox-Ni complexes, whereas other substrates provide racemic product mixtures. The link between substrate structure and selectivity is addressed.Entities:
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Year: 2017 PMID： 29116784 PMCID： PMC6598435 DOI： 10.1021/jacs.7b10519
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419