Literature DB >> 29111990

Cancer Risk Associated With Exposure to Bitumen and Bitumen Fumes: An Updated Systematic Review and Meta-Analysis.

Kenneth A Mundt1, Linda D Dell, Lori Crawford, Sonja N Sax, Paolo Boffetta.   

Abstract

OBJECTIVE: To evaluate whether cancer risks are increased among bitumen (asphalt) workers.
METHODS: Systematic review and meta-analysis of cancer risks (lung, upper aerodigestive tract (UADT), esophagus, bladder, kidney, stomach, and skin) and bitumen exposure. Certainty in the epidemiological evidence that bitumen-exposed workers experience increased cancer risks was rated using Grading of Recommendations Assessment, Development and Evaluation criteria.
RESULTS: After excluding lower-quality studies, lung cancer risks were not increased among bitumen-exposed workers (meta-relative risk [RR] 0.94, 95% CI 0.74 to 1.20, eight studies). Increased risks of UADT and stomach cancers were observed (meta-RR 1.31, 95% CI 1.03 to 1.67, 10 studies and meta-RR 1.29, 95% CI 1.03 to 1.62, seven studies, respectively).
CONCLUSIONS: Except for lung cancer, evidence for increased cancer risks among bitumen-exposed workers was judged to be of low certainty, due to inadequate exposure characterization and unmeasured confounders (coal tar exposure, smoking, and alcohol consumption).

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Year:  2018        PMID: 29111990     DOI: 10.1097/JOM.0000000000001202

Source DB:  PubMed          Journal:  J Occup Environ Med        ISSN: 1076-2752            Impact factor:   2.162


  3 in total

1.  Association between serum zinc levels and lung cancer: a meta-analysis of observational studies.

Authors:  Ying Wang; Zhengyi Sun; Aipeng Li; Yongsheng Zhang
Journal:  World J Surg Oncol       Date:  2019-05-06       Impact factor: 2.754

2.  Occupational Exposures and Esophageal Cancer: Prog Study.

Authors:  Annabelle Gressier; Greta Gourier; Jean-Philippe Metges; Jean-Dominique Dewitte; Brice Loddé; David Lucas
Journal:  Int J Environ Res Public Health       Date:  2022-08-09       Impact factor: 4.614

Review 3.  Sample Preparation and Analytical Methods for Identifying Organic Compounds in Bituminous Emissions.

Authors:  Zachary Deller; Subashani Maniam; Filippo Giustozzi
Journal:  Molecules       Date:  2022-08-09       Impact factor: 4.927

  3 in total

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