Karen A Ertel1, Tianyi Huang2, Sheryl L Rifas-Shiman3, Ken Kleinman4, Janet Rich-Edwards5, Emily Oken3, Tamarra James-Todd5. 1. Department of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst. Electronic address: kertel@schoolph.umass.edu. 2. Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA. 3. Obesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA. 4. Department of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst. 5. Division of Women's Health, Department of Medicine, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA; Departments of Environmental Health and Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.
Abstract
PURPOSE: Prepregnancy obesity and weight changes accompanying pregnancy (gestational weight gain and postpartum weight retention) may be associated with risk of maternal depressive symptoms during pregnancy and in the postpartum. The few studies that have examined these relationships report conflicting findings. METHODS: We studied pregnant (n = 2112) and postpartum (n = 1686) women enrolled in Project Viva. We used self-reported prepregnancy and postpartum weight and measured prenatal weight to calculate prepregnancy body mass index (BMI), gestational weight gain (GWG), and postpartum weight retention at 6 months after birth. We assessed elevated depressive symptoms (EDS) with the Edinburgh Postnatal Depression Scale (≥13 on 0-30 scale) at midpregnancy and 6 months postpartum. We used logistic regression to estimate the odds of prenatal and postpartum EDS in relation to prepregnancy BMI, GWG, and postpartum weight retention. RESULTS: A total of 214 (10%) participants experienced prenatal EDS and 151 (9%) postpartum EDS. Neither prepregnancy BMI nor GWG was associated with prenatal EDS. Prepregnancy obesity (BMI ≥ 30 kg per m2) was associated with higher odds of postpartum EDS (odds ratio = 1.69, 95% confidence interval, 1.01-2.83) compared to normal prepregnancy weight in a model adjusted for age, race/ethnicity, nativity, education, marital status, household income, parity, pregnancy intention, and smoking. CONCLUSIONS: Prepregnancy obesity is associated with elevated depressive symptoms in the postpartum period. Given the current obesity epidemic in the US and the consequences of perinatal depression, additional prevention and screening efforts in this population may be warranted.
PURPOSE:Prepregnancy obesity and weight changes accompanying pregnancy (gestational weight gain and postpartum weight retention) may be associated with risk of maternal depressive symptoms during pregnancy and in the postpartum. The few studies that have examined these relationships report conflicting findings. METHODS: We studied pregnant (n = 2112) and postpartum (n = 1686) women enrolled in Project Viva. We used self-reported prepregnancy and postpartum weight and measured prenatal weight to calculate prepregnancy body mass index (BMI), gestational weight gain (GWG), and postpartum weight retention at 6 months after birth. We assessed elevated depressive symptoms (EDS) with the Edinburgh Postnatal Depression Scale (≥13 on 0-30 scale) at midpregnancy and 6 months postpartum. We used logistic regression to estimate the odds of prenatal and postpartum EDS in relation to prepregnancy BMI, GWG, and postpartum weight retention. RESULTS: A total of 214 (10%) participants experienced prenatal EDS and 151 (9%) postpartum EDS. Neither prepregnancy BMI nor GWG was associated with prenatal EDS. Prepregnancy obesity (BMI ≥ 30 kg per m2) was associated with higher odds of postpartum EDS (odds ratio = 1.69, 95% confidence interval, 1.01-2.83) compared to normal prepregnancy weight in a model adjusted for age, race/ethnicity, nativity, education, marital status, household income, parity, pregnancy intention, and smoking. CONCLUSIONS:Prepregnancy obesity is associated with elevated depressive symptoms in the postpartum period. Given the current obesity epidemic in the US and the consequences of perinatal depression, additional prevention and screening efforts in this population may be warranted.
Authors: Emily Oken; Andrea A Baccarelli; Diane R Gold; Ken P Kleinman; Augusto A Litonjua; Dawn De Meo; Janet W Rich-Edwards; Sheryl L Rifas-Shiman; Sharon Sagiv; Elsie M Taveras; Scott T Weiss; Mandy B Belfort; Heather H Burris; Carlos A Camargo; Susanna Y Huh; Christos Mantzoros; Margaret G Parker; Matthew W Gillman Journal: Int J Epidemiol Date: 2014-03-16 Impact factor: 7.196
Authors: Angela C Incollingo Rodriguez; Elissa S Epel; Megan L White; Erin C Standen; Jonathan R Seckl; A Janet Tomiyama Journal: Psychoneuroendocrinology Date: 2015-08-21 Impact factor: 4.905
Authors: Floriana S Luppino; Leonore M de Wit; Paul F Bouvy; Theo Stijnen; Pim Cuijpers; Brenda W J H Penninx; Frans G Zitman Journal: Arch Gen Psychiatry Date: 2010-03
Authors: Hashem Salarzadeh Jenatabadi; Nadia Samsudin; Che Wan Jasimah Bt Wan Mohamed Radzi Journal: BMC Public Health Date: 2021-01-27 Impact factor: 3.295
Authors: Karen Matvienko-Sikar; Kate O' Neill; Abigail Fraser; Catherine Hayes; Laura Howe; Anja C Huizink; Patricia M Kearney; Ali Khashan; Sarah A Redsell; Linda M O'Keeffe Journal: BMJ Open Date: 2021-12-15 Impact factor: 2.692