Literature DB >> 29102742

Gene-environment interactions between education and body mass: Evidence from the UK and Finland.

Vikesh Amin1, Petri Böckerman2, Jutta Viinikainen3, Melissa C Smart4, Yanchun Bao5, Meena Kumari6, Niina Pitkänen7, Terho Lehtimäki8, Olli Raitakari9, Jaakko Pehkonen10.   

Abstract

More education is associated with a lower body mass index (BMI) and likelihood of being overweight. However, since a large proportion of the variation in body mass is due to genetic makeup, it has been hypothesized that education may moderate the genetic risk. We estimate main associations between (i) education, (ii) genetic risk, and (iii) interactions between education and genetic risk on BMI and the probability of being overweight in the UK and Finland. The estimates show that education is negatively associated with BMI and overweightness, and genetic risk is positively associated. However, the interactions between education and genetic risk are small and statistically insignificant.
Copyright © 2017 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Education; Gene-environment interactions; Obesity

Mesh:

Year:  2017        PMID: 29102742     DOI: 10.1016/j.socscimed.2017.10.027

Source DB:  PubMed          Journal:  Soc Sci Med        ISSN: 0277-9536            Impact factor:   4.634


  6 in total

1.  Does education attenuate the genetic risk of obesity? Evidence from U.K. Twins.

Authors:  Vikesh Amin; Paul Dunn; Tim Spector
Journal:  Econ Hum Biol       Date:  2018-09-13       Impact factor: 2.184

2.  A genetic sum score of risk alleles associated with body mass index interacts with socioeconomic position in the Heinz Nixdorf Recall Study.

Authors:  Mirjam Frank; Nico Dragano; Marina Arendt; Andreas J Forstner; Markus M Nöthen; Susanne Moebus; Raimund Erbel; Karl-Heinz Jöckel; Börge Schmidt
Journal:  PLoS One       Date:  2019-08-23       Impact factor: 3.240

3.  Gene-environment dependencies lead to collider bias in models with polygenic scores.

Authors:  Evelina T Akimova; Richard Breen; David M Brazel; Melinda C Mills
Journal:  Sci Rep       Date:  2021-05-04       Impact factor: 4.379

4.  Educational attainment as a modifier for the effect of polygenic scores for cardiovascular risk factors: cross-sectional and prospective analysis of UK Biobank.

Authors:  Alice R Carter; Sean Harrison; Dipender Gill; George Davey Smith; Amy E Taylor; Laura D Howe; Neil M Davies
Journal:  Int J Epidemiol       Date:  2022-06-13       Impact factor: 9.685

5.  Education can reduce health differences related to genetic risk of obesity.

Authors:  Silvia H Barcellos; Leandro S Carvalho; Patrick Turley
Journal:  Proc Natl Acad Sci U S A       Date:  2018-10-02       Impact factor: 11.205

6.  Associations of Genetic Factors, Educational Attainment, and Their Interaction With Kidney Function Outcomes.

Authors:  Chris H L Thio; Sander K R van Zon; Peter J van der Most; Harold Snieder; Ute Bültmann; Ron T Gansevoort
Journal:  Am J Epidemiol       Date:  2021-05-04       Impact factor: 4.897

  6 in total

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