Literature DB >> 29102083

Cracking the Chaperone Code: Cellular Roles for Hsp70 Phosphorylation.

Andrew W Truman1.   

Abstract

Heat shock protein 70 (Hsp70) is a molecular chaperone required for protein folding, cell viability, and cancer cell proliferation. Recent studies suggest that Hsp70 phosphorylation regulates important cellular processes, such as cell cycle progression, apoptosis, protein degradation, and resistance to anticancer therapeutics. Published by Elsevier Ltd.

Entities:  

Keywords:  Hsp70; cancer; chaperones; kinases; phosphorylation

Mesh：

Substances：

Year:  2017        PMID： 29102083      PMCID： PMC5701876          DOI： 10.1016/j.tibs.2017.10.002

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  12 in total

1.  C-terminal phosphorylation of Hsp70 and Hsp90 regulates alternate binding to co-chaperones CHIP and HOP to determine cellular protein folding/degradation balances.

Authors:  P Muller; E Ruckova; P Halada; P J Coates; R Hrstka; D P Lane; B Vojtesek
Journal:  Oncogene       Date:  2012-07-23       Impact factor: 9.867

Review 2.  The HSP70 chaperone machinery: J proteins as drivers of functional specificity.

Authors:  Harm H Kampinga; Elizabeth A Craig
Journal:  Nat Rev Mol Cell Biol       Date:  2010-08       Impact factor: 94.444

3.  Identification and characterization of a 66-68-kDa protein as a methotrexate-binding protein in murine leukemia L1210 cells.

Authors:  Tuoen Liu; Allison Dean; Saint Ashwini; Peter P Sheridan; Alok Bhushan; James C K Lai; Shousong Cao; Christopher K Daniels
Journal:  Cell Stress Chaperones       Date:  2012-10-23       Impact factor: 3.667

4.  Specific Binding of Tetratricopeptide Repeat Proteins to Heat Shock Protein 70 (Hsp70) and Heat Shock Protein 90 (Hsp90) Is Regulated by Affinity and Phosphorylation.

Authors:  Victoria A Assimon; Daniel R Southworth; Jason E Gestwicki
Journal:  Biochemistry       Date:  2015-11-25       Impact factor: 3.162

5.  HSP70 colocalizes with PLK1 at the centrosome and disturbs spindle dynamics in cells arrested in mitosis by arsenic trioxide.

Authors:  Yu-Ju Chen; Kuo-Chu Lai; Hsiao-Hui Kuo; Lu-Ping Chow; Ling-Huei Yih; Te-Chang Lee
Journal:  Arch Toxicol       Date:  2014-03-13       Impact factor: 5.153

6.  Systematic functional prioritization of protein posttranslational modifications.

Authors:  Pedro Beltrao; Véronique Albanèse; Lillian R Kenner; Danielle L Swaney; Alma Burlingame; Judit Villén; Wendell A Lim; James S Fraser; Judith Frydman; Nevan J Krogan
Journal:  Cell       Date:  2012-07-20       Impact factor: 41.582

7.  Anchoring of both PKA-RIIα and 14-3-3θ regulates retinoic acid induced 16 mediated phosphorylation of heat shock protein 70.

Authors:  Cui-Ling Ding; Gang Xu; Hai-Lin Tang; Shi-Ying Zhu; Lan-Juan Zhao; Hao Ren; Ping Zhao; Zhong-Tian Qi; Wen Wang
Journal:  Oncotarget       Date:  2015-06-20

8.  Hsp70 forms antiparallel dimers stabilized by post-translational modifications to position clients for transfer to Hsp90.

Authors:  Nina Morgner; Carla Schmidt; Victoria Beilsten-Edmands; Ima-Obong Ebong; Nisha A Patel; Eugenia M Clerico; Elaine Kirschke; Soumya Daturpalli; Sophie E Jackson; David Agard; Carol V Robinson
Journal:  Cell Rep       Date:  2015-04-23       Impact factor: 9.423

9.  Hsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression.

Authors:  Laura O'Regan; Josephina Sampson; Mark W Richards; Axel Knebel; Daniel Roth; Fiona E Hood; Anne Straube; Stephen J Royle; Richard Bayliss; Andrew M Fry
Journal:  J Cell Biol       Date:  2015-05-04       Impact factor: 10.539

10.  CDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progression.

Authors:  Andrew W Truman; Kolbrun Kristjansdottir; Donald Wolfgeher; Naushaba Hasin; Sigrun Polier; Hong Zhang; Sarah Perrett; Chrisostomos Prodromou; Gary W Jones; Stephen J Kron
Journal:  Cell       Date:  2012-12-07       Impact factor: 41.582
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  13 in total

Review 1.  Post-translational modifications of Hsp90 and translating the chaperone code.

Authors:  Sarah J Backe; Rebecca A Sager; Mark R Woodford; Alan M Makedon; Mehdi Mollapour
Journal:  J Biol Chem       Date:  2020-06-11       Impact factor: 5.157

2.  Dynamic remodeling of the interactomes of Nematostella vectensis Hsp70 isoforms under heat shock.

Authors:  Laura E Knighton; Shawn J Waller; Owen Strom; Donald Wolfgeher; Adam M Reitzel; Andrew W Truman
Journal:  J Proteomics       Date:  2019-06-21       Impact factor: 4.044

Review 3.  Not quite the SSAme: unique roles for the yeast cytosolic Hsp70s.

Authors:  Sarah K Lotz; Laura E Knighton; Gary W Jones; Andrew W Truman
Journal:  Curr Genet       Date:  2019-04-24       Impact factor: 3.886

4.  Heat shock proteins as biomarkers of lung cancer.

Authors:  Sonam Mittal; Maitreyi S Rajala
Journal:  Cancer Biol Ther       Date:  2020-03-31       Impact factor: 4.742

5.  Host expression system modulates recombinant Hsp70 activity through post-translational modifications.

Authors:  Mauricio M Rigo; Thiago J Borges; Benjamin J Lang; Ayesha Murshid; Donald Wolfgeher; Stuart K Calderwood; Andrew W Truman; Cristina Bonorino
Journal:  FEBS J       Date:  2020-03-06       Impact factor: 5.542

Review 6.  Post-translational modifications of Hsp70 family proteins: Expanding the chaperone code.

Authors:  Corey M Porter; Andrew W Truman; Matthias C Truttmann
Journal:  J Biol Chem       Date:  2020-06-09       Impact factor: 5.157

7.  Characterizing functional differences in sea anemone Hsp70 isoforms using budding yeast.

Authors:  Shawn J Waller; Laura E Knighton; Lenora M Crabtree; Abigail L Perkins; Adam M Reitzel; Andrew W Truman
Journal:  Cell Stress Chaperones       Date:  2018-04-25       Impact factor: 3.667

Review 8.  The functions and regulation of heat shock proteins; key orchestrators of proteostasis and the heat shock response.

Authors:  Benjamin J Lang; Martin E Guerrero; Thomas L Prince; Yuka Okusha; Cristina Bonorino; Stuart K Calderwood
Journal:  Arch Toxicol       Date:  2021-05-18       Impact factor: 5.153

Review 9.  Comprehending the Proteomic Landscape of Ovarian Cancer: A Road to the Discovery of Disease Biomarkers.

Authors:  Shuvolina Mukherjee; Karin Sundfeldt; Carl A K Borrebaeck; Magnus E Jakobsson
Journal:  Proteomes       Date:  2021-05-25

10.  HSF3 and Hsp70 Expression during Post-Hatch Cold Stress in Broiler Chickens Subjected to Embryonic Thermal Manipulation.

Authors:  Amneh H Tarkhan; Khaled M M Saleh; Mohammad Borhan Al-Zghoul
Journal:  Vet Sci       Date:  2020-04-22
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