Literature DB >> 29086233

New cyclic sulfides, garlicnins I2, M, N, and O, from Allium sativum.

Toshihiro Nohara1, Masateru Ono2, Naho Nishioka2, Fuka Masuda2, Yukio Fujiwara3, Tsuyoshi Ikeda4, Daisuke Nakano5, Junei Kinjo5.   

Abstract

One atypical thiolane-type sulfide, garlicnin I2 (1), two 3,4-dimethylthiolane-type sulfides, garlicnins M (2) and N (3), and one thiabicyclic-type sulfide, garlicnin O (4), were isolated from the acetone extracts of Chinese garlic bulbs, Allium sativum and their structures were characterized. Hypothetical pathways for the production of the respective sulfides were discussed.

Entities:  

Keywords:  3,4-Dimethylthiolane-type; Allium sativum; Atypical thiolane-type; Garlicnin M; Garlicnin O; Thiabicyclic-type

Mesh：

Substances：

Year:  2017        PMID： 29086233     DOI： 10.1007/s11418-017-1133-2

Source DB:  PubMed          Journal:  J Nat Med        ISSN： 1340-3443            Impact factor:   2.343


  20 in total

Review 1.  Alternative activation of macrophages.

Authors:  Siamon Gordon
Journal:  Nat Rev Immunol       Date:  2003-01       Impact factor: 53.106

2.  Onionin A from Allium cepa inhibits macrophage activation.

Authors:  Mona El-Aasr; Yukio Fujiwara; Motohiro Takeya; Tsuyoshi Ikeda; Sachiko Tsukamoto; Masateru Ono; Daisuke Nakano; Masafumi Okawa; Junei Kinjo; Hitoshi Yoshimitsu; Toshihiro Nohara
Journal:  J Nat Prod       Date:  2010-07-23       Impact factor: 4.050

3.  Garlicnins B(1), C(1), and D, from the fraction regulating macrophage activation of Allium sativum.

Authors:  Toshihiro Nohara; Yuka Kiyota; Toyonobu Sakamoto; Hideyuki Manabe; Masateru Ono; Tsuyoshi Ikeda; Yukio Fujiwara; Daisuke Nakano; Junei Kinjo
Journal:  Chem Pharm Bull (Tokyo)       Date:  2012       Impact factor: 1.645

Review 4.  Regulation of macrophage function in tumors: the multifaceted role of NF-kappaB.

Authors:  Thorsten Hagemann; Subhra K Biswas; Toby Lawrence; Antonio Sica; Claire E Lewis
Journal:  Blood       Date:  2009-01-26       Impact factor: 22.113

Review 5.  Clarifying the real bioactive constituents of garlic.

Authors:  Harunobu Amagase
Journal:  J Nutr       Date:  2006-03       Impact factor: 4.798

6.  Cyclic sulfoxides garlicnins B2, B3, B4, C2, and C3 from Allium sativum.

Authors:  Toshihiro Nohara; Yukio Fujiwara; Tsuyoshi Ikeda; Kohtaro Murakami; Masateru Ono; Daisuke Nakano; Junei Kinjo
Journal:  Chem Pharm Bull (Tokyo)       Date:  2013       Impact factor: 1.645

Review 7.  Macrophage polarization in tumour progression.

Authors:  Antonio Sica; Paola Larghi; Alessandra Mancino; Luca Rubino; Chiara Porta; Maria Grazia Totaro; Monica Rimoldi; Subhra Kumar Biswas; Paola Allavena; Alberto Mantovani
Journal:  Semin Cancer Biol       Date:  2008-03-26       Impact factor: 15.707

Review 8.  Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy.

Authors:  Antonio Sica; Tiziana Schioppa; Alberto Mantovani; Paola Allavena
Journal:  Eur J Cancer       Date:  2006-03-07       Impact factor: 9.162

9.  Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas.

Authors:  Y Komohara; K Ohnishi; J Kuratsu; M Takeya
Journal:  J Pathol       Date:  2008-09       Impact factor: 7.996

Review 10.  Tumor-associated macrophages and dendritic cells as prototypic type II polarized myeloid populations.

Authors:  Alberto Mantovani; Tiziana Schioppa; Subhra K Biswas; Federica Marchesi; Paola Allavena; Antonio Sica
Journal:  Tumori       Date:  2003 Sep-Oct
View more
  1 in total

Review 1.  Thiolane-type sulfides from garlic, onion, and Welsh onion.

Authors:  Toshihiro Nohara; Yukio Fujiwara; Mona El-Aasr; Tsuyoshi Ikeda; Masateru Ono; Daisuke Nakano; Junei Kinjo
Journal:  J Nat Med       Date:  2021-06-03       Impact factor: 2.343
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.