M V Malfertheiner1, L M Broman2, M Belliato3, A Venti3, A Bader4, F S Taccone4, M Di Nardo5, G Maj6, F Pappalardo6. 1. Department of Internal Medicine II, Cardiology and Pneumology, Center for Sleep Medicine, University Medical Center Regensburg, Regensburg, Germany. 2. ECMO Centre Karolinska, Department of Pediatric Perioperative Medicine and Intensive Care, Karolinska University Hospital; and Department of Physiology and Pharamacology, Karolinska Institutet, Stockholm, Sweden. 3. UOC Anestesia e Rianimazione, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy. 4. Department of Intensive Care, Hôpital Erasme, Université Libre de Bruxelles, Belgium. 5. Pediatric Intensive Care Unit, Children's Hospital Bambino Gesù, Rome, Italy. 6. Department of Cardiothoracic Anesthesia and Intensive Care, San Raffaele Scientific Institute, Milan, Italy.
Abstract
OBJECTIVE: To investigate contemporary clinical practice in the management of venovenous (VV) extracorporeal membrane oxygenation (ECMO) in critically ill patients with bacterial pneumonia. METHODS: In this multicentre retrospective study, 48 patients with severe respiratory failure due to bacterial pneumonia receiving VV ECMO therapy in five experienced European ECMO centres were included. Ventilator and ECMO settings were analysed. RESULTS: Ventilator settings showed great variability between participating centres, particularly relating to positive end-expiratory pressure, peak inspiratory pressure and driving pressure. Different strategies in cannulation, ECMO setting and weaning procedures were also observed. CONCLUSION: There is great diversity in management modalities for ventilator and ECMO settings for patients with bacterial pneumonia. Our study emphasises the lack of clinical consensus in VV ECMO management.
OBJECTIVE: To investigate contemporary clinical practice in the management of venovenous (VV) extracorporeal membrane oxygenation (ECMO) in critically illpatients with bacterial pneumonia. METHODS: In this multicentre retrospective study, 48 patients with severe respiratory failure due to bacterial pneumonia receiving VV ECMO therapy in five experienced European ECMO centres were included. Ventilator and ECMO settings were analysed. RESULTS: Ventilator settings showed great variability between participating centres, particularly relating to positive end-expiratory pressure, peak inspiratory pressure and driving pressure. Different strategies in cannulation, ECMO setting and weaning procedures were also observed. CONCLUSION: There is great diversity in management modalities for ventilator and ECMO settings for patients with bacterial pneumonia. Our study emphasises the lack of clinical consensus in VV ECMO management.
Authors: Katrina K Ki; Margaret R Passmore; Chris H H Chan; Maximilian V Malfertheiner; Jonathon P Fanning; Mahé Bouquet; Jonathan E Millar; John F Fraser; Jacky Y Suen Journal: Intensive Care Med Exp Date: 2019-08-20
Authors: Imad R Khan; Yang Gu; Benjamin P George; Laura Malone; Kyle S Conway; Fabienne Francois; Jack Donlon; Nadim Quazi; Ashwin Reddi; Cheng-Ying Ho; Daniel L Herr; Mahlon D Johnson; Gunjan Y Parikh Journal: Neurology Date: 2021-01-20 Impact factor: 9.910