Sara M Lippa1, Tracey A Brickell, Jason M Bailie, Louis M French, Jan E Kennedy, Rael T Lange. 1. Defense and Veterans Brain Injury Center, Silver Spring, Maryland (Drs Lippa, Brickell, Bailie, French, Kennedy, and Lange); Walter Reed National Military Medical Center, Bethesda, Maryland (Drs Lippa, Brickell, French, and Lange); National Intrepid Center of Excellence, Bethesda, Maryland (Drs Lippa, Brickell, French, and Lange); Uniformed Services University of the Health Sciences, Bethesda, Maryland (Drs Brickell and French); Naval Hospital Camp Pendleton, Oceanside, California (Dr Bailie); Center for Neuroscience and Regenerative Medicine, Bethesda, Maryland (Dr French); San Antonio Military Medical Center, San Antonio, Texas (Dr Kennedy); and The University of British Columbia, Vancouver, British Columbia, Canada (Dr Lange).
Abstract
OBJECTIVE: Examine effects of diagnostically relevant posttraumatic stress disorder (PTSD) symptoms, mild traumatic brain injury (TBI) severity, and associated bodily injury severity on postconcussion symptom reporting in female service members (SM) compared with a matched sample of male SM. SETTING: Six US military medical treatment facilities. PARTICIPANTS: A total of 158 SM (79 females, 79 males) evaluated within 30 months after mild TBI. Men and women were matched by age, days postinjury, PTSD symptom status, mild TBI severity, and bodily injury severity. All passed a measure of symptom validity. DESIGN: Compare reported postconcussion symptoms for men and women stratified by PTSD diagnostic symptoms (present/absent), mild TBI severity (alteration of consciousness/loss of consciousness), and bodily injury severity (mild/moderate-severe). MAIN MEASURES: Neurobehavioral Symptom Inventory, PTSD Checklist, Abbreviated Injury Scale. RESULTS: Overall postconcussion symptom reporting increased with PTSD but did not significantly differ based on severity of mild TBI or associated bodily injury. Females reported more somatosensory and/or vestibular symptoms than males under some circumstances. Females in the PTSD-Present group, Alteration of Consciousness Only group, and Moderate-Severe Bodily Injury group reported more somatosensory symptoms than males in those groups. Females in the Alteration of Consciousness Only group and Minor Bodily Injury group reported more vestibular symptoms than males in those groups. CONCLUSION: Diagnostically relevant PTSD symptoms, mild TBI severity, and bodily injury severity differentially impact somatosensory and vestibular postconcussion symptom reporting for male and female SM after mild TBI. Controlling for PTSD and symptom validity resulted in fewer gender-based differences in postconcussive symptoms than previously demonstrated in the literature.
OBJECTIVE: Examine effects of diagnostically relevant posttraumatic stress disorder (PTSD) symptoms, mild traumatic brain injury (TBI) severity, and associated bodily injury severity on postconcussion symptom reporting in female service members (SM) compared with a matched sample of male SM. SETTING: Six US military medical treatment facilities. PARTICIPANTS: A total of 158 SM (79 females, 79 males) evaluated within 30 months after mild TBI. Men and women were matched by age, days postinjury, PTSD symptom status, mild TBI severity, and bodily injury severity. All passed a measure of symptom validity. DESIGN: Compare reported postconcussion symptoms for men and women stratified by PTSD diagnostic symptoms (present/absent), mild TBI severity (alteration of consciousness/loss of consciousness), and bodily injury severity (mild/moderate-severe). MAIN MEASURES: Neurobehavioral Symptom Inventory, PTSD Checklist, Abbreviated Injury Scale. RESULTS: Overall postconcussion symptom reporting increased with PTSD but did not significantly differ based on severity of mild TBI or associated bodily injury. Females reported more somatosensory and/or vestibular symptoms than males under some circumstances. Females in the PTSD-Present group, Alteration of Consciousness Only group, and Moderate-Severe Bodily Injury group reported more somatosensory symptoms than males in those groups. Females in the Alteration of Consciousness Only group and Minor Bodily Injury group reported more vestibular symptoms than males in those groups. CONCLUSION: Diagnostically relevant PTSD symptoms, mild TBI severity, and bodily injury severity differentially impact somatosensory and vestibular postconcussion symptom reporting for male and female SM after mild TBI. Controlling for PTSD and symptom validity resulted in fewer gender-based differences in postconcussive symptoms than previously demonstrated in the literature.
Authors: Erin D Bigler; Tracy J Abildskov; Barry Eggleston; Brian A Taylor; David F Tate; Jo Ann Petrie; Mary R Newsome; Randall S Scheibel; Harvey Levin; William C Walker; Naomi Goodrich-Hunsaker; Nicholas J Tustison; James R Stone; Andrew R Mayer; Timothy D Duncan; Gerry E York; Elisabeth A Wilde Journal: Int J Methods Psychiatr Res Date: 2019-05-23 Impact factor: 4.035
Authors: John K Yue; Harvey S Levin; Catherine G Suen; Molly Rose Morrissey; Sarah J Runyon; Ethan A Winkler; Ross C Puffer; Hansen Deng; Caitlin K Robinson; Jonathan W Rick; Ryan R L Phelps; Sourabh Sharma; Sabrina R Taylor; Mary J Vassar; Maryse C Cnossen; Hester F Lingsma; Raquel C Gardner; Nancy R Temkin; Jason Barber; Sureyya S Dikmen; Esther L Yuh; Pratik Mukherjee; Murray B Stein; Tene A Cage; Alex B Valadka; David O Okonkwo; Geoffrey T Manley Journal: Neurol Res Date: 2019-04-21 Impact factor: 2.448
Authors: Eve M Valera; Annie-Lori C Joseph; Katherine Snedaker; Matthew J Breiding; Courtney L Robertson; Angela Colantonio; Harvey Levin; Mary Jo Pugh; Deborah Yurgelun-Todd; Rebekah Mannix; Jeffrey J Bazarian; L Christine Turtzo; Lyn S Turkstra; Lisa Begg; Diana M Cummings; Patrick S F Bellgowan Journal: J Head Trauma Rehabil Date: 2021-01-01 Impact factor: 3.117
Authors: Ali S Farooqi; Starr Jiang; Austin J Borja; Donald K E D Detchou; Ryan Dimentberg; Kaitlyn Shultz; Scott D McClintock; Neil R Malhotra Journal: Cureus Date: 2021-11-29