Literature DB >> 29082756

Blood lead levels, pulmonary function and agility in Polish schoolchildren.

Bert B Little1,2, Zofia Ignasiak3, Teresa Sławinska3, Pawel Posłuszny3, R M Malina1,2,4, David L Wiegman5.   

Abstract

BACKGROUND: Reduced vital capacity (VC) and forced vital capacity (FVC) are associated with lead (Pb) exposure. AIM: The objective of this study is to analyse the effects of Pb on FVC and the shuttle run performance. SUBJECTS AND METHODS: Data were available for 184 male and 189 female Polish schoolchildren aged 10-15 years. Regression analysis was performed of shuttle run performance (dependent) on Pb and FVC.
RESULTS: Shuttle run time increased by 1.75 (± 0.77) and 1.97 (± 0.77) seconds for each 10 µg/dL increase in Pb blood among males and females, respectively. Higher shuttle run times indicate poorer performance. Average unadjusted blood Pb level in the sample was 5.27 μg/dL (± 0.19 SE) and 3.82 μg/dL (± 0.10 SE), respectively. Path analysis was used to assess the association of Pb level with shuttle run time. Blood Pb had a significant negative effect on VC (B= -13.60 ± 3.28 [SE], p < 0.0001) and FVC (B = -13.08 ± 3.27, p < 0.0001). FVC had a small but significant effect on shuttle run time (B = -0.04 ± 0.007, p < 0.0001). Pb had a significant effect on the residual of shuttle run time among males (B = 1.59 ± 0.75, p < 0.03) and females after the effect of FVC was removed (B = 1.49 ± 0.73, p < 0.04).
CONCLUSIONS: Thus, Pb had direct and indirect effects that increased shuttle run time, i.e. negatively affected performance.

Entities:  

Keywords:  Lead (Pb); agility; pulmonary function; schoolchildren

Mesh:

Substances:

Year:  2017        PMID: 29082756     DOI: 10.1080/03014460.2017.1387284

Source DB:  PubMed          Journal:  Ann Hum Biol        ISSN: 0301-4460            Impact factor:   1.533


  4 in total

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Authors:  Nia McRae; Chris Gennings; Nadya Rivera Rivera; Marcela Tamayo-Ortiz; Ivan Pantic; Chitra Amarasiriwardena; Lourdes Schnaas; Rosalind Wright; Martha M Tellez-Rojo; Robert O Wright; Maria José Rosa
Journal:  Environ Res       Date:  2021-11-27       Impact factor: 6.498

2.  Association of heavy metals with measures of pulmonary function in children and youth: Results from the National Health and Nutrition Examination Survey (NHANES).

Authors:  Jessica M Madrigal; Victoria Persky; Andrea Pappalardo; Maria Argos
Journal:  Environ Int       Date:  2018-10-18       Impact factor: 9.621

3.  Prenatal lead exposure and childhood lung function: Influence of maternal cortisol and child sex.

Authors:  Maria José Rosa; Marcela Tamayo-Ortiz; Adriana Mercado Garcia; Nadya Y Rivera Rivera; Douglas Bush; Alison G Lee; Maritsa Solano-González; Chitra Amarasiriwardena; Martha Maria Téllez-Rojo; Robert O Wright; Rosalind J Wright
Journal:  Environ Res       Date:  2021-12-05       Impact factor: 6.498

4.  Toxic metal exposure as a possible risk factor for COVID-19 and other respiratory infectious diseases.

Authors:  Anatoly V Skalny; Thania Rios Rossi Lima; Tao Ke; Ji-Chang Zhou; Julia Bornhorst; Svetlana I Alekseenko; Jan Aaseth; Ourania Anesti; Dimosthenis A Sarigiannis; Aristides Tsatsakis; Michael Aschner; Alexey A Tinkov
Journal:  Food Chem Toxicol       Date:  2020-10-16       Impact factor: 6.023

  4 in total

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