Literature DB >> 29072720

Cannabis through the looking glass: chemo- and enantio-selective separation of phytocannabinoids by enantioselective ultra high performance supercritical fluid chromatography.

G Mazzoccanti1, O H Ismail, I D'Acquarica, C Villani, C Manzo, M Wilcox, A Cavazzini, F Gasparrini.   

Abstract

By using the Inverted Chirality Columns Approach (ICCA) we have developed an enantioselective UHPSFC method to determine the enantiomeric excess (ee) of (-)-Δ9-THC in medicinal marijuana (Bedrocan®). The ee was high (99.73%), but the concentration of the (+)-enantiomer (0.135%) was not negligible, and it is worth a systematic evaluation of bioactivity.

Entities:  

Year:  2017        PMID： 29072720     DOI： 10.1039/c7cc06999e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  9 in total

1.  Using (+)-Carvone to access novel derivatives of (+)-ent-Cannabidiol: the first asymmetric syntheses of (+)-ent-CBDP and (+)-ent-CBDV.

Authors:  Alexandra E Golliher; Antonio J Tenorio; Nina O Dimauro; Nicolas R Mairata; F Omar Holguin; William Maio
Journal:  Tetrahedron Lett       Date:  2021-02-05       Impact factor: 2.415

2.  Cannabis sativa L. Inflorescences from Monoecious Cultivars Grown in Central Italy: An Untargeted Chemical Characterization from Early Flowering to Ripening.

Authors:  Cinzia Ingallina; Anatoly P Sobolev; Simone Circi; Mattia Spano; Caterina Fraschetti; Antonello Filippi; Antonella Di Sotto; Silvia Di Giacomo; Giulia Mazzoccanti; Francesco Gasparrini; Deborah Quaglio; Enio Campiglia; Simone Carradori; Marcello Locatelli; Giuliana Vinci; Mattia Rapa; Salvatore Ciano; Anna Maria Giusti; Bruno Botta; Francesca Ghirga; Donatella Capitani; Luisa Mannina
Journal:  Molecules       Date:  2020-04-20       Impact factor: 4.411

Review 3.  A Nrf-2 Stimulatory Hydroxylated Cannabidiol Derivative from Hemp (Cannabis sativa).

Authors:  Giuseppina Chianese; Carmina Sirignano; Emanuele Benetti; Vittoria Marzaroli; Juan A Collado; Lauren de la Vega; Giovanni Appendino; Eduardo Muñoz; Orazio Taglialatela-Scafati
Journal:  J Nat Prod       Date:  2022-03-22       Impact factor: 4.803

Review 4.  Minor Phytocannabinoids: A Misleading Name but a Promising Opportunity for Biomedical Research.

Authors:  Diego Caprioglio; Hawraz Ibrahim M Amin; Orazio Taglialatela-Scafati; Eduardo Muñoz; Giovanni Appendino
Journal:  Biomolecules       Date:  2022-08-06

Review 5.  Advanced Development of Supercritical Fluid Chromatography in Herbal Medicine Analysis.

Authors:  Min Chen; Shan-Shan Wen; Rui Wang; Qing-Xuan Ren; Chen-Wan Guo; Ping Li; Wen Gao
Journal:  Molecules       Date:  2022-06-29       Impact factor: 4.927

6.  Chirality in Cannabinoid Research.

Authors:  Crist N Filer
Journal:  Cannabis Cannabinoid Res       Date:  2021-02-12

7.  A Multimethodological Characterization of Cannabis sativa L. Inflorescences from Seven Dioecious Cultivars Grown in Italy: The Effect of Different Harvesting Stages.

Authors:  Mattia Spano; Giacomo Di Matteo; Cinzia Ingallina; Bruno Botta; Deborah Quaglio; Francesca Ghirga; Silvia Balducci; Silvia Cammarone; Enio Campiglia; Anna Maria Giusti; Giuliana Vinci; Mattia Rapa; Salvatore Ciano; Luisa Mannina; Anatoly P Sobolev
Journal:  Molecules       Date:  2021-05-14       Impact factor: 4.411

Review 8.  Enantiomeric Mixtures in Natural Product Chemistry: Separation and Absolute Configuration Assignment.

Authors:  Andrea N L Batista; Fernando M Dos Santos; João M Batista; Quezia B Cass
Journal:  Molecules       Date:  2018-02-23       Impact factor: 4.411

9.  The Separation of Cannabinoids on Sub-2 µm Immobilized Polysaccharide Chiral Stationary Phases.

Authors:  Takafumi Onishi; Weston J Umstead
Journal:  Pharmaceuticals (Basel)       Date:  2021-11-30
  9 in total

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