| Literature DB >> 29068706 |
Natalia Becker1, Mailton Vasconcelos2, Vanessa Oliveira2, Fernanda Caroline Dos Santos3, Lisiane Bizarro2, Rosa M M De Almeida2, Jerusa Fumagalli De Salles1, Maria Raquel Santos Carvalho3.
Abstract
Despite advances in the characterization of developmental dyslexia (DD), several questions regarding the interplay between DD-susceptibility genes and environmental risk factors remain open. This systematic review aimed at answering the following questions: What has been the impact of new resources on the knowledge about DD? Which questions remain open? What is the investigative agenda for the short term? Forty-six studies were analyzed. Despite the growing literature on DD candidate genes, most studies have not been replicated. We found large effects on causative genes and smaller environmental contributions, involving maternal smoking during pregnancy, SES and the DYX1C1-1259C/G marker. Implications are discussed.Entities:
Keywords: Developmental dyslexia; environment; genes; molecular genetics; neurobiology; socioeconomic status
Mesh：
Year: 2017 PMID： 29068706 DOI： 10.1080/87565641.2017.1374960
Source DB: PubMed Journal: Dev Neuropsychol ISSN： 1532-6942 Impact factor: 2.253