Literature DB >> 29067505

Length of synostosis and segmented intracranial volume correlate with age in patients with non-syndromic sagittal synostosis.

Arja Heliövaara1, Junnu Leikola2, Virve Koljonen3,4, Pia Vuola2, Mika Koivikko5.   

Abstract

PURPOSE: The aim of this study is to compare the length of synostosis and segmented intracranial volume (SIV) with age in children with non-syndromic sagittal synostosis.
METHODS: Thirty-three consecutive patients (22 boys) who had been operated by cranial vault remodeling because of sagittal synostosis were compared retrospectively from 3D-CT imaging data sets obtained from volumetric CT. The mean age of the patients at preoperative CT imaging was 0.49 (range 0.13-1.3) years and at 1-year postoperative imaging 1.8 (range 1.3-3) years. The mean interval between preoperative CT imaging and surgery was 0.25 (range 0-0.8) years. Pearson's correlation and Student's t test were used in the statistical analyses.
RESULTS: Length of sagittal synostosis correlated positively with age at preoperative CT (r = 0.688, p < 0.01). Children with total synostosis (n = 9) were significantly older (mean age 0.74 vs. 0.4 years, p < 0.01) than those with partial synostosis. Of partial synostoses, 9 were located anteriorly, 3 in the middle, and 12 posteriorly. The mean synostosis ratio (synostosis length/total sagittal suture length × 100) was 83%. Preoperative SIV correlated positively with age at preoperative CT (r = 0.788, p < 0.01), whereas the 1-year postoperative SIV did not correlate with age at operation. The older the child at the time of the operation, the less the percentage SIV increased.
CONCLUSIONS: Length of sagittal synostosis and SIV increased with age.

Entities:  

Keywords:  Craniosynostosis; Intracranial volume; Scaphocephaly; Synostosis length

Mesh:

Year:  2017        PMID: 29067505     DOI: 10.1007/s00381-017-3628-2

Source DB:  PubMed          Journal:  Childs Nerv Syst        ISSN: 0256-7040            Impact factor:   1.475


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