| Literature DB >> 29064133 |
Rossana Rosa1,2, Susan D Rudin3,4, Laura J Rojas3,5, Andrea M Hujer3,4, Armando Perez-Cardona6, Federico Perez3, Robert A Bonomo3,4,5,7,8,9, Octavio Martinez10, Lilian M Abbo2, Jose F Camargo2.
Abstract
Infections with carbapenemase-producing carbapenem-resistant Enterobacteriaceae represent an emergent problem worldwide. Treatment of infections caused by New Delhi metallo-beta-lactamase (NDM)-harboring Enterobacteriaceae is particularly challenging as it frequently involves the use of nephrotoxic agents, which is problematic in kidney transplant recipients and non-renal transplant patients with marginal kidney function. We present two cases of urinary tract infections caused by NDM-harboring Enterobacteriaceae successfully treated with a combination of "double carbapenem" and oral fosfomycin.Entities:
Keywords: NDM; carbapenem-resistant Enterobacteriaceae; carbapenemase; fosfomycin; kidney transplant
Mesh:
Substances:
Year: 2017 PMID: 29064133 PMCID: PMC5809302 DOI: 10.1111/tid.12795
Source DB: PubMed Journal: Transpl Infect Dis ISSN: 1398-2273 Impact factor: 2.228