Literature DB >> 29063555

Representing Knowledge Consistently Across Health Systems.

S T Rosenbloom, R J Carroll, J L Warner, M E Matheny, J C Denny.   

Abstract

Objectives: Electronic health records (EHRs) have increasingly emerged as a powerful source of clinical data that can be leveraged for reuse in research and in modular health apps that integrate into diverse health information technologies. A key challenge to these use cases is representing the knowledge contained within data from different EHR systems in a uniform fashion. Method: We reviewed several recent studies covering the knowledge representation in the common data models for the Observational Medical Outcomes Partnership (OMOP) and its Observational Health Data Sciences and Informatics program, and the United States Patient Centered Outcomes Research Network (PCORNet). We also reviewed the Health Level 7 Fast Healthcare Interoperability Resource standard supporting app-like programs that can be used across multiple EHR and research systems.
Results: There has been a recent growth in high-impact efforts to support quality-assured and standardized clinical data sharing across different institutions and EHR systems. We focused on three major efforts as part of a larger landscape moving towards shareable, transportable, and computable clinical data.
Conclusion: The growth in approaches to developing common data models to support interoperable knowledge representation portends an increasing availability of high-quality clinical data in support of research. Building on these efforts will allow a future whereby significant portions of the populations in the world may be able to share their data for research. Georg Thieme Verlag KG Stuttgart.

Entities:  

Mesh:

Year:  2017        PMID: 29063555      PMCID: PMC6239235          DOI: 10.15265/IY-2017-018

Source DB:  PubMed          Journal:  Yearb Med Inform        ISSN: 0943-4747


  46 in total

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2.  Internal domain-specific language based on Arden Syntax and FHIR.

Authors:  Eizen Kimura; Ken Ishihara
Journal:  Stud Health Technol Inform       Date:  2015

3.  SMART on FHIR Genomics: facilitating standardized clinico-genomic apps.

Authors:  Gil Alterovitz; Jeremy Warner; Peijin Zhang; Yishen Chen; Mollie Ullman-Cullere; David Kreda; Isaac S Kohane
Journal:  J Am Med Inform Assoc       Date:  2015-07-21       Impact factor: 4.497

4.  Accuracy of an automated knowledge base for identifying drug adverse reactions.

Authors:  E A Voss; R D Boyce; P B Ryan; J van der Lei; P R Rijnbeek; M J Schuemie
Journal:  J Biomed Inform       Date:  2016-12-16       Impact factor: 6.317

5.  Bridging the Gap between HL7 CDA and HL7 FHIR: A JSON Based Mapping.

Authors:  Christoph Rinner; Georg Duftschmid
Journal:  Stud Health Technol Inform       Date:  2016

6.  Metadata Repository for Improved Data Sharing and Reuse Based on HL7 FHIR.

Authors:  Hannes Ulrich; Ann-Kristin Kock; Petra Duhm-Harbeck; Jens K Habermann; Josef Ingenerf
Journal:  Stud Health Technol Inform       Date:  2016

7.  Converting ODM Metadata to FHIR Questionnaire Resources.

Authors:  Justin Doods; Philipp Neuhaus; Martin Dugas
Journal:  Stud Health Technol Inform       Date:  2016

8.  Driving Innovation in Health Systems through an Apps-Based Information Economy.

Authors:  Kenneth D Mandl; Joshua C Mandel; Isaac S Kohane
Journal:  Cell Syst       Date:  2015-07       Impact factor: 10.304

9.  Preparing Nursing Home Data from Multiple Sites for Clinical Research - A Case Study Using Observational Health Data Sciences and Informatics.

Authors:  Richard D Boyce; Steven M Handler; Jordan F Karp; Subashan Perera; Charles F Reynolds
Journal:  EGEMS (Wash DC)       Date:  2016-10-26

10.  Launching PCORnet, a national patient-centered clinical research network.

Authors:  Rachael L Fleurence; Lesley H Curtis; Robert M Califf; Richard Platt; Joe V Selby; Jeffrey S Brown
Journal:  J Am Med Inform Assoc       Date:  2014-05-12       Impact factor: 4.497

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  29 in total

1.  HemOnc: A new standard vocabulary for chemotherapy regimen representation in the OMOP common data model.

Authors:  Jeremy L Warner; Dmitry Dymshyts; Christian G Reich; Michael J Gurley; Harry Hochheiser; Zachary H Moldwin; Rimma Belenkaya; Andrew E Williams; Peter C Yang
Journal:  J Biomed Inform       Date:  2019-06-22       Impact factor: 6.317

2.  Clinical Concept Value Sets and Interoperability in Health Data Analytics.

Authors:  Sigfried Gold; Andrea Batch; Robert McClure; Guoqian Jiang; Hadi Kharrazi; Rishi Saripalle; Vojtech Huser; Chunhua Weng; Nancy Roderer; Ana Szarfman; Niklas Elmqvist; David Gotz
Journal:  AMIA Annu Symp Proc       Date:  2018-12-05

3.  Lessons Learned in Creating Interoperable Fast Healthcare Interoperability Resources Profiles for Large-Scale Public Health Programs.

Authors:  Susan A Matney; Bret Heale; Steve Hasley; Emily Decker; Brittni Frederiksen; Nathan Davis; Patrick Langford; Nadia Ramey; Stanley M Huff
Journal:  Appl Clin Inform       Date:  2019-02-06       Impact factor: 2.342

Review 4.  Data integration strategies for predictive analytics in precision medicine.

Authors:  Lewis J Frey
Journal:  Per Med       Date:  2018-11-02       Impact factor: 2.512

5.  ADEpedia-on-OHDSI: A next generation pharmacovigilance signal detection platform using the OHDSI common data model.

Authors:  Yue Yu; Kathryn J Ruddy; Na Hong; Shintaro Tsuji; Andrew Wen; Nilay D Shah; Guoqian Jiang
Journal:  J Biomed Inform       Date:  2019-02-07       Impact factor: 6.317

6.  The Influence of Big (Clinical) Data and Genomics on Precision Medicine and Drug Development.

Authors:  Joshua C Denny; Sara L Van Driest; Wei-Qi Wei; Dan M Roden
Journal:  Clin Pharmacol Ther       Date:  2018-02-05       Impact factor: 6.875

Review 7.  Knowledge Representation and Management, It's Time to Integrate!

Authors:  F Dhombres; J Charlet
Journal:  Yearb Med Inform       Date:  2017-09-11

8.  Improving the phenotype risk score as a scalable approach to identifying patients with Mendelian disease.

Authors:  Lisa Bastarache; Jacob J Hughey; Jeffrey A Goldstein; Julie A Bastraache; Satya Das; Neil Charles Zaki; Chenjie Zeng; Leigh Anne Tang; Dan M Roden; Joshua C Denny
Journal:  J Am Med Inform Assoc       Date:  2019-12-01       Impact factor: 4.497

9.  TRANSLATOR Database-A Vision for a Multi-Institutional Research Network.

Authors:  Manlik Kwong; Heather L Gardner; Neil Dieterle; Virginia Rentko
Journal:  Top Companion Anim Med       Date:  2019-09-11

10.  SMART Cancer Navigator: A Framework for Implementing ASCO Workshop Recommendations to Enable Precision Cancer Medicine.

Authors:  Jeremy L Warner; Ishaan Prasad; Makiah Bennett; Monica Arniella; Alicia Beeghly-Fadiel; Kenneth D Mandl; Gil Alterovitz
Journal:  JCO Precis Oncol       Date:  2018-05-01
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