Literature DB >> 29057338

Single anterior cervical discectomy and fusion (ACDF) using self- locking stand-alone polyetheretherketone (PEEK) cage: evaluation of pain and health-related quality of life.

Stylianos Kapetanakis1, Tryfon Thomaidis1, George Charitoudis1, Pavlos Pavlidis1, Panagiotis Theodosiadis1, Grigorios Gkasdaris1.   

Abstract

BACKGROUND: Anterior cervical discectomy and fusion (ACDF) constitutes the conventional treatment of cervical disc herniation due to degenerative disc disease (DDD). ACDF with plating presents a variety of complications postoperatively and stand-alone cages are thought to be a promising alternative. The aim of this study was firstly, to analyze prospectively collected data from a sample of patients treated with single ACDF using C-Plus self-locking stand-alone PEEK cage system, without the use of plates or screws, in order to evaluate pain levels of patients, utilizing Neck and Arm Pain scale as an expression of visual analogue scale (VAS). Secondly, we aimed to evaluate health-related quality of life, via the short-form 36 (SF-36) and Neck Disability Index (NDI).
METHODS: Thirty-six patients (19 male and 17 female) with mean age 49.6±7 years old who underwent successful single ACDF using self-locking stand-alone PEEK cage for symptomatic cervical DDD were selected for the study. Neck and Arm pain, as well as SF-36 and NDI were estimated preoperatively and 1, 3, 6, and 12 months postoperatively. Patients underwent preoperative and postoperative clinical, neurological and radiological evaluation.
RESULTS: The clinical and radiological outcomes were satisfactory after a minimum 1-year follow-up. All results were statistically important (P<0.05), excluding improvement in NDI measured between 6 and 12 months. SF-36, Neck Pain, as well as Arm Pain featured gradual and constant improvement during follow-up, with best scores presenting at 12 months after surgery, while NDI reached its best at 6 months postoperatively.
CONCLUSIONS: Generally, all scores showed improvement postoperatively during the different phases of the follow-up. Subsequently, ACDF using C-Plus cervical cage constitutes an effective method for cervical disc herniation treatment, in terms of postoperative improvement on pain levels and health-related quality of life and a safe alternative to the conventional method of treatment for cervical DDD.

Entities:  

Keywords:  Anterior cervical discectomy and fusion (ACDF); cervical degenerative disc disease (DDD); pain; quality of life; stand-alone cage

Year:  2017        PMID: 29057338      PMCID: PMC5637207          DOI: 10.21037/jss.2017.06.21

Source DB:  PubMed          Journal:  J Spine Surg        ISSN: 2414-4630


  42 in total

1.  Anterior cervical locking plate-related complications; prevention and treatment recommendations.

Authors:  Xie Ning; Yuan Wen; Ye Xiao-Jian; Ni Bin; Chen De-Yu; Xiao Jian-Ru; Jia Lian-Shun
Journal:  Int Orthop       Date:  2007-05-12       Impact factor: 3.075

Review 2.  Treatment of cervical degenerative disc disease - current status and trends.

Authors:  M C Korinth
Journal:  Zentralbl Neurochir       Date:  2008-07-29

3.  The efficacy of plate construct augmentation versus cage alone in anterior cervical fusion.

Authors:  Kyung-Jin Song; Cyrus E Taghavi; Kwang-Bok Lee; Ji-Hoon Song; Jong-Pil Eun
Journal:  Spine (Phila Pa 1976)       Date:  2009-12-15       Impact factor: 3.468

4.  A comparison of anterior cervical discectomy and fusion (ACDF) using self-locking stand-alone polyetheretherketone (PEEK) cage with ACDF using cage and plate in the treatment of three-level cervical degenerative spondylopathy: a retrospective study with 2-year follow-up.

Authors:  Yuqiao Chen; Guohua Lü; Bing Wang; Lei Li; Lei Kuang
Journal:  Eur Spine J       Date:  2016-02-23       Impact factor: 3.134

5.  A Clinical Comparison of Anterior Cervical Plates Versus Stand-Alone Intervertebral Fusion Devices for Single-Level Anterior Cervical Discectomy and Fusion Procedures.

Authors:  Ripul R Panchal; Kee D Kim; Robert Eastlack; John Lopez; Andrew Clavenna; Daina M Brooks; Gita Joshua
Journal:  World Neurosurg       Date:  2016-12-23       Impact factor: 2.104

6.  A new zero-profile implant for stand-alone anterior cervical interbody fusion.

Authors:  M Scholz; K J Schnake; A Pingel; R Hoffmann; F Kandziora
Journal:  Clin Orthop Relat Res       Date:  2011-03       Impact factor: 4.176

7.  Outcomes of interbody fusion cages used in 1 and 2-levels anterior cervical discectomy and fusion: titanium cages versus polyetheretherketone (PEEK) cages.

Authors:  Chi-Chien Niu; Jen-Chung Liao; Wen-Jer Chen; Lih-Huei Chen
Journal:  J Spinal Disord Tech       Date:  2010-07

Review 8.  Zero-P: a new zero-profile cage-plate device for single and multilevel ACDF. A single institution series with four years maximum follow-up and review of the literature on zero-profile devices.

Authors:  Giuseppe M V Barbagallo; Dario Romano; Francesco Certo; Pietro Milone; Vincenzo Albanese
Journal:  Eur Spine J       Date:  2013-09-24       Impact factor: 3.134

Review 9.  Anterior cervical discectomy and fusion associated complications.

Authors:  Kostas N Fountas; Eftychia Z Kapsalaki; Leonidas G Nikolakakos; Hugh F Smisson; Kim W Johnston; Arthur A Grigorian; Gregory P Lee; Joe S Robinson
Journal:  Spine (Phila Pa 1976)       Date:  2007-10-01       Impact factor: 3.468

10.  Stand-Alone Cages for Anterior Cervical Fusion: Are There No Problems?

Authors:  Sang Youp Han; Hyun Woo Kim; Cheol Young Lee; Hong Rye Kim; Dong Ho Park
Journal:  Korean J Spine       Date:  2016-03-31
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  5 in total

Review 1.  History of Spinal Fusion: Where We Came from and Where We Are Going.

Authors:  Sohrab Virk; Sheeraz Qureshi; Harvinder Sandhu
Journal:  HSS J       Date:  2020-02-25

2.  [Observation of stand-alone MC+polyether-ether-ketone (PEEK) Cage in anterior cervical double-level fusion for more than 2 years follow-up].

Authors:  Bing Jiang; Yuefeng Tao; Haiyun Chen; Xiaodong Huang
Journal:  Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi       Date:  2019-09-15

3.  Preliminary results of anterior cervical arthroplasty by porous alumina ceramic cage for cervical disc herniation surgery.

Authors:  Keyvan Mostofi; Babak Gharaei Moghaddam; Morad Peyravi; Reza Karimi Khouzani
Journal:  J Craniovertebr Junction Spine       Date:  2018 Oct-Dec

4.  A Comparison of 2 Anterior Hybrid Techniques for 3-Level Cervical Degenerative Disc Disease.

Authors:  Han Wang; Yang Meng; Hao Liu; Xiaofei Wang; Chen Ding
Journal:  Med Sci Monit       Date:  2020-11-06

Review 5.  The outcomes of stand alone polyetheretherketone cages in anterior cervical discectomy and fusion.

Authors:  Abdulaziz F Ahmed; Mohammed Al Ateeq Al Dosari; Abdulaziz Al Kuwari; Nasser Mehrab Khan
Journal:  Int Orthop       Date:  2020-08-16       Impact factor: 3.075

  5 in total

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