Literature DB >> 29057311

Targeting RNA binding protein in prostate cancer.

Teng Fei1.   

Abstract

RNA binding protein (RBP) controls multiple aspects of RNA metabolism and plays crucial roles in many physiopathological contexts, including cancer. We recently identified an RBP HNRNPL as a novel prostate cancer dependency via regulation of RNA splicing, suggesting the potential to target RBP or RBP-RNA interaction to treat cancer.

Entities:  

Keywords:  CRISPR screen; HNRNPL; RNA binding protein; RNA splicing; prostate cancer

Year:  2017        PMID： 29057311      PMCID： PMC5644478          DOI： 10.1080/23723556.2017.1353855

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  10 in total

Review 1.  RNA-binding proteins: modular design for efficient function.

Authors:  Bradley M Lunde; Claire Moore; Gabriele Varani
Journal:  Nat Rev Mol Cell Biol       Date:  2007-06       Impact factor: 94.444

2.  Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

Authors:  Teng Fei; Yiwen Chen; Tengfei Xiao; Wei Li; Laura Cato; Peng Zhang; Maura B Cotter; Michaela Bowden; Rosina T Lis; Shuang G Zhao; Qiu Wu; Felix Y Feng; Massimo Loda; Housheng Hansen He; X Shirley Liu; Myles Brown
Journal:  Proc Natl Acad Sci U S A       Date:  2017-06-13       Impact factor: 11.205

Review 3.  RNA-binding proteins in human genetic disease.

Authors:  Kiven E Lukong; Kai-wei Chang; Edouard W Khandjian; Stéphane Richard
Journal:  Trends Genet       Date:  2008-07-01       Impact factor: 11.639

4.  The biogenesis and emerging roles of circular RNAs.

Authors:  Ling-Ling Chen
Journal:  Nat Rev Mol Cell Biol       Date:  2016-02-24       Impact factor: 94.444

Review 5.  hnRNP proteins and the biogenesis of mRNA.

Authors:  G Dreyfuss; M J Matunis; S Piñol-Roma; C G Burd
Journal:  Annu Rev Biochem       Date:  1993       Impact factor: 23.643

Review 6.  The development of androgen-independent prostate cancer.

Authors:  B J Feldman; D Feldman
Journal:  Nat Rev Cancer       Date:  2001-10       Impact factor: 60.716

7.  The long noncoding RNA THRIL regulates TNFα expression through its interaction with hnRNPL.

Authors:  Zhonghan Li; Ti-Chun Chao; Kung-Yen Chang; Nianwei Lin; Veena S Patil; Chisato Shimizu; Steven R Head; Jane C Burns; Tariq M Rana
Journal:  Proc Natl Acad Sci U S A       Date:  2013-12-26       Impact factor: 11.205

8.  HnRNP-L promotes prostate cancer progression by enhancing cell cycling and inhibiting apoptosis.

Authors:  Xumin Zhou; Qi Li; Jincan He; Liren Zhong; Fangpeng Shu; Rongwei Xing; Daojun Lv; Bin Lei; Bo Wan; Yu Yang; Huayan Wu; Xiangming Mao; Yaguang Zou
Journal:  Oncotarget       Date:  2017-03-21

Review 9.  The hnRNP family: insights into their role in health and disease.

Authors:  Thomas Geuens; Delphine Bouhy; Vincent Timmerman
Journal:  Hum Genet       Date:  2016-05-23       Impact factor: 4.132

10.  The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression.

Authors:  Yashar S Niknafs; Sumin Han; Teng Ma; Corey Speers; Chao Zhang; Kari Wilder-Romans; Matthew K Iyer; Sethuramasundaram Pitchiaya; Rohit Malik; Yasuyuki Hosono; John R Prensner; Anton Poliakov; Udit Singhal; Lanbo Xiao; Steven Kregel; Ronald F Siebenaler; Shuang G Zhao; Michael Uhl; Alexander Gawronski; Daniel F Hayes; Lori J Pierce; Xuhong Cao; Colin Collins; Rolf Backofen; Cenk S Sahinalp; James M Rae; Arul M Chinnaiyan; Felix Y Feng
Journal:  Nat Commun       Date:  2016-09-26       Impact factor: 14.919
  10 in total
  1 in total

1.  RNA-binding protein Musashi2 stabilizing androgen receptor drives prostate cancer progression.

Authors:  Jing Zhao; Yu Zhang; Xi-Sheng Liu; Fang-Ming Zhu; Feng Xie; Chen-Yi Jiang; Zi-Ye Zhang; Ying-Li Gao; Yong-Chuan Wang; Bin Li; Shu-Jie Xia; Bang-Min Han
Journal:  Cancer Sci       Date:  2020-01-04       Impact factor: 6.716
  1 in total

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