Literature DB >> 29055035

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Transporters.

Stephen Ph Alexander1, Eamonn Kelly2, Neil V Marrion2, John A Peters3, Elena Faccenda4, Simon D Harding4, Adam J Pawson4, Joanna L Sharman4, Christopher Southan4, Jamie A Davies4.   

Abstract

The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13883/full. Transporters are one of the eight major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2017, and supersedes data presented in the 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature Committee of the Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
© 2017 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of British Pharmacological Society.

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Year:  2017        PMID: 29055035      PMCID: PMC5650669          DOI: 10.1111/bph.13883

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


  1 in total

1.  THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Transporters.

Authors:  Stephen Ph Alexander; Eamonn Kelly; Neil V Marrion; John A Peters; Elena Faccenda; Simon D Harding; Adam J Pawson; Joanna L Sharman; Christopher Southan; Jamie A Davies
Journal:  Br J Pharmacol       Date:  2017-12       Impact factor: 8.739

  1 in total
  174 in total

1.  Efficacy of DPP-4 inhibitors, GLP-1 analogues, and SGLT2 inhibitors as add-ons to metformin monotherapy in T2DM patients: a model-based meta-analysis.

Authors:  Hiroyuki Inoue; Yoko Tamaki; Yushi Kashihara; Shota Muraki; Makoto Kakara; Takeshi Hirota; Ichiro Ieiri
Journal:  Br J Clin Pharmacol       Date:  2018-12-06       Impact factor: 4.335

Review 2.  The role of the gasotransmitter hydrogen sulfide in pathological calcification.

Authors:  Mariela Castelblanco; Sonia Nasi; Andreas Pasch; Alexander So; Nathalie Busso
Journal:  Br J Pharmacol       Date:  2019-07-24       Impact factor: 8.739

3.  Functional interplay between liver X receptor and AMP-activated protein kinase α inhibits atherosclerosis in apolipoprotein E-deficient mice - a new anti-atherogenic strategy.

Authors:  Chuanrui Ma; Wenwen Zhang; Xiaoxiao Yang; Ying Liu; Lipei Liu; Ke Feng; Xiaomeng Zhang; Shu Yang; Lei Sun; Miao Yu; Jie Yang; Xiaoju Li; Wenquan Hu; Robert Q Miao; Yan Zhu; Luyuan Li; Jihong Han; Yuanli Chen; Yajun Duan
Journal:  Br J Pharmacol       Date:  2018-03-23       Impact factor: 8.739

4.  Hippocampal PPARα is a novel therapeutic target for depression and mediates the antidepressant actions of fluoxetine in mice.

Authors:  Lu Song; Hao Wang; Ying-Jie Wang; Jin-Liang Wang; Qing Zhu; Feng Wu; Wei Zhang; Bo Jiang
Journal:  Br J Pharmacol       Date:  2018-06-03       Impact factor: 8.739

5.  Identification and pharmacological profile of SPP1, a potent, functionally selective and brain penetrant agonist at muscarinic M1 receptors.

Authors:  Lisa M Broad; Helen E Sanger; Adrian J Mogg; Ellen M Colvin; Ruud Zwart; David A Evans; Francesca Pasqui; Emanuele Sher; Graham N Wishart; Vanessa N Barth; Christian C Felder; Paul J Goldsmith
Journal:  Br J Pharmacol       Date:  2018-11-16       Impact factor: 8.739

6.  Inhibition of histone deacetylase 7 reverses concentrative nucleoside transporter 2 repression in colorectal cancer by up-regulating histone acetylation state.

Authors:  Chaonan Ye; Kun Han; Jinxiu Lei; Kui Zeng; Su Zeng; Haixing Ju; Lushan Yu
Journal:  Br J Pharmacol       Date:  2018-10-04       Impact factor: 8.739

7.  Catalpol alleviates adriamycin-induced nephropathy by activating the SIRT1 signalling pathway in vivo and in vitro.

Authors:  Jiangnan Zhang; Ran Bi; Qiang Meng; Changyuan Wang; Xiaokui Huo; Zhihao Liu; Chong Wang; Pengyuan Sun; Huijun Sun; Xiaodong Ma; Jingjing Wu; Kexin Liu
Journal:  Br J Pharmacol       Date:  2019-12-11       Impact factor: 8.739

8.  Noradrenaline up-regulates volume-regulated chloride current by PKA-independent cAMP/exchange protein activated by cAMP pathway in human atrial myocytes.

Authors:  Guo-Sheng Xiao; Yan-Hui Zhang; Yan Wang; Hai-Ying Sun; Clive M Baumgarten; Gui-Rong Li
Journal:  Br J Pharmacol       Date:  2018-07-08       Impact factor: 8.739

9.  Glycyrrhizin has a high likelihood to be a victim of drug-drug interactions mediated by hepatic organic anion-transporting polypeptide 1B1/1B3.

Authors:  Jiajia Dong; Olajide E Olaleye; Rongrong Jiang; Jing Li; Chuang Lu; Feifei Du; Fang Xu; Junling Yang; Fengqing Wang; Weiwei Jia; Chuan Li
Journal:  Br J Pharmacol       Date:  2018-07-23       Impact factor: 8.739

10.  Aspirin eugenol ester attenuates oxidative injury of vascular endothelial cells by regulating NOS and Nrf2 signalling pathways.

Authors:  Mei-Zhou Huang; Ya-Jun Yang; Xi-Wang Liu; Zhe Qin; Jian-Yong Li
Journal:  Br J Pharmacol       Date:  2019-03-06       Impact factor: 8.739

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