Literature DB >> 29045374

Perspective: Don't keep it in the family.

Ammar Al-Chalabi1.   

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Year:  2017        PMID: 29045374     DOI: 10.1038/550S112a

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


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  6 in total

1.  Absence of consensus in diagnostic criteria for familial neurodegenerative diseases.

Authors:  Susan Byrne; Marwa Elamin; Peter Bede; Orla Hardiman
Journal:  J Neurol Neurosurg Psychiatry       Date:  2012-04       Impact factor: 10.154

2.  Modelling the effects of penetrance and family size on rates of sporadic and familial disease.

Authors:  Ammar Al-Chalabi; Cathryn M Lewis
Journal:  Hum Hered       Date:  2011-08-12       Impact factor: 0.444

3.  Amyotrophic lateral sclerosis in an urban setting: a population based study of inner city London.

Authors:  Clare A Johnston; Biba R Stanton; Martin R Turner; Rebecca Gray; Ashley Hay-Ming Blunt; David Butt; Mary-Ann Ampong; Christopher E Shaw; P Nigel Leigh; Ammar Al-Chalabi
Journal:  J Neurol       Date:  2006-12       Impact factor: 4.849

4.  The risk to relatives of patients with sporadic amyotrophic lateral sclerosis.

Authors:  Martha F Hanby; Kirsten M Scott; William Scotton; Lokesh Wijesekera; Thomas Mole; Catherine E Ellis; P Nigel Leigh; Christopher E Shaw; Ammar Al-Chalabi
Journal:  Brain       Date:  2011-09-20       Impact factor: 13.501

5.  Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.

Authors:  Wouter van Rheenen; Aleksey Shatunov; Annelot M Dekker; Russell L McLaughlin; Frank P Diekstra; Sara L Pulit; Rick A A van der Spek; Urmo Võsa; Simone de Jong; Matthew R Robinson; Jian Yang; Isabella Fogh; Perry Tc van Doormaal; Gijs H P Tazelaar; Max Koppers; Anna M Blokhuis; William Sproviero; Ashley R Jones; Kevin P Kenna; Kristel R van Eijk; Oliver Harschnitz; Raymond D Schellevis; William J Brands; Jelena Medic; Androniki Menelaou; Alice Vajda; Nicola Ticozzi; Kuang Lin; Boris Rogelj; Katarina Vrabec; Metka Ravnik-Glavač; Blaž Koritnik; Janez Zidar; Lea Leonardis; Leja Dolenc Grošelj; Stéphanie Millecamps; François Salachas; Vincent Meininger; Mamede de Carvalho; Susana Pinto; Jesus S Mora; Ricardo Rojas-García; Meraida Polak; Siddharthan Chandran; Shuna Colville; Robert Swingler; Karen E Morrison; Pamela J Shaw; John Hardy; Richard W Orrell; Alan Pittman; Katie Sidle; Pietro Fratta; Andrea Malaspina; Simon Topp; Susanne Petri; Susanne Abdulla; Carsten Drepper; Michael Sendtner; Thomas Meyer; Roel A Ophoff; Kim A Staats; Martina Wiedau-Pazos; Catherine Lomen-Hoerth; Vivianna M Van Deerlin; John Q Trojanowski; Lauren Elman; Leo McCluskey; A Nazli Basak; Ceren Tunca; Hamid Hamzeiy; Yesim Parman; Thomas Meitinger; Peter Lichtner; Milena Radivojkov-Blagojevic; Christian R Andres; Cindy Maurel; Gilbert Bensimon; Bernhard Landwehrmeyer; Alexis Brice; Christine A M Payan; Safaa Saker-Delye; Alexandra Dürr; Nicholas W Wood; Lukas Tittmann; Wolfgang Lieb; Andre Franke; Marcella Rietschel; Sven Cichon; Markus M Nöthen; Philippe Amouyel; Christophe Tzourio; Jean-François Dartigues; Andre G Uitterlinden; Fernando Rivadeneira; Karol Estrada; Albert Hofman; Charles Curtis; Hylke M Blauw; Anneke J van der Kooi; Marianne de Visser; An Goris; Markus Weber; Christopher E Shaw; Bradley N Smith; Orietta Pansarasa; Cristina Cereda; Roberto Del Bo; Giacomo P Comi; Sandra D'Alfonso; Cinzia Bertolin; Gianni Sorarù; Letizia Mazzini; Viviana Pensato; Cinzia Gellera; Cinzia Tiloca; Antonia Ratti; Andrea Calvo; Cristina Moglia; Maura Brunetti; Simona Arcuti; Rosa Capozzo; Chiara Zecca; Christian Lunetta; Silvana Penco; Nilo Riva; Alessandro Padovani; Massimiliano Filosto; Bernard Muller; Robbert Jan Stuit; Ian Blair; Katharine Zhang; Emily P McCann; Jennifer A Fifita; Garth A Nicholson; Dominic B Rowe; Roger Pamphlett; Matthew C Kiernan; Julian Grosskreutz; Otto W Witte; Thomas Ringer; Tino Prell; Beatrice Stubendorff; Ingo Kurth; Christian A Hübner; P Nigel Leigh; Federico Casale; Adriano Chio; Ettore Beghi; Elisabetta Pupillo; Rosanna Tortelli; Giancarlo Logroscino; John Powell; Albert C Ludolph; Jochen H Weishaupt; Wim Robberecht; Philip Van Damme; Lude Franke; Tune H Pers; Robert H Brown; Jonathan D Glass; John E Landers; Orla Hardiman; Peter M Andersen; Philippe Corcia; Patrick Vourc'h; Vincenzo Silani; Naomi R Wray; Peter M Visscher; Paul I W de Bakker; Michael A van Es; R Jeroen Pasterkamp; Cathryn M Lewis; Gerome Breen; Ammar Al-Chalabi; Leonard H van den Berg; Jan H Veldink
Journal:  Nat Genet       Date:  2016-07-25       Impact factor: 41.307

6.  Analysis of amyotrophic lateral sclerosis as a multistep process: a population-based modelling study.

Authors:  Ammar Al-Chalabi; Andrea Calvo; Adriano Chio; Shuna Colville; Cathy M Ellis; Orla Hardiman; Mark Heverin; Robin S Howard; Mark H B Huisman; Noa Keren; P Nigel Leigh; Letizia Mazzini; Gabriele Mora; Richard W Orrell; James Rooney; Kirsten M Scott; William J Scotton; Meinie Seelen; Christopher E Shaw; Katie S Sidle; Robert Swingler; Miho Tsuda; Jan H Veldink; Anne E Visser; Leonard H van den Berg; Neil Pearce
Journal:  Lancet Neurol       Date:  2014-10-07       Impact factor: 44.182

  6 in total
  7 in total

1.  S-nitrosylated TDP-43 triggers aggregation, cell-to-cell spread, and neurotoxicity in hiPSCs and in vivo models of ALS/FTD.

Authors:  Elaine Pirie; Chang-Ki Oh; Xu Zhang; Xuemei Han; Piotr Cieplak; Henry R Scott; Amanda K Deal; Swagata Ghatak; Fernando J Martinez; Gene W Yeo; John R Yates; Tomohiro Nakamura; Stuart A Lipton
Journal:  Proc Natl Acad Sci U S A       Date:  2021-03-16       Impact factor: 11.205

2.  Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein.

Authors:  Sali M K Farhan; Daniel P Howrigan; Liam E Abbott; Joseph R Klim; Simon D Topp; Andrea E Byrnes; Claire Churchhouse; Hemali Phatnani; Bradley N Smith; Evadnie Rampersaud; Gang Wu; Joanne Wuu; Aleksey Shatunov; Alfredo Iacoangeli; Ahmad Al Khleifat; Daniel A Mordes; Sulagna Ghosh; Kevin Eggan; Rosa Rademakers; Jacob L McCauley; Rebecca Schüle; Stephan Züchner; Michael Benatar; J Paul Taylor; Michael Nalls; Marc Gotkine; Pamela J Shaw; Karen E Morrison; Ammar Al-Chalabi; Bryan Traynor; Christopher E Shaw; David B Goldstein; Matthew B Harms; Mark J Daly; Benjamin M Neale
Journal:  Nat Neurosci       Date:  2019-11-25       Impact factor: 28.771

3.  A Knowledge-Based Machine Learning Approach to Gene Prioritisation in Amyotrophic Lateral Sclerosis.

Authors:  Daniel M Bean; Ammar Al-Chalabi; Richard J B Dobson; Alfredo Iacoangeli
Journal:  Genes (Basel)       Date:  2020-06-19       Impact factor: 4.096

4.  Younger age of onset in familial amyotrophic lateral sclerosis is a result of pathogenic gene variants, rather than ascertainment bias.

Authors:  Puja R Mehta; Ashley R Jones; Sarah Opie-Martin; Aleksey Shatunov; Alfredo Iacoangeli; Ahmad Al Khleifat; Bradley N Smith; Simon Topp; Karen E Morrison; Pamela J Shaw; Christopher E Shaw; Sarah Morgan; Alan Pittman; Ammar Al-Chalabi
Journal:  J Neurol Neurosurg Psychiatry       Date:  2018-09-30       Impact factor: 13.654

5.  Constitutively active SARM1 variants that induce neuropathy are enriched in ALS patients.

Authors:  A Joseph Bloom; Xianrong Mao; Amy Strickland; Yo Sasaki; Jeffrey Milbrandt; Aaron DiAntonio
Journal:  Mol Neurodegener       Date:  2022-01-06       Impact factor: 14.195

6.  The importance of offering early genetic testing in everyone with amyotrophic lateral sclerosis.

Authors:  Kristiana Salmon; Matthew C Kiernan; Seung H Kim; Peter M Andersen; Adriano Chio; Leonard H van den Berg; Philip Van Damme; Ammar Al-Chalabi; Patricia Lillo; Jinsy A Andrews; Angela Genge
Journal:  Brain       Date:  2022-05-24       Impact factor: 15.255

Review 7.  Protein S-nitrosylation and oxidation contribute to protein misfolding in neurodegeneration.

Authors:  Tomohiro Nakamura; Chang-Ki Oh; Xu Zhang; Stuart A Lipton
Journal:  Free Radic Biol Med       Date:  2021-07-02       Impact factor: 8.101

  7 in total

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