MOTIVATION: The size and complexity of modern large-scale genome variation studies demand novel approaches for exploring and sharing the data. In order to unlock the potential of these data for a broad audience of scientists with various areas of expertise, a unified exploration framework is required that is accessible, coherent and user-friendly. RESULTS: Panoptes is an open-source software framework for collaborative visual exploration of large-scale genome variation data and associated metadata in a web browser. It relies on technology choices that allow it to operate in near real-time on very large datasets. It can be used to browse rich, hybrid content in a coherent way, and offers interactive visual analytics approaches to assist the exploration. We illustrate its application using genome variation data of Anopheles gambiae, Plasmodium falciparum and Plasmodium vivax. AVAILABILITY AND IMPLEMENTATION: Freely available at https://github.com/cggh/panoptes, under the GNU Affero General Public License. CONTACT: paul.vauterin@gmail.com.
MOTIVATION: The size and complexity of modern large-scale genome variation studies demand novel approaches for exploring and sharing the data. In order to unlock the potential of these data for a broad audience of scientists with various areas of expertise, a unified exploration framework is required that is accessible, coherent and user-friendly. RESULTS: Panoptes is an open-source software framework for collaborative visual exploration of large-scale genome variation data and associated metadata in a web browser. It relies on technology choices that allow it to operate in near real-time on very large datasets. It can be used to browse rich, hybrid content in a coherent way, and offers interactive visual analytics approaches to assist the exploration. We illustrate its application using genome variation data of Anopheles gambiae, Plasmodium falciparum and Plasmodium vivax. AVAILABILITY AND IMPLEMENTATION: Freely available at https://github.com/cggh/panoptes, under the GNU Affero General Public License. CONTACT: paul.vauterin@gmail.com.
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Authors: Roberto Amato; Sarah Auburn; Richard D Pearson; Olivo Miotto; Jacob Almagro-Garcia; Chanaki Amaratunga; Seila Suon; Sivanna Mao; Rintis Noviyanti; Hidayat Trimarsanto; Jutta Marfurt; Nicholas M Anstey; Timothy William; Maciej F Boni; Christiane Dolecek; Tinh Tran Hien; Nicholas J White; Pascal Michon; Peter Siba; Livingstone Tavul; Gabrielle Harrison; Alyssa Barry; Ivo Mueller; Marcelo U Ferreira; Nadira Karunaweera; Milijaona Randrianarivelojosia; Qi Gao; Christina Hubbart; Lee Hart; Ben Jeffery; Eleanor Drury; Daniel Mead; Mihir Kekre; Susana Campino; Magnus Manske; Victoria J Cornelius; Bronwyn MacInnis; Kirk A Rockett; Alistair Miles; Julian C Rayner; Rick M Fairhurst; Francois Nosten; Ric N Price; Dominic P Kwiatkowski Journal: Nat Genet Date: 2016-06-27 Impact factor: 38.330
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Authors: Tushabe John Vianney; Duncan J Berger; Stephen R Doyle; Geetha Sankaranarayanan; Joel Serubanja; Prossy Kabuubi Nakawungu; Fred Besigye; Richard E Sanya; Nancy Holroyd; Fiona Allan; Emily L Webb; Alison M Elliott; Matthew Berriman; James A Cotton Journal: PLoS Negl Trop Dis Date: 2022-08-18