Fatma Ülger1, Mehtap Pehlivanlar Küçük1, Çağatay Erman Öztürk1, İskender Aksoy2, Ahmet Oğuzhan Küçük3, Naci Murat4. 1. a Department of Anesthesiology and Reanimation, Division Of Intensive Care Medicine, Faculty Of Medicine , Ondokuz Mayıs University , Samsun , 55100 , Turkey. 2. b Department of Emergency Medicine, Faculty Of Medicine , Ondokuz Mayıs University , Samsun , 55100 , Turkey. 3. c Department of Anesthesiology and Reanimation , Gazi State Hospital , Samsun , 55080 , Turkey. 4. d Department of Industrial Engineering, Faculty of Engineering , Ondokuz Mayıs University , Samsun , 55100 , Turkey.
Abstract
OBJECTIVE: The aim of the present study is to evaluate the frequency, etiology, risk factors and clinical outcomes in acute traumatic SCI patients who develop fever and to evaluate the relationship between fever and mortality. DESIGN: Retrospective data were collected between January 2007 and August 2016 from patients diagnosed with persistent fever from SCI cases observed in the ICU. PARTICIPANTS: Among 5370 intensive care patients, 435 SCI patients were evaluated for the presence of fever. A total of 52 patients meeting the criteria were evaluated. OUTCOME MEASURES: Fever characteristics were evaluated by dividing the patients into two groups: infectious (group-1) and non-infectious (group-2) fever. Demographic and clinical data, ICU and hospital stay, and mortality were evaluated. RESULTS: In the patients with noninfectious fever, mortality was significantly higher compared to the group with infectious fever (P < 0.001). Of 52 acute SCI cases, 25 (48.1%) had neurogenic fever that did not respond to treatment in intensive care follow-up, and 22 (88%) of these patients died. Maximal fever was 39.10 ± 0.64 °C in Group-1 and 40.22 ± 1.10 ° C in Group-2 (P = 0.001). There was a significant difference in the duration of ICU stay and hospital stay between the two groups (P = 0.005, P = 0.001, respectively), while there was no difference in the duration of mechanical ventilation between the groups (P = 0.544). CONCLUSION: This study demonstrates that patients diagnosed with neurogenic fever following SCI had higher average body temperature and higher rates of mortality compared to patients diagnosed with infectious fever.
OBJECTIVE: The aim of the present study is to evaluate the frequency, etiology, risk factors and clinical outcomes in acute traumatic SCIpatients who develop fever and to evaluate the relationship between fever and mortality. DESIGN: Retrospective data were collected between January 2007 and August 2016 from patients diagnosed with persistent fever from SCI cases observed in the ICU. PARTICIPANTS: Among 5370 intensive care patients, 435 SCI patients were evaluated for the presence of fever. A total of 52 patients meeting the criteria were evaluated. OUTCOME MEASURES: Fever characteristics were evaluated by dividing the patients into two groups: infectious (group-1) and non-infectious (group-2) fever. Demographic and clinical data, ICU and hospital stay, and mortality were evaluated. RESULTS: In the patients with noninfectious fever, mortality was significantly higher compared to the group with infectious fever (P < 0.001). Of 52 acute SCI cases, 25 (48.1%) had neurogenic fever that did not respond to treatment in intensive care follow-up, and 22 (88%) of these patients died. Maximal fever was 39.10 ± 0.64 °C in Group-1 and 40.22 ± 1.10 ° C in Group-2 (P = 0.001). There was a significant difference in the duration of ICU stay and hospital stay between the two groups (P = 0.005, P = 0.001, respectively), while there was no difference in the duration of mechanical ventilation between the groups (P = 0.544). CONCLUSION: This study demonstrates that patients diagnosed with neurogenic fever following SCI had higher average body temperature and higher rates of mortality compared to patients diagnosed with infectious fever.
Authors: Ralph J Marino; Tarcisio Barros; Fin Biering-Sorensen; Stephen P Burns; William H Donovan; Daniel E Graves; Michael Haak; Lesley M Hudson; Michael M Priebe Journal: J Spinal Cord Med Date: 2003 Impact factor: 1.985
Authors: A Fernandez; J M Schmidt; J Claassen; M Pavlicova; D Huddleston; K T Kreiter; N D Ostapkovich; R G Kowalski; A Parra; E Sander Connolly; S A Mayer Journal: Neurology Date: 2007-02-21 Impact factor: 9.910