Literature DB >> 29023540

Emotional and tangible social support in a German population-based sample: Development and validation of the Brief Social Support Scale (BS6).

Manfred E Beutel1, Elmar Brähler1, Jörg Wiltink1, Matthias Michal1, Eva M Klein1, Claus Jünger2, Philipp S Wild3,4,5, Thomas Münzel3, Maria Blettner6, Karl Lackner7, Stefan Nickels8, Ana N Tibubos1.   

Abstract

Aim of the study was the development and validation of the psychometric properties of a six-item bi-factorial instrument for the assessment of social support (emotional and tangible support) with a population-based sample. A cross-sectional data set of N = 15,010 participants enrolled in the Gutenberg Health Study (GHS) in 2007-2012 was divided in two sub-samples. The GHS is a population-based, prospective, observational single-center cohort study in the Rhein-Main-Region in western Mid-Germany. The first sub-sample was used for scale development by performing an exploratory factor analysis. In order to test construct validity, confirmatory factor analyses were run to compare the extracted bi-factorial model with the one-factor solution. Reliability of the scales was indicated by calculating internal consistency. External validity was tested by investigating demographic characteristics health behavior, and distress using analysis of variance, Spearman and Pearson correlation analysis, and logistic regression analysis. Based on an exploratory factor analysis, a set of six items was extracted representing two independent factors. The two-factor structure of the Brief Social Support Scale (BS6) was confirmed by the results of the confirmatory factor analyses. Fit indices of the bi-factorial model were good and better compared to the one-factor solution. External validity was demonstrated for the BS6. The BS6 is a reliable and valid short scale that can be applied in social surveys due to its brevity to assess emotional and practical dimensions of social support.

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Year:  2017        PMID: 29023540      PMCID: PMC5638535          DOI: 10.1371/journal.pone.0186516

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


Introduction

The presence of social relationships has been associated with a great number of mental and physical health outcomes. Social ties have a beneficial influence on the maintenance of psychological well-being and health-promoting behavior [1]. Structural features of social integration comprise of characteristics such as marital status, living alone or the size of a person’s social network. Functional parameters usually refer to the perceived, respectively anticipated support from the social environment [2, 3]. Loneliness refers to a discrepancy between desired and available social relationships [4], a perceived sense of isolation [5], separateness or exclusion [6]. Following the seminal work of House et al. [7], a recent meta-analysis of 148 studies (totaling up to over 308.000 participants) found a 50% increased likelihood of survival in participants with stronger social ties taking into account initial health status, cause of death, and duration of follow-up. This was true for social integration and for social support, respectively its lack in loneliness [8]. Another meta-analysis [9] found that low social participation, less frequent social contact and more loneliness, but not size of the social network were statistically associated with incident dementia with similar rates of likelihood. There are two models explaining the association of social relationships to health outcomes. The main effects model proposes beneficial cognitive, emotional, behavioral and biological influences of social relationships, such as providing stimulation and activity, stimulating brain activity, modeling health behavior, or promoting self-esteem or purpose in life by providing meaningful social roles. The buffering hypothesis proposes that social relationships provide emotional, informational or tangible resources that promote adaptation in case of stress or adversity [10, 11]. Many scales have been proposed to assess social support in the last decades, e.g. Duke-UNC Functional Social Support Questionnaire [12], Oslo Social Support Scale [13], Sarason’s Social Support Questionnaire [14], Interpersonal Support Evaluation List [15]. One established scale for measuring social support is the MOS (Medical Outcomes Study) Social Support Survey, which was developed based on responses of 2,987 chronically ill adults [16]. Of the 19 original items, one was dropped as it belonged to two scales. 18 items assess four dimensions of support: emotional-informational (emotional support and guidance or advice), tangible support (i.e. material aid or assistance), affectionate support (expressing love and affection), and positive social interaction (provided by individuals with whom it is fun to do things). A number of subsequent studies have also been mostly done on medically ill patients, e.g. American breast cancer patients [17] or Spanish outpatients from a primary care center [18]. Given its easy comprehensibility with a single sentence stem “If you needed it, how often is someone available…”, the instrument lends itself to use in a wide range of populations and age groups. Except for the Australian study of Holden et al. [19], population-based studies, however, have been scarce. One reason limiting its use may be the length of the scale. So far, a number of different scales have been developed, based on the initial item pool of the MOS trial with a range from 4 [20], 6 [19], 8 [17] and 12-item scales [20]. The numbers of factors also varies from 1 [18], 2 [17] to 4 [20]. Yet, even those papers endorsing more than one dimension usually used the total score of the respective scale for validation (e.g. [17, 19]), and no evidence has been presented for differential significance of the respective subscales. Social support has been found to improve mental health and health-promoting behavior [1]. Most analyses identified the two dimensions of emotional-informational and tangible support [19-21]. There is some evidence that the distinction of both facets, emotional-informational and tangible support, are crucial [1, 22, 23], as affective support and material assistance can be provided by different environmental resources. Emotional-informational support mainly covers psychological components, particularly emotional and cognitive needs. Tangible support on the other hand, is based on practical support, such as material aid and behavioral assistance [16]. So far, an instrument accounting for the need of factorial differentiation of these two facets of social support is lacking. Especially the development of a bi-factorial questionnaire which can be used in population-based studies to collect representative data seems reasonable. For this reason, the aim of this paper was to develop and validate a Brief Social Support Scale (BS6) based on the MOS Social Support Survey that reliably assesses emotional-informational as well as tangible support. The database was provided by the Gutenberg Health Study (GHS) which is a German population-based, prospective, observational single-center cohort study. To the best of our knowledge, this study is the first validating items of the MOS Social Support Survey including country specific data based on representative data collection. A factor-analytical approach was chosen to extract a bi-factorial brief version of the MOS Social Support Survey. In order to indicate external validity of the scales, socio-demographic data and health-related variables were analyzed which have been associated with facets of social-support [17, 24]. The following hypotheses were tested: There are two underlying independent factors representing aspects of social support, namely emotional-informational support and tangible support. Emotional-informational support and tangible support are associated with distress (depression, generalized anxiety, social phobia, panic disorder, suicidal ideation), physical and mental well-being, and health behavior (smoking, BMI, physical activity, alcohol consumption).

Methods

Study sample

We investigated cross-sectional data of N = 15,010 participants enrolled in GHS from April 2007 to April 2012 [25]. The GHS is a population-based, prospective, observational single-center cohort study in the Rhein-Main-Region in western Mid-Germany. The study protocol and study documents were approved by the local ethics committee of the Medical Chamber of Rhineland-Palatinate, Germany (reference no. 837.020.07; original vote: 22.3.2007, latest update: 20.10.2015). The primary aim of the study is to evaluate and improve cardiovascular risk stratification. The sample was drawn randomly from the local registry in the city of Mainz and the district of Mainz-Bingen. A multi-method approach was used for recruitment (see also [25]). For this purpose, an algorithm was developed defining time frames for establishing contact with the study participants. Overall, participants were contacted up to three times by postal means and up to 20 times by telephone. Participants who did not participate in the GHS study were asked to take part in a structured interview in order to gain information for non-responder analyses with regard to selection bias. The sample was stratified 1:1 for sex and residence and in equal strata for decades of age. Inclusion criteria were age 35 to 74 years and written informed consent. Persons with insufficient knowledge of German language, or physical and mental inability to participate were excluded. Based on the interim analysis 5.8% were excluded because of the exclusion criteria. The response rate (defined as the recruitment efficacy proportion, i.e. the number of persons with participation in or appointment for the baseline examination divided by the sum of number of persons with participation in or appointment for the baseline examination plus those with refusal and those who were not contactable) was 60.3%. Sociodemographic details of the sample are displayed in S1 Table.

Materials and assessment

The 5-hour baseline-examination in the study center comprised evaluation of prevalent classical cardiovascular risk factors and clinical variables, a computer-assisted personal interview, laboratory examinations from a venous blood sample, blood pressure and anthropometric measurements. In general, all examinations were performed according to standard operating procedures by certified medical technical assistants.

Questionnaires

The MOS Social Support Survey with 20 items was devised to assess social support based on the four dimensions of emotional-informational, tangible, affectionate support und positive social interaction. Based on samples of patients with medical diseases, Moser et al. [17] devised a brief scale with 8 items and two subscales (emotional and instrumental support, 4 items, each). GHS participants filled in part of the MOS assessing emotional-informational and tangible support (9 items). Items are rated from 1 = never, 2 = occasionally, 3 = mostly to 4 = always available. An additional item was assessed to estimate the number of persons the participants can count on in cases of emergency (no one to 3 and more). Depression was measured by the Patient Health Questionnaire (PHQ-9), which quantifies the frequency of being bothered by each of the 9 diagnostic criteria of Major Depression over the past 2 weeks. Responses are summed to create a score between 0 and 27 points. A PHQ-9 sum score of ≥ 10 was used for the definition of caseness for depression yielding a sensitivity of 81% and a specificity of 82% for any depressive disorder [26]. Generalized anxiety was assessed with the two screening items of the short form of the GAD-7 (Generalized Anxiety Disorder [GAD]-7 Scale [27]). “Feeling nervous, anxious or on edge” and “Not being able to stop or control worrying”. Subjects can answer these items with 0 = “not at all”, 1 = “several days”, 2 = “over half the days”, and 3 = “nearly every day”. A sum score of 3 and more (range 0–6) out of these two items indicates generalized anxiety with good sensitivity (86%) and specificity (83%). Both the GAD-7 and its two core items (GAD-2) have been shown to perform well as a screening tool for all anxiety disorders [28].

Computer-assisted personal interview

During the computer-assisted personal interview participants were asked whether they had ever received the definite diagnosis of any depressive disorder (medical history of lifetime diagnosis of any depressive disorder, MH of Depression) by a physician. The socioeconomic status (SES) was defined according to Lampert’s and Kroll’s scores of SES with a range from 3 to 27 (3 indicates the lowest SES and 27 the highest SES) [29].

Statistical analysis

For the scale development, a factor-analytical approach was used. Item selection was based on exploratory factor analysis. Subsequently, a confirmatory factor analysis for testing the postulated bi-factorial model was conducted. Descriptive analyses, correlation and regression analyses were performed to validate the subscales with external criteria. Variables were reported as absolute numbers, percentage or mean with standard deviation or medians with 25th and 75th percentiles as appropriate. For comparison of groups Cochran-Armitage Test or Jonckheere-Terpstra Test were performed. All reported p-values correspond to 2-tailed tests. As this part of the study is explorative, no adjustments for multiple testing have been done. P-values are given for descriptive reasons only. Due to the large number of tests, p-values should be interpreted with caution and in connection with effect estimates. Statistical analyses were performed using SAS for Windows 9.4 TS Level 1M1 (SAS Institute Inc.) Cary, NC, USA. For factor analyses, the software R 3.2.3 (package lavaan 0.5–22) was used.

Results

Factor analyses: Exploratory factor analysis and confirmatory factor analysis

Two sets of factor analyses were conducted after splitting the sample in two subsamples by randomization: An exploratory factor analysis with varimax rotation (n = 7,256) and a confirmatory factor analysis (n = 7,255). Table 1 and Fig 1 present the findings from the exploratory factor analysis with varimax rotation. As we were interested in developing a brief scale, we deleted three items with overlapping factor loadings (“to do something enjoyable with 38/.44“, “to have a good time with .56/.46”, “whose advice you really want .65/.39”). Based on 6 items (see Table 1), we identified two independent factors (r = .07) by means of exploratory factor analysis and referring to the scree-test (see Fig 1). Factor 1 explained 35% and factor 2 explained 34% of the variance. The first factor comprises items representing emotional-informational support, the second factor tangible support.
Table 1

Item statistics including mean score, standard deviation, factor loadings, and corrected item-total-correlation.

EnglishGermanMean (±SD)Factor loadingsritrit
Factor 1*(emotional-informational support)Factor 2*(tangible support)Factor 1*Factor 2*
If you needed it, how often is someone available…Wie häufig steht Ihnen folgende Unterstützung durch andereMenschen zur Verfügung?
Tangible support
To take you to the doctor if you need itJemand, der Sie zum Arzt fährt, wenn es nötig ist3.5 (±0.8)0.640.300.61
To prepare your meals if you are unable to do it yourselfJemand, der Ihnen Essen zubereitet, wenn Sie dazu nicht in der Lage sind3.5(±0.8)0.900.270.78
To help with daily chores if you were sickJemand, der Ihnen bei alltäglichen Arbeiten hilft, wenn Sie krank sind3.4(±0.8)0.800.300.75
Emotional-informational support
To give you good advice about a crisisJemand, der Ihnen inschwierigen Situationen guteRatschläge gibt3.4(±0.8)0.690.640.33
To confide in or talk to about yourself or your problemsJemand, dem Sie sichanvertrauen oder mit dem Sie über persönliche Probleme sprechen können3.4(±0.8)0.870.770.28
Who understands your problemsJemand, der Ihre Problemeversteht3.3(±0.8)0.820.760.28

* Calculated by exploratory factor analysis.

Fig 1

Factor extraction based on exploratory factor analysis.

* Calculated by exploratory factor analysis. Reliability of the subscales indicated by Cronbach´s alpha was satisfactory: emotional-informational support α = .87, tangible support α = .86, overall α = .86. Model fit was evaluated by using following model fit indices: Chi-square statistic; the comparative-fit-index (CFI) and the Tucker-Lewis Index (TLI) to describe incremental fit; the root mean square error of approximation (RMSEA) was used as an absolute measure of fit. Values of TLI and CFI close to .95 or higher indicate a better fit. RMSEA should be 0.08 or smaller [30]. Confirmatory factor analyses yielded a good fit for the bi-factor-model (see Fig 2): RMSEA .030 (90% CI .023-.038), CFI = .996, TLI = .993, and SRMR = .029. In contrast, the one-factor-model reached an unacceptable fit: RMSEA .127 (90% CI .121-.134), CFI = .929, TLI = .882, and SRMR = .125.
Fig 2

Factor structure of the Brief Social Support Scale (BS6).

Note: Confirmatory factor analysis with completely standardized solution.

Factor structure of the Brief Social Support Scale (BS6).

Note: Confirmatory factor analysis with completely standardized solution.

Association of social support and its subscales with demographic characteristics health behavior, and distress

Table 2 gives an overview according to different degrees of social support. Sum scores of social support were stratified by quartiles into low (6–11), moderate (at least occasional support), high (at least mostly supported) to very high (maximum count, always supported).
Table 2

Social support and its associations with demographic characteristics, health behavior, and distress.

Social support descriptive statisticsCorrelation coefficientsPearson/ Spearman
low6–11N = 444(3.0%)moderate12–17N = 2213 (15.2%)high18–23N = 8032 (55.2%)very high24N = 3873 (26.6%)p-valueSocial supportEmotional-informational supportTangible support
Age (in years, M, SD)56.9 (11.1)55.1 (10.9)54.4 (11.0)55.6 (11.3).15-0.010.01/ 0.04-0.03/ -0.03
Women (%)53.654.148.848.1< .0001-0.04-0.18/ -0.190.10/ 0.12
Partnership (%)43.165.383.789.9< .00010.280.35/ 0.300.06/ 0.04
Children (%)76.680.685.485.7< .00010.080.07/ 0.060.03/ 0.03
Socioeconomic status10.212.113.113.5< .00010.160.12/ 0.090.10/ 0.09
Employment45.557.964.058.4< .050.030.03/ 0.010.02/ 0.01
Migrant35.228.922.419.8< .0001-0.09-0.06/ -0.04-0.06/ -0.06
Smoker (%)29.824.519.714.5< .0001-0.10-0.06/ -0.06-0.08/ -0.08
Obesity (BMI ≥ 30 kg/m2, %)29.526.524.824.1< .01-0.020.02/ 0.06-0.05/ -0.06
Alcohol (in gram/day, M, SD)9.7 (20.5)10.5 (17.1)11.2 (16.5)11.7 (17.0)< .00010.030.06/ 0.07-0.02/ -0.00
Hyperlipidemia (%)41.937.034.435.0< .0001-0.030.03/ 0.04-0.06/ -0.05
Diabetes 1) (%)14.010.78.68.3< .0001-0.05-0.02/ -0.00-0.05/ -0.04
CVD 2) (%)15.812.09.69.9< .0001-0.03-0.00/ 0.01-0.05/ -0.04
Depression (PHQ-9 ≥ 10, %)24.518.36.32.8< .0001-0.32 4)-0.22/ -0.17-0.25/ -0.22
Suicidal ideation (%)25.716.56.33.4< .0001-0.20-0.13/ -0.10-0.17/ -0.14
Generalized anxiety (GAD ≥ 3, %)19.113.45.92.9< .0001-0.22 4)-0.16/ -0.14-0.17/ -0.14
Panic attack (past 4 weeks)12.610.25.13.5< .0001-0.11-0.09/ -0.07-0.08/ -0.06
Social Phobia (Mini-Spin ≥ 6)10.88.13.21.8< .0001-0.12-0.08/ -0.06-0.11/ -0.09
CDS-2 ≥ 3 (Depersonalisation)5.91.90.50.2< .0001-0.11-0.07/ -0.05-0.08/ -0.06
Sleep disorder 3) (%)37.030.618.913.1< .0001-0.16-0.12/ -0.09-0.13/ -0.11
Type D Helmholtz45.038.523.014.6< .0001-0.21-0.11/ -0.09-0.19/ -0.17
Analgetics13.310.79.28.2< .0001-0.03-0.03/ -0.03-0.02/ -0.02
Opioids3.61.81.31.2< .0001-0.03-0.02/ -0.02-0.03/ -0.03
Antidepressants12.510.24.83.6< .0001-0.11-0.10/ -0.08-0.06/ -0.05
Physician visit last month50.548.042.240.7< .0001-0.05-0.05/ -0.04-0.03/ -0.02
Overall health (M, SD)6.4 (1.9)6.7 (1.8)7.3 (1.6)7.7 (1.5)< .00010.220.12/ 0.080.19/ 0.18

Note: Cochran-Armitage Test or Jonckheere-Terpstra Test were performed for group comparisons.

1) based on medication, HbA1c, medical diagnosis

2) CVD: Myocardial Infarction, CHD, Stroke, Peripheral Arterial Disease

3) at least half the days/ everyday

4) based on scale sum score

Note: Cochran-Armitage Test or Jonckheere-Terpstra Test were performed for group comparisons. 1) based on medication, HbA1c, medical diagnosis 2) CVD: Myocardial Infarction, CHD, Stroke, Peripheral Arterial Disease 3) at least half the days/ everyday 4) based on scale sum score The majority reported high (55%), followed by very high (27%) support. Fifteen percent reported moderate and only 3% low support. Age did not play a role, however, women reported lower support than men. Participants with low support were at a clear social disadvantage regarding partnership, children, socioeconomic status, lack of employment, and a migration background. They had by far the highest rates of cardiovascular risk (smoking, obesity, hyperlipidemia), physical disease (cardiovascular, diabetes). They had the highest rates of distress (depression, suicidal ideation, GAD, panic attacks, social phobia, depersonalization, sleep disorder, Type D personality) and the highest intake of analgetics, opioids and antidepressants and most frequently visited physicians.

Emotional-informational and tangible support as a predictor of mental disease

In multivariate analyses we predicted distress by the two subscales of social support. Even when we adjusted for age, sex, CVD, CVD risk, SES and number of persons in the household, both emotional-informational and tangible support were highly predictive of lower depression, suicidality, generalized anxiety, panic, social phobia, depersonalization, sleep disorder. For social anxiety and Type D personality, emotional support seems to be more important than practical support. When controlling for age, sex, CVD, CVD risk, SES, and number of persons in the household, for all listed mental problems, except for depersonalization, emotional-informational support appears to be a better predictor than tangible support. Overall, higher age and social status were associated with lower distress, whereas female sex and the presence of CVD were associated with higher distress. The results are displayed in Table 3.
Table 3

Independent predictors for distress symptoms in logistic regression models.

DistressOdds Ratio*95%-CIOdds Ratio95%-CI
Depression
    Emotional-informational0.66(0.62–0.70)0.71(0.67–0.76)
    Tangible0.58(0.54–0.61)0.57(0.54–0.61)
General anxiety
    Emotional-informational 0.70(0.66–0.74)0.75(0.70–0.80)
    Tangible0.66(0.62–0.700.63(0.59–0.67)
Suicidality
    Emotional-informational 0.70(0.66–0.74)0.77(0.73–0.82)
    Tangible0.59(0.55–0.62)0.59(0.56–0.63)
Panic
    Emotional-informational 0.74(0.69–0.79)0.79(0.73–0.85)
    Tangible0.76(0.71–0.81)0.75(0.69–0.80)
Social anxiety
    Emotional-informational 0.75(0.70–0.81)0.81(0.75–0.89)
    Tangible0.63(0.58–0.68)0.60(0.56–0.66)
Sleep disorder
    Emotional-informational 0.77(0.74–0.80)0.82(0.79–0.86)
    Tangible0.74(0.71–0.77)0.73(0.70–0.77)
Depersonalization
    Emotional-informational 0.61(0.52–0.70)0.64(0.53–0.76)
    Tangible0.52(0.44–0.61)0.49(0.41–0.59)
Type D Personality
    Emotional-informational 0.79(0.76–0.83)0.81(0.78–0.85)
    Tangible0.65(0.63–0.68)0.65(0.62–0.68)

* univariate analysis

† Adjusted for the following variables: age, sex, cardiovascular disease, cardiovascular risk factor, socioeconomic status, one-person household

‡ Calculated by explorative factor analysis

Abbreviations: CI = Confidence interval

* univariate analysis † Adjusted for the following variables: age, sex, cardiovascular disease, cardiovascular risk factor, socioeconomic status, one-person household ‡ Calculated by explorative factor analysis Abbreviations: CI = Confidence interval

Discussion

The postulated hypotheses were borne out by analyzing two independent population-based subsamples. First, we successfully derived a brief scale with only six items (see S2 Table). We could reproduce the factor structure of previous brief scales with two independent dimensions, emotional-informational support and tangible support assessed by three items each. Second, confirmatory factor analysis showed a very good fit for the bi-factorial model in comparison to the one-factor solution renderings support for the need of differentiation of both facets of social support. As summarized by [21], most of the studies using the MOS Social Support Survey show different factor structures depending on the chosen factor analytical approach. However, our findings based on a German population-based sample clearly indicate a two-factor structure regardless of the used methodological approach. Different associations of some socio-demographic and health-related variables with emotional-informational and tangible support were observed, corroborating the assumption of differentiating effects of both facets of social support. People in a partnership are more likely to experience emotional-information support, whereas the experience of tangible support seems not to be correlated with having a partner. Type D personality and overall health seem to have a slightly stronger association with practical support. From a psychological perspective, the knowledge about the divergence of emotional and practical pathways might be crucial to provide adequate support. The relevance of emotional and practical support probably differs depending on situational variables and interindividual differences. Nevertheless, similar to previous studies low social support was found generally in socially disadvantaged participants [31, 32]. Emotional-informational and tangible support were in sum consistently predictive of a better mental health, even when adjusting of determinants of distress such as female sex, low SES, and the presence of CVD. For social anxiety and Type D personality, emotional-informational support seems to be crucial. When adjusting for age, sex, CVD, CVD risk, SES, and number of persons in the household, emotional support appears to be more important to predict mental health. The results emphasize the practical implication of distinguishing between the emotional and practical dimension of social support. However, one limitation of the study is the age range of the sample beginning with 35 years. Due to the lack of adolescents and adults in their twenties or early thirties in our sample, the full range of age related aspects with regard to dimensions of social support have not been investigated in this study. Especially the impact of perceived social support on personality development and health in critical stages of life while reaching adulthood needs further research with sound study designs. Taking into consideration the strict time constraints to which large scale data collection are subject, extensive assessment tools are usually not applicable for these kind of survey research. The efficiency of this brief scale was demonstrated by presenting validation testing with a number of health related variables. Findings with external criteria were in line with results of other MOS Social Support Surveys (e.g. [16, 17, 19]). The generalizability of the study results is high because of the underlying population-based sample. With the BS6, we provide a reliable and valid short scale that can be applied in social surveys due to its brevity to assess emotional and practical dimensions of social support.

Sample characteristics based on sociodemographic variables.

(DOCX) Click here for additional data file.

Brief Social Support Scale (BS6).

(DOCX) Click here for additional data file.
  23 in total

1.  The MOS social support survey.

Authors:  C D Sherbourne; A L Stewart
Journal:  Soc Sci Med       Date:  1991       Impact factor: 4.634

2.  A Short Scale for Measuring Loneliness in Large Surveys: Results From Two Population-Based Studies.

Authors:  Mary Elizabeth Hughes; Linda J Waite; Louise C Hawkley; John T Cacioppo
Journal:  Res Aging       Date:  2004

3.  A brief form of the Perceived Social Support Questionnaire (F-SozU) was developed, validated, and standardized.

Authors:  Sören Kliem; Thomas Mößle; Florian Rehbein; Deborah F Hellmann; Markus Zenger; Elmar Brähler
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4.  Psychometric properties of the eight-item modified Medical Outcomes Study Social Support Survey based on Spanish outpatients.

Authors:  Paloma Gómez-Campelo; Elisa M Pérez-Moreno; Carmen de Burgos-Lunar; Carmen Bragado-Álvarez; Rodrigo Jiménez-García; Miguel Á Salinero-Fort
Journal:  Qual Life Res       Date:  2014-02-23       Impact factor: 4.147

Review 5.  Stress, social support, and the buffering hypothesis.

Authors:  S Cohen; T A Wills
Journal:  Psychol Bull       Date:  1985-09       Impact factor: 17.737

Review 6.  Social ties and mental health.

Authors:  I Kawachi; L F Berkman
Journal:  J Urban Health       Date:  2001-09       Impact factor: 3.671

7.  Validation and standardization of the Generalized Anxiety Disorder Screener (GAD-7) in the general population.

Authors:  Bernd Löwe; Oliver Decker; Stefanie Müller; Elmar Brähler; Dieter Schellberg; Wolfgang Herzog; Philipp Yorck Herzberg
Journal:  Med Care       Date:  2008-03       Impact factor: 2.983

8.  Validation of the MOS Social Support Survey 6-item (MOS-SSS-6) measure with two large population-based samples of Australian women.

Authors:  Libby Holden; Christina Lee; Richard Hockey; Robert S Ware; Annette J Dobson
Journal:  Qual Life Res       Date:  2014-06-25       Impact factor: 4.147

Review 9.  Social relationships and mortality risk: a meta-analytic review.

Authors:  Julianne Holt-Lunstad; Timothy B Smith; J Bradley Layton
Journal:  PLoS Med       Date:  2010-07-27       Impact factor: 11.069

10.  Correlates of social and emotional loneliness in older people: evidence from an English community study.

Authors:  Lena Dahlberg; Kevin J McKee
Journal:  Aging Ment Health       Date:  2013-11-19       Impact factor: 3.658

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4.  A multi-cohort consortium for GEnder-Sensitive Analyses of mental health trajectories and implications for prevention (GESA) in the general population in Germany.

Authors:  Juliane Burghardt; Ana Nanette Tibubos; Danielle Otten; Elmar Brähler; Harald Binder; Hans Grabe; Johannes Kruse; Karl Heinz Ladwig; Georg Schomerus; Philipp S Wild; Manfred E Beutel
Journal:  BMJ Open       Date:  2020-02-25       Impact factor: 2.692

5.  Prevalence and new onset of depression and anxiety among participants with AMD in a European cohort.

Authors:  Jasmin Rezapour; Alexander K Schuster; Stefan Nickels; Christina A Korb; Hisham Elbaz; Tunde Peto; Matthias Michal; Thomas Münzel; Philipp S Wild; Jochem König; Karl Lackner; Andreas Schulz; Norbert Pfeiffer; Manfred E Beutel
Journal:  Sci Rep       Date:  2020-03-16       Impact factor: 4.379

6.  How is and how should healthcare for people with multiple sclerosis in Germany be designed?-The rationale and protocol for the mixed-methods study Multiple Sclerosis-Patient-Oriented Care in Lower Saxony (MS-PoV).

Authors:  Kathrin Krüger; Lara Marleen Fricke; Elise-Marie Dilger; Annett Thiele; Kristina Schaubert; Dyon Hoekstra; Fedor Heidenreich; Anna Levke Brütt; Jona T Stahmeyer; Alexander Stahmann; Anna-Lena Röper; Klaus-Peter Kubiak; Melissa Hemmerling; Anja Grau; Kerstin Eichstädt; Sabine Behrens; Christian Krauth
Journal:  PLoS One       Date:  2021-11-11       Impact factor: 3.240

7.  Mental health and loneliness in the German general population during the COVID-19 pandemic compared to a representative pre-pandemic assessment.

Authors:  Manfred E Beutel; Nora Hettich; Mareike Ernst; Gabriele Schmutzer; Ana N Tibubos; Elmar Braehler
Journal:  Sci Rep       Date:  2021-07-22       Impact factor: 4.379

8.  Course of depressive symptoms in men and women: differential effects of social, psychological, behavioral and somatic predictors.

Authors:  Ana N Tibubos; Elmar Brähler; Mareike Ernst; Carlotta Baumgarten; Joerg Wiltink; Juliane Burghardt; Matthias Michal; Jasmin Ghaemi Kerahrodi; Andreas Schulz; Philipp S Wild; Thomas Münzel; Irene Schmidtmann; Karl J Lackner; Norbert Pfeiffer; Andreas Borta; Manfred E Beutel
Journal:  Sci Rep       Date:  2019-12-12       Impact factor: 4.379

9.  People with multimorbidity in outpatient care: patient-focused and needs-oriented healthcare management (MamBo) - protocol for a multiperspective evaluation study.

Authors:  Simone Richter; Ibrahim Demirer; Kyung-Eun Choi; Johannes Hartrampf; Holger Pfaff; Ute Karbach
Journal:  BMC Health Serv Res       Date:  2020-04-13       Impact factor: 2.655

10.  The Bidirectional Relationship between Posttraumatic Stress Symptoms and Social Support in a 9/11-Exposed Cohort: A Longitudinal Cross-Lagged Analysis.

Authors:  Sze Yan Liu; Jiehui Li; Lydia F Leon; Ralf Schwarzer; James E Cone
Journal:  Int J Environ Res Public Health       Date:  2022-02-24       Impact factor: 3.390

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